Wednesday June 30 - Saturday July 3, 2021 - The Joint European Congress on Head and Neck Oncology (ECHNO) and the International Congress on ...
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The Joint European
Congress on Head and
Neck Oncology (ECHNO)
and the International
Congress on Innovative
Approaches in Head and
Neck Oncology (ICHNO)
www.echno-ichno2021.org
Wednesday June 30 -
Saturday July 3, 2021
• FINAL
PROGRAM
Introduction Committees
ORGANIZING COMMITTEE ECHNO
Dear Friends of the EHNS, Prof. W. Golusiñski EHNS President
Guy Andry Co-Chairman
Welcome to the online ECHNO/ICHNO 2021. Frederic Duprez Co-Chairman
Prof. Solange Peters ESMO President
For the first time in our history, the Presidents of the three societies: Prof. Ben Slotman ESTRO President
EHNS, ESTRO and ESMO decided to join forces to organize two major Joke De Ceulaer
scientific events together. The ECHNO/ICHNO 2021 online and ICHNO/
Paul Clement
ECHNO 2022 in traditional form in Brussels.
Jean-François Daisne
Marc Hamoir
I would like to thank our ESMO and ESTRO partners, as well as our
Colleagues from the Belgian Head and Neck Societies, for outstanding Olivier Lenssen
cooperation and preparation of a very compelling scientific Jean-Pascal Machiels
programme. I am certain that all of the hard work of everyone involved
in the organization of ECHNO/ICHNO 2021 will bear fruit in the form of
a fantastic congress which you are all attending. SCIENTIFIC COMMITTEE – ICNHO
Pierre Blanchard FR Representing ESTRO
Wojciech Golusiński C. René Leemans NL Representing EHNS
European Head and Neck Society President JP Machiels BE Representing ESMO
Mererid Evans UK Chair of the Advisory Committee for Radiation
Oncology
Sjoukje Oosting NL Chair of the Advisory Committee for Medical Oncology
Wojchiech Golusiński PL Chair of the Advisory Committee for Surgery
Ruud Brakenhoff NL Chair of the Advisory Committee for Head and Neck
Cancer Related Sciences
ADVISORY COMMITTEE FOR RADIATION ONCOLOGY
Mererid Evans UK Chair
Vincent Gregoire FR
Teresa Guerrero-Urbano UK
Florence Huguet FR
Hans Langendijk NL
Esat Mahmut Ozsahin CH
Claire Paterson UK
Silke Tribius DE
3
Committees Scientific Programme
WEDNESDAY 30 JUNE 2021
ADVISORY COMMITTEE FOR MEDICAL ONCOLOGY
Sjoukje Oosting NL Chair 14:40 Introduction to ECHNO-ICHNO 2021
Paolo Bossi IT Fréderic Duprez, Belgium and Guy Andry, Belgium
Irene Brana ES
ASHNO - EHNS Session: head and neck oncology practice: any difference between
Ana Castro PT Europe and Asia?
Robert Haddad US
Ulrich Keilholz DE Chairs: EUR: Jesper Eriksen, Denmark & ASIA: Mohd Razif Mohamad Yunus, Malaysia
Christophe Le Tourneau FR
14:45 Introduction by chair/moderator
Amanda Psyrri GR
EUR: Jesper Eriksen, Denmark & ASIA: Mohd Razif Mohamad Yunus, Malaysia
Anna Spreafico CA
15:00 Changing paradigms in head and neck surgery in Asia
Sheng-Po Hao, Taiwan
ADVISORY COMMITTEE FOR SURGERY
15:15 Update on nasopharyngeal cancer in Asia
Wojchiech Golusiński PL Chair
Marlinda Adham, Indonesia
Andreas Dietz DE
15:30 Epidemiology in head and neck cancer in Europe vs. Asia
Sefik Hosal TR
Sefik Hosal, Turkey
Antti Mäkitie FI
15:45 Make sense campaign in Europe
Haitham Mirghani FR
Ana Ferreira Castro, Portugal
Miguel Quer ES
16:00 Concluding remarks
Gregorio Sanchez Aniceto ES
Jean Bourhis, Switzerland
Christian Simon CH
Giovanni Succo IT Young Scientist’s Forum - Poster discussion from young scientists
Chairs: Pawel Golusinski, Poland & Amanda Psyrri, Greece & Piotr H. Skarzynski, Poland
ADVISORY COMMITTEE FOR HEAD AND NECK CANCER RELATED SCIENCES
Ruud Brakenhoff NL Chair 16:30 Introduction
Robert Ferris US Wojciech Golusinski, Poland
Jochen Hess DE
Keith Hunter UK 16:35 0.1 Association of anemia and hematological inflammatory biomarkers with
response to concurrent chemoradiotherapy on patients with squamous
Claus Andrup Kristensen DK
cell carcinoma of the head and neck
Max Robinson UK
Joana Correia Magalhães, Portugal
Susanne Singer DE
16:45 0.2 Prospective validation of an institutional treatment strategy for T1N0M0
Ingeborg Tinhofer-Keilholz DE glottic carcinoma
Rieneke van de Ven NL Simon Beyaert, Belgium
16:55 0.3 Complications in transoral laser microsurgery for carcinoma of the larynx
Laura Ruiz Sevilla, Spain
4 5
Scientific Programme Scientific Programme
17:05 0.4 An evaluation of the definition of close margin in squamous cell
THURSDAY 1 JULY 2021
carcinoma of the oral tongue and its possible prognostic significance
Zarah Abeln, The Netherlands
08:30 Opening - by Presidents of EHNS, ESMO and ESTRO
Wojciech Golusiński, EHNS & Solange Peters, ESMO & Ben Slotman, ESTRO
17:15 0.5 The unveiled reality of human papillomavirus as risk factor for oral
cavity squamous cell carcinoma
Irene Nauta, The Netherlands 08:40 Presidential Lecture
Chair: Wojciech Golusiński
“The European perspective” Surgical Innovation: Essential for Optimal Multidisciplinary Care
of Oropharyngeal Cancer
Chris Holsinger, USA
17:30 Implementing a European Network of Robotic Surgery: The EU-ROBOT.
Wojciech Golusiński, Poland
09:00 Best Presentation from Young Scientist’s Forum
17:45 EORTC present and future
Chairs: Pawel Golusinksi & Amanda Psyrri
Christian Simon, Switzerland
SESSION 1: FUTURE OF SURGICAL TREATMENTS.
AHNS-symposium: De-escalation of Therapy in the HPV Era
Chair: Jan Klozar, Czech Republic & Moderator: René Leemans, The Netherlands
Chair: René Leemans, The Netherlands & Moderator: Chris Holsinger, USA
09:15 I s there a role of TORS in management of p16+ unknown primary cancer
18:15 Introduction by chair/moderator
of the H&N?
18:30 Keynote lecture and surgical de-escalation strategies
Vinidh Paleri, United Kingdom
Cherie-Ann Nathan, USA
09:35 3D robotic like surgery
18:45 De-escalation strategies of systemic agents
Giovanni Succo, Italy
Jean-Pascal Machiels, Belgium
09:55 Novel techniques for endoscopic skull base surgery
19:00 De-escalation strategies in radiation oncology
Antoine Moya-Plana, France
Jimmy Caudell, USA
10:15 Image guided surgery
19:15 Closing the session
Max Witjes, The Netherlands
René Leemans, The Netherlands
10:35 Coffee Break
6 7
Scientific Programme Scientific Programme
SESSION 2: DEVELOPMENTS IN GENETICS AND DIAGNOSIS SESSION 3: RECURRENT HEAD AND NECK CANCER-Salvage treatments in recurrent
head and neck cancer
Chair: Ruud Brakenhoff, The Netherlands & Moderator: Pierre Saintigny, France
Chair: Vinidh Paleri, United Kingdom & Moderator: Jean-François Daisne, Belgium
11:05 Intratumor genetic heterogeneity: current status and clinical
relevance 14:00 Salvage surgery for locally recurrent head and neck cancer
Patrick Pauwels, Belgium Miguel Quer, Spain
11:25 Liquid biopsy analysis in H&N cancer 14:20 ocoregional reirradiation for recurrent head and neck cancer in the
L
Ingeborg Tinhofer-Keilholz, Germany IMRT and SBRT era
Vincent Gregoire, France
Proferred papers related to sessions 1-2 14:40 ystemic therapy as monotherapy and in combination in head and neck
S
cancer
Jan Vermorken, Belgium
Chair: Robert Takes, The Netherlands & Moderator: Ahmet O. IKIZ, Turkey
PANEL: Salvage treatments in recurrent head and neck cancer:
11:50 1.1 olecular patterns in salivary duct carcinoma identify prognostic
M
interactive case discussions
subgroups
Simon A Mueller, Switzerland
Moderators: Valentino Valentini, Italy & Antoine Digonnet, Belgium & Giovanni Succo, Italy
12:00 1.2 Ex vivo functional assay for predicting radiation treatment response in
squamous cell carcinoma of the head and neck
15:00 Panelists:
M.E. Capala, The Netherlands
Radiotherapy: Kenneth Jensen, Denmark & Oncology: Sjoukje Oosting,
12:10 1.3 Three-dimensional margin assessment in head and neck malignancies The Netherlands & Oncology: Amanda Psyrri, Greece, Surgery: Gilles Dolivet,
Jens Debacker, Belgium France; Surgery: Gregorio Sanchez Aniceto, Spain
12:20 1.4 GFR-targeted fluorescence guided surgery in head and neck
E
squamous cell carcinoma 15:40 Coffee Break
Jaron de Wit, The Netherlands
Proferred papers session 3
12:40 Lunch break & visit virtual sponsor booth
Chair: Antti Mäkitie, Finland & Moderator: Ben-Zion Joshua, Israel
12:45 Satellite symposium MSD
16:15 3.1 A circulating biomarker for the early detection of recurrent oral cancer.:
Visit page 17
Cathie Garnis, Canada
16:25 3.2 Salvage Treatment in Isolated Regional Recurrent Head and Neck
Squamous Cell Carcinoma
Roland Giger, Switserland
8 9Scientific Programme Scientific Programme
16:35 3.3 Nasopharyngeal brush Epstein barr viral DNA in the detection
of locally recurrent nasopharyngeal cancer
FRIDAY 2 JULY 2021
Jason Chan, Hong Kong
16:45 Concluding remarks
SESSION 5: HOW TO COMBINE IMMUNOTHERAPY WITH STANDARD OF CARE
New data from randomised trials
Chair: Andreas Dietz, Germany & Moderator Ana Ferreira Castro, Portugal
Chair: Ana Ferreira Castro, Portugal & Moderator: Andreas Dietz, Germany
08:30 Keynote lecture: Checkpoint inhibition in the radical setting for H&N SCC
Lisa Licitra, Italy
17:00 Introduction by the chair
09:00 Neo-adjuvant immunotherapy in HNSCC
Charlotte Zuur, The Netherlands
17:05 A DAHANCA-EORTC blind randomised multicentric study of
09:15 Radiation with immunotherapy
concomitant chemo-radiotherapy with or without the hypoxic cell
sensitiser Nimorazole for locally advanced p16-negative head and Kevin Harrington, United Kingdom
neck SCC. 09:30 Therapeutic vaccines in HPV+ disease
Vincent Grégoire, France Christophe Le Tourneau, France
17:20 Results of DARS: a randomised phase III trial of dysphagia-optimised
intensity modulated radiotherapy (DO-IMRT) versus standard IMRT Proferred papers related to session 5
(S-IMRT) in oropharyngeal (OPC) and hypopharyngeal (HPC) cancer.
Chris Nutting, United Kingdom
Chair: Drago Prgomet, Croatia & Moderator: Vincent Grégoire, France
17:35 Efficacy of Hyperbaric Oxygen in the Treatment of Osteoradionecrosis
of the Mandible. Results from the combined clinical trials
DAHANCA-21 and NWHHT2009-1. 09:45 5.1
Evaluation of pembrolizumab monotherapy in patients with salivary
François Dieleman, The Netherlands gland carcinoma in the phase 2 KEYNOTE-158 study
Caroline Evans, UK
SESSION 4: SALIVARY GLAND TUMORS 09:55 5.2 Immune Tumor Microenvironment and Response to Chemotherapy in
Laryngeal and Hypopharyngeal Squamous Cell Carcinomas
Luis Juesas Iglesias, Spain
Chair: Marc Hamoir, Belgium & Moderator: Gerhard Hüber, Switzerland
10:05 5.3 NBTXR3 activated by SBRT combined with nivolumab or pembrolizumab
in patients with advanced cancers: phase I trial
17:50 Keynote lecture: Histology-driven surgery in parotid carcinoma: Colette Shen, USA
fact or fiction?
Vincent Vanderpoorten, Belgium
10:15 Coffee Break
18:10 Panelists:
Surgery: Sefik Hosal, Turkey & Radiotherapy: Jean Bourhis, Switzerland &
Oncology: Laura Locati, Italy & Pathology: Andrzej Marszałek, Poland
18:50 End of congress day
10 11Scientific Programme Scientific Programme
SESSION 6: HOW WILL WE TREAT OUR PATIENTS NON-SURGICALLY IN 2030? SESSION 7: QUALITY OF CARE IN TREATMENT OF HEAD AND NECK CANCER AND
SURVIVORSHIP
Chair: Jesper Grau-Eriksen, Denmark & Jean-Pascal Machiels, Belgium
Chair: Andreas Dietz, Germany & Moderator: Giovanni Succo, Italy
10:45 Adaptive radiotherapy for dummies
Edmond Sterpin, Belgium 14:00 How to improve Quality of Care in Surgical Oncology.
11:05 Treatment adaptation for HPV positive disease. René Leemans, The Netherlands
Pernille Lassen, Denmark 14:20 What really matters is the radiation oncologist behind the machine
11:25 Systemic therapy: immune checkpoint inhibitors, still cisplatin, … Vincent Grégoire, France
Sylvie Rottey, Belgium 14:40 Optimizing the prescription doses and tolerability of systemic therapy
Thorsten Fureder, Austria
Proferred papers related to session 6 15:00 Health related quality of life from diagnosis up to 2 years after treatment:
evidence from NET-QUBIC
Irma Verdonck-de Leeuw, The Netherlands
Chair: Igor Reshetov, Russia & Moderator: Paul Clement, Belgium
15:20 Value based health care.
Yolande Lievens, Belgium
11:45 6.1 Radiation enhancing hafnium oxide nanoparticles (NBTXR3)
for the treatment of locally advanced HNSCC in elderly patients:
a phase I/II study Proferred papers related to session 7
Christophe Le Tourneau, France
11:55 6.2 Validation of USPIO-enhanced MRI for detection of lymph node Chair: Fréderic Duprez, Belgium & Moderator: Susanne Singer, Germany
metastases in head and neck carcinoma: a pilot study
Daphne Driessen, The Netherlands 15:40 7.1
The positive yield of multidisciplinary team decisions in a high volume
12:05 6.3 Can imaging alone replace panendscopy as a ‘gold standard’ head and neck center after those made in its preferred partner: An
investigation for patients with low risk features for oropharyngeal example of enhanced quality of care
cancer? J.J. Hendrickx, The Netherlands
Carolina Watters, United Kingdom 15:50 7.2 Do head and neck cancer patients in randomized trials represent the
12:15 6.4 The virtual MDT - the future or a fad? population in daily practice?
Hussein Mohamedbhai, UK Johannes Kaanders, The Netherlands
12:25 Concluding remarks
16:00 Coffee Break
12:30 Lunch / virtual booth visit
12:45 Satellite Symposium Merck
Visit page 18
12 13Scientific Programme Scientific Programme
SESSION 8: THYROID CANCER SATURDAY 3 JULY 2021
Chair: Dimitrios Moraitis, Greece & Moderator: Guy Andry, Belgium INVITED LECTURE
16:30 Surveillance vs. treatment of papillary thyroid cancer Chair: Evaldas Padervinskis, Greece & Moderator: José Luis Cebrián Carretero, Spain
Iain Nixon, United Kingdom
16:50 New treatment options in iodine-refractory thyroid cancer 08:30 Recommendations for treatment of head & neck cancer in 2021 - EHNS,
Laura Locati, Italy ESTRO and ESMO viewpoints
Amanda Psyrri, Greece
Proferred papers related to session 8
ebate: this house believes that transoral surgery is the standard of care in early stage
D
Chair: Ricard Simo, United Kingdom HPV+ oropharyngeal cancer
17:10 8.1 Further progress in the detection of thyroid carcinoma: Chair: Béatrix Barry, France & Moderator: Zhanna Kaliadzich, Belarus
the microRNAs supplant the gene mutations in fine-needle
aspiration biopsies. 09:00 For the motion
Marie Quiriny, France Chris Holsinger, USA
17:20 8.2 A Comparison of Differentiated Thyroid Cancer Presenting 09:15 Against the motion
in the UK Versus Internationally
Sandra Nuyts, Belgium
Rupali Sawant, UK
09:30 For the motion rebuttal
17:30 8.3 Ultrasound Scan Pre-Operative Localization of Recurrent Thyroid
Christian Simon, Switzerland
Cancer – Technique and Early Outcomes
09:45 Against the motion rebuttal
Chrysostomos Tornari, United Kingdom
Jean Bourhis, Switzerland
17:40 8.4 Correlation between thyroid fine needle aspiration cytology
and post-operative histology: A 10-year single-centre experience
High level proferred papers/clinical trials with results
Ahmad Abou-Foul, UK
17:50 Concluding remarks Chair: Patrick Sheahan, Ireland & Moderator: Pierre Blanchard, France
Ricard Simo, United Kingdom
10:00 9.1
Robotic lateral oropharyngectomy following diagnostic tonsillectomy
is oncologically safe in patients with human papillomavirus related
squamous cell cancer
Somiah Siddiq, UK
10:10 9.2 ransoral Laser Microsurgery for Oropharyngeal Squamous Cell
T
Carcinoma: Results in Equitable Survival and Enhanced Function
Compared with Contemporary Standards of Care
C. Lucy Dalton, UK
14 15Scientific Programme Satellite Symposium
10:20 9.3 Treatment outcomes and survival following definitive (chemo) Thursday 1 July - 12:45 - 14:00 hrs. Satellite symposium MDS
radiotherapy in HPV+ oropharynx cancer: Large scale comparison of
two population-based cohorts
Pernille Lassen, Denmark
EHNS, ESMO and ESTRO: future events, other important messages from the societies
10:30 EHNS
Wojciech Golusiński, Poland
EVOLVING TREATMENT ALGORITHMS FOR 1L R/M HNSCC
10:40 ESMO
Solange Peters, Switzerland
Faculty
10:50 ESTRO
Tanguy Seiwert, Johns Hopkins University Medical Center, Sidney Kimmel Comprehensive
Pierre Blanchard, France
Cancer Center Baltimore, Maryland, USA
11:00 ICHNO-ECHNO 2022 Brussels announcement
Jean-Pascal Machiels, Saint-Luc University Clinics, Department of Internal Medicine,
Pierre Blanchard, France Medical Oncology Service, Brussels, Belgium
11:05 ECHNO Lisbon Portugal 2023 announcement Denis Soulières, University of Montreal Health, Centre (CHUM) Integrated Cancer Center
Ana Castro, Portugal (CICC), Montreal, Quebec, Canada
11:10 Concluding remarks of the congress
Fréderic Duprez, Belgium & Guy Andry, Belgium Chair: Jean-Pascal Machiels (Belgium)
12:45 – 12:50 Welcome and introduction
Jean-Pascal Machiels
12:50 – 13:10 Advances in treatment of 1L R/M HNSCC
Denis Soulières
13:10 – 13:25 1L R/M HNSCC case studies with treatment algorithm discussions
Jean-Pascal Machiels
13:25 – 13:45 Future/ongoing development in HNSCC
Tanguy Seiwert
13:45 – 14:00 Q&A and closing remarks
All
16 17Satellite Symposium Sponsors & exhibitors
Friday 2 July - 12:45 - 14:00 hrs. Merck Medical Satellite Symposium Gold Sponsor
DOES ONE SIZE FIT ALL? – PERSONALIZING TREATMENT IN R/M SCCHN
Exhibitors
Faculty
Prof. Paolo Bossi (Italy), PD Philipp Ivanyi (Chairperson, Germany),
and Prof. Joël Guigay (France)
12:45 – 12:47 Introductory remarks
Philipp Ivanyi
12:47 – 12:59 Key factors in treatment decisions: The importance of patient needs
Paolo Bossi Organising societies
12:59 – 13:11 The evolving treatment landscape: Matching treatments to patients
Philipp Ivanyi
13:11 – 13:23 Treatment sequencing in R/M SCCHN: 1L and beyond
Joël Guigay
13:23 – 13:43 Putting the data into practice
All speakers
13:43 – 13:45 Closing remarks
Philipp Ivanyi
13:45 – 14:00 Live discussion
All speakers
18 19Notes Notes 20 21
VIRTUAL EVENT
Does one size fit all?
Personalizing treatment for R/M SCCHN
Join to hear expert insights at the
ECHNO-ICHNO Virtual Congress 2021
Date:
Friday 2nd July 2021
Time:
12:45–14:00 CEST
Philipp Ivanyi Paolo Bossi Joël Guigay
Introductory remarks Philipp Ivanyi, Germany
Key factors in treatment decisions:
Paolo Bossi, Italy
The importance of patient needs
The evolving treatment landscape:
Philipp Ivanyi, Germany
Matching treatments to patients
Treatment sequencing in R/M SCCHN:
Joël Guigay, France
1L and beyond
Putting the data into practice All
Closing remarks Philipp Ivanyi, Germany
Live discussion All
GL-ERBSCCHN-00166 | Date of preparation: June 2021
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UC 202200745EE ©2021 Medtronic. All rights reserved.
Medtronic and the Medtronic logo are trademarks of Medtronic.
All other brands are trademarks of a Medtronic company.ECHNO-ICHNO2021 Congress Secretariat
Congress Care
P.O. Box 440
5201 AK ’s-Hertogenbosch
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Tel: +31-73-690 1415
E: info@congresscare.com
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