Combined diet with - An integrated dietary protocol to obtain the best compliance of the overweight and obese patient - Dieta Combinata
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RESERVED FOR NUTRITIONISTS
Combined diet
®
with
An integrated dietary protocol
to obtain the best compliance
of the overweight and obese patient.
Dietosystem
Wellbeing as science
INTEGRATED DIETARY SCHEME
+ Personalised Diet
The Combined Diet® with PROTEONORM represents the the qualified answer to the need for a rapid weight loss, in
the event of overwight and obesity.
The Combined Diet® protocol with PROTEONORM is divided into 5 phases plus two additional: the preparation pha-
se (optional) lasting one week, pre-treatment diet and phase 0 or pre-bariatric, in which the feeding occurs exclusively
through an amino acidic mixture.
All the protocol phases involve the consumption of PROTEONORM, whose quantity is calculated based on the patient’s
weight as well as with a drastic reduction of carbohydrates. The optional introduction of high-protein hypoglucidic pro-
ducts of the new PROTEOFOOD line is permitted, right from the earliest and most restrictive stages.
WEIGHT LOSS TRANSITION MAINTENANCE
Preparation Phase 0 Phase 1 Phase 2 Phase 3 Phase 4 Phase 5
OPTIONAL PHASE – Preparation PHASE 2 – Transition diet 1 PHASE 5 – Maintenance diet
(7 days) (from 7 to 14 days) (from 7 to 14 days)
A slightly hypocaloric detoxifying menu. Low-calorie diet with a slight introduction Normocaloric diet on the model of the
Integration of 1 sachet/day of PROTEO- of carbohydrates and personalised nu- Mediterranean diet. Introduction of 1
NORM amino acidic mixture. trition with lean meats and vegetables sachet/day of PROTEONORM amino
Integration of 2 DRENORM stick-packs a with a low glycemic index. Integration of acidic mixture.
day to proote the body’s purification and 2 sachets/day of PROTEONORM amino Use of healthy and balanced foods in
water balance. acidic mixture. order to maintain a healthy weight.
Optional introduction of a single food
item of the PROTEOFOOD line, to be
PHASE 0 – Pre-bariatric diet chose from the products allowed in this
(10 days) phase.
Pre-bariatric surgery diet for patients with
a BMI ≥ 40 The diet requires the intake of at least
Feeding using only PROTEONORM ami- PHASE 3 – Transition diet 2 2 liters of mineal water per day.
no acidic mixture. About 10-15 sachets/ (from 7 to 14 days)
days. Low-calorie diet with a slight introduction
of carbohydrates and personalised nu- During the protocol we recommend
trition with lean meats and vegetables the following:
PHASE 1 – Attack diet with a low glycemic index. Integration of • 2 stick-packs of DRENORM per day
(from 14 to 21 days) 2 sachets/day of PROTEONORM amino to promote the purification and the
Diet consisting of a drastic reduction of acidic mixture. water balance of the body
carbohydrates and the introduction of Optional introduction of a single food • 1 sachet per day of PROTEOFOOD
lean meats and vegetables with a low item of the PROTEOFOOD line, to be to promote the basic/acid balance
glycemic index. Customised protein sup- chose from the products allowed in this of the organism.
plementation using the PROTEONORM phase.
amino acd mixture. Approximately 3-4
sachets/day. PROTEOFOOD foods allow the
Optional introduction of a single food PHASE 4 – Transition diet 3 reintroduction of “forbidden foods”
item of the PROTEOFOOD line, to be (from 7 to 14 days) guaranteeing the sustainability of the
chose from the products allowed in this Slightly low-calorie diet with increased ketogenic diet treatment with greater
phase. carbohydrates intake and personalised patient compliance, The progressive
nutrition with lean meats and low-glyce- reintroduction of carbohydrates, in
mic vegetables. Integration of 2 sachets/ the 3 transition phases, facilitates
day of PROTEONORM amino acidic the stabilisation of weight loss.
mixture. The maintenance phase is the final
Optional introduction of a single food step of the food protocol with a
item of the PROTEOFOOD line, to be Mediterranean style menu proposed.
chose from the products allowed in this
phase.
How to proceed
The Combined Diet® with PROTEONORM represents the answer to the need for rapid weight loss where the objective
conditions of the patient allow it.
It is recommended, when undertaking Combined Diet® with PROTEONORM, to monitor at least once a week
the serological parameters of the patient and periodically assess the changes in the FFM compartment and the level
of hydration of the patient with impedance analysis, in addition to verifying the patient’s ketosis.
FOR ALL NUTRITION EXPERTS (Doctors and Nutritional Biologists)
The Combined Diet® with PROTEONORM can be PROTEONORM is supplied:
processed directly online at www.combineddiet.it • To the nutritionist who prescribes it to his patient
after having registered (free of charge). Access to the or alternatively
site is exclusively reserved to Doctors and Nutritional • To the patient who will purchase the product directly
Biologists, who have been identified through the from Dietosystem, through the Contact Centre, Fax
WelfareLink protocol in order to safeguard the patient or Website by providing the purchase code*
and guarantee exclusive use to qualified health NOME
COGN
OME
professionals. After registration, the user accesses his
IG
BASSO
Premesse
alla
Dieta
Combinata
con
PROTEONORM
50
salute.
Il
menù
proposto,
unitamente
al
prodotto
Proteonorm,
Amararappresenta
una
Avena
nto
25
“soluzione
Pasta
integr
40
Bulgur
Quinoa
urgente”
al
suo
calo
ponderale.
Per
tale
ragione
le
consiglio
di
seguire
i
menù
per
la
sola
durata
Riso
selvatico
35
Kamut
ale
cotta
40
Biscotto
40
frolla
55
35
indicata
nello
schema
dietetico
senza
prolungarne
il
periodo
Farina e
attenersi
di
ceci
a
quanto
prescritto
Pasta
integr
ale
40
Riso
rosso
55
35
Pane
azzimo Tagliatelle
b
pesando
inizialmente
ogni
pietanza.
Solo
con
il
tempo
imparerà
Farina a
riconoscere
di
cocco
il
peso
35
delle
porzioni
Grano
s
40
Manioca
en
cotte
55
aracen 40
55
senza
bisogno
della
bilancia
e
scegliere
autonomamente
il
cibo
nella
quantità
35
e
qualità
Biscotto
più
o
Spaghetti
be
• patient data is entered
frolla
light
40
n
cotti
55
Pizza
corretta.
Se
non
potesse
seguire
tale
consiglio,
potrà
optare
per
le
seguenti
alternative:
Fiocchi
d’avena
40
55
Spaghetti
co Pane
al
latte
60
d
tti
40
Ravioli
tegrate
Farina
d 60
A. ridistribuire
gli
alimenti
a
suo
piacimento
nel
corso
della
giornata
Grano
i
quinoa
40
Semola
40
di
grano
d 60
B. scambiare
tra
loro
i
vari
giorni
di
dieta
evitando
di
ripeterli
Plan In
Farina
d Riso
lu uro
i
farro
45
ngo
60
Cous
cous
in Lasagne
C. sostituire
un
piatto
del
1°
giorno
con
quello
di
un
giorno
successivo
appartenente
alla
tegral 45
60
Dietary
Farina
d e
Orzo
perlato
• body composition obtained through the impedance
i
kamut
60
stessa
categoria
Pane
di
45
Farina
i
ntegra
60
kamut
45
Segale
Pane
integra le
45
le
60
Alcune
semplici
regole
comportamentali
l’aiuteranno
a
raggiungere
il
suo
obiettivo
cBulgur on
più
facilità:
Pane
nero
65
45
Mais
Riso
basmat 65
e
Farine
i
integra 45
Pane
di
-‐ masticare
lentamente
consente
di
digerire
e
assimilare
meglio
gli
alimenti,
raggiungendo
Riso
b asmati
li
45
segale
65
with
Muesli
Muesli
light
65
anticipatamente
la
sensazione
di
sazietà.
All
Bran
50
Brioches
method is entered
50
a l
cioccol 65
-‐ bere
2
litri
di
acqua
oligominerale
al
giorno
favorisce
l'eliminazione
Barret delle
tossine
ta
ai
cereali
50
Farro
ato
65
Riso
integral Farina
s
dall'organismo
e
50
emi-‐integral 65
Cereali
Pasta
integr Farina
d e
i
c 65
-‐ utilizzare
i
comuni
aromi
da
cucina
come
prezzemolo,
basilico,
rosmarino
Pane
de
salvia,
rende
i
quinoa
ale
le
50
Farina
di
g astagne
65
50
rano
duro
Riso
co
pietanze
più
appetibili
senza
ricorrere
al
sale
Biscotti
integra 50
mune
70
Cous
c li
Tacos
70
-‐ i
metodi
di
cottura
molto
semplici
come
bollitura,
bagnomaria,
al
forno
ous
e
alla
griglia
50
Gnocc
hi
70
• the food plan is developed
ted by:
50
consentono
di
preparare
le
pietanze
senza
l’aggiunta
di
olio
Tagliatelle
Elabora
70
Cereali
zuccherati
70
Name
Polenta
70
e Last LO
SCHEMA
DIETETICO
INTEGRATO
Fette
biscot
70
Dott. Nam Biologist
tate
Biscotti
comun 70
nal Corn
Flakes
i
Nutritio Il
menù
prevede
un’integrazione
proteica
personalizzata
tramite
il
prodotto
Proteonorm.
Pane
bianco
70
70
• the report with the header of your office is printed
sio, 100 Pane
di
Viale Ceni Integratore
alimentare
ad
alto
indice
proteico
contenente
magnesio,
potassio,
inositolo,
l-‐ riso
70
o Brioches
- Milan
20100
70
carnitina,
niacina
e
cistina
in
quantità
conforme
ai
fabbisogni
consigliati.
Miglio
70
Pane
azzimo
70
Il
prodotto
non
è
addizionato
da
aromi
al
fine
di
rendere
possibile
l’eventuale
assunzione
con
altre
Cialda
wafers
70
Crackers
bevande
tipo
caffè,
tea
e
cacao
amaro
se
graditi.
Riso
so
75
ffiato
80
• the prescription of PROTEONORM which includes
Gallette
85
Si
raccomanda
di
non
superare
la
dose
giornaliera
consigliata
e
non
utilizzare
il
prodotto
come
Pane
al
di
riso
latte
85
sostitutivo
di
una
dieta
equilibrata.
Pop
corn
85
Maizena
85
Farina
d
Come
utilizzare
Proteonorm:
Riso
a
c
i
grano
b
ianca
85
ottura
r 85
Tapioca
apida
85
Versare
il
contenuto
della
bustina
in
una
tazza
o
in
un
bicchiere
capiente
ed
aggiungere
acqua
o
the purchase code* is printed
Pane
bianca
no
glutine
85
altra
bevanda
non
zuccherata
(caffè,
orzo,
cacao
amaro,
tisane,
tea,
camomilla)
a
temperatura
Farina
d
i
riso
90
Fecola
ambiente
nof: elle
quantità
che
ne
permetta
la
completa
solubilizzazione.
95
ort
scientific supp 100
With the
FOR DIETOSYSTEM USERS
If you are already a user of the Dietosystem Nutritional Suite®, request the free Combined Diet® with PROTEONORM
module and receive an updated software that will allow you to manage the patient, prescribe the DIET and PROTEO-
NORM as well as manage and monitor the nutritional state, if equipped with impedanceometry and plicometry.
From the software module the prescription will be available for printing, including the purchase code*
PRESCRIZIONE INTEGRATORI
A SUPPORTO DELLA DIETA COMBINATA
ELABORATA DA PER
Dott. Nome Cognome Nome Cognome Paziente
Biologo Nutrizionista
Viale Cenisio, 100
20100 - Milano
Data visita 09/01/2017
Per il trattamento dietetico della durata di 21 giorni le ho prescritto
N. ___ confezioni di PROTENORM N. ___ confezioni di BISCOTTO MORBIDO AL CIOCCOLATO
N. ___ confezioni di PROTENORM MOUSSE N. ___ confezioni di BARRETTA AL CARAMELLO /LAMPONE
N. ___ confezioni di DRENORM N. ___ confezioni di BARRETTA AL CIOCCOLATO
N. ___ confezioni di DIETOLIP N. ___ confezioni di WAFER AL CIOCCOLATO
N. ___ confezioni di PROTEOBASIC N. ___ confezioni di PALLINE DI SOIA AL CIOCCOLATO
N. ___ confezioni di ELLEDIELLE N. ___ confezioni di CIOCCOLATO FONDENTE
N. ___ confezioni di GLYMELA N. ___ confezioni di CRACKER AI SEMI DI GIRASOLE
N. ___ confezioni di BISCOTTI ALLA VANIGLIA N. ___ confezioni di PATATINE AROMA BARBECUE
N. ___ confezioni di BISCOTTI ALL’ARANCIA N. ___ confezioni di PANE NERO CON SEMI VARI
N. ___ confezioni di PASTA
Per una scelta dell’azienda produttrice e per contenere il costo del trattamento potrà acquistare direttamente
il prodotto da DS Medica Srl, con una delle seguenti modalità:
ONLINE TELEFONO FAX
www.dietacombinata.it
selezionando sulla colonna Chiamando il Inviando il FORM sotto riportato
a sinistra il tasto Call Center consumatori debitamente compilato al numero
“ORDINA PROTEONORM” 02 2800 5725 02 8718 1182
Indirizzo fiscale Ragione sociale ____________________________________________
Cognome ______________________________________________________ Indirizzo di spedizione (se diverso)
Nome _________________________________________________________ Via ____________________________________________________________
Via ____________________________________________________________ CAP ___________________ Città __________________________________
CAP ___________________ Città __________________________________
Telefono ___________________ Cellulare ___________________________ Note: _______________________________________________________
eMail ___________________________ @_____________________________ _____________________________________________________________
C.F. |__|__|__|__|__|__|__|__|__|__|__|__|__|__|__|__|
Il costo del prodotto è fissato dall’azienda: Glymela € 22,00 a confezione Wafer al cioccolato € 24,00 a confezione
Proteonorm € 57,50 a confezione Biscotti alla vaniglia € 22,50 a confezione Palline soia cioccolato € 24,00 a confezione
Proteonorm Mousse € 27,50 a confezione Biscotti all’arancia € 15,00 a confezione Cioccolato fondente € 15,00 a confezione
Drenorm € 20,00 a confezione Biscotto morbido cioccolato € 16,00 a confez. Cracker semi girasole € 23,00 a confezione
Dietolip € 16,00 a confezione Barretta al caramello € 21,00 a confezione Patatine barbecue € 18,00 a confezione
Proteobasic € 22,00 a confezione Barretta al lampone € 21,00 a confezione Pane nero semi vari € 20,00 a confezione
Elledielle € 18,00 a confezione Barretta al cioccolato € 24,50 a confezione Pasta € 28,00 a confezione
Inviando il FAX si viene ricontattati dal Call Center per confermare l’acquisto e le modalità di spedizione.
In ogni contatto indichi il codice di prescrizione sotto riportato.
CONTRASSEGNO (costo aggiuntivo di € 5,00 IVA compresa)
BONIFICO BANCARIO
CONSENSO AL TRATTAMENTO DATI PERSONALI
CARTA DI CREDITO
Acconsento liberamente ai sensi dell’ART. 13 del D. Lgs 196/2003
Spese di spedizione € 7,00 IVA compresa. al trattamento e alla comunicazione e diffusione dei miei dati personali
nei limiti della stessa.
FIRMA
_______________________________________________________________
(*) Every single prescription generates a purchase code that guarantees that PROTEONORM is distributed exclusively on the basis
of a non-repeatable nutritionist’s prescription.
SCIENTIFIC RATIONALE
Combined diet
®
with
Traditional methods for weight reduction include low calorie diets (800 –
1500 kcal/day) balanced in nutrients and accompanied by regular physical
exercise. A “low carbohydrate diet” is a diet that includes less than 60 grams of
carbohydrates a day and is slightly high in protein, that foresees the intake of
protein based on the ratio of 1 to 1.5g per kilo of ideal body weight.
G.L. Blackburn (Harvard Medical School) coded the minimum amount of protein
needed to protect the organisms lean body mass in 1,2 – 1,5 grams per Kilo
of ideal weight1 and applied it in the low-calorie-protein-sparing diets (Protein
Sparing Modified Fast) identified by the acronym PSMF.
In 1993, the PSMF nutritional dietary protocol was validated by the FDA2, with
the coding of the minimum daily amount of protein needed to ensure the
equilibrium of the nitrogenous balance to avoid the mobilisation of protein
reserves and the consequent reduction of lean mass.
The application protocol was then further improved by the Swedish school3.
From 2003 to 2010 the Dutch Ministry of Health, as part of the obesity prevention
program, indicates the low-calorie, protein-saving diet treatment among the
first-level treatments for the treatment of obesity4.
Glucose
Reduction
Protein
Increase
Lipolysis
Decreases
insulin
Increases
glucagon
Triglyceride Lean body mass
Catabolism protection
Free Fatty
Acids Glycerol
40%
60%
beta
Gluconeogenesis
oxidation Lactates
Gluco-dependant
cells
INSULIN GLUCOSE
Corpi
chetonici
Krebs Cycle Energy
Oxidation
Acidosis
Combined Diet® with PROTEONORM is a high protein and low carbohydrate
content scheme. It generates two important processes, at metabolic level.
Carbohydrates
Proteins
Modest Ketosis
Thanks to this you obtain a reduction in the feeling of hunger, helping you
to avoid giving up the treatment and implement changes to your lifestyle,
in a healthy way5, 6.
Gluconeogenesis
With the reduction of carbohydrates, a rapid drop in insulin is obtained, which
prevents fat storage and stimulates lipolysis, especially in those areas where fat
deposits are located. The organism activates hepatic gluconeogenesis once the
energy reserves (glycogen) are used up – this usually occurs after 48 hours. This
process is critical in ensuring the amount of glucose for gluco-dependent cells,
such as red blood cells, the brain and the retina.
INDICATIONS AND CONTRAINDICATIONS
Like all medical treatments, even the low-calorie protein-saving diet has indications and contraindications that are
already defined in the protocol7-8.
Indicated in cases of: Contraindicated in cases of:
• Obesity: BMI > 30 • Type 1 (insulin dependent) diabetes mellitus
• Overweight: > 25 BMI < 29 • Renal impairments
• Overweight associated with risk factors: • Severe hepatic insufficiency
– Diabetes mellitus type 2 • Heart failure
(and insulin resistance) • Previous strokes
– Dyslipidaemia • Pregnancy and breastfeeding
– Metabolic Syndrome • Severe psychiatric disorders
– Asthma • Evolutionary neoplasms
– Sleep Apnoea • Boys/girls in developmental age
– Locomotor system Disorders • Senior citizens
• Aesthetic reasons • Psychogenic compulsive feeding disorders
– Localised Adiposity
• Pre-Surgery
• Intense Physical Activity
References 5. Asia Pac J Clin Nutr. 2006;15 Suppl:49-54. State of the science: VLED (Very
1. Diabetes. 1976 Jun;25(6):494-504. Low Energy Diet) for obesity. Delbridge E, Proietto J.
2. The National Task Force on the Prevention and Treatment of Obesity. Very 6. Finnish Diabetes Association. Development Programme for the Prevention
Low-Calorie Diets. JAMA 1993;270:967-74 and Care of Diabetes in Finland DEHKO 2000-2010.
3. Lancet 1997; 350: 423-6 7. Nutr Diabetes. 2014 Feb 10;4:e105.
4. DEHKO– Finnish Diabetes Association 2003 8. Int J Environ Res Public Health. Feb 2014; 11(2): 2092–2107.
For a constant updating of scientific works, refer to the news published on www.combineddiet.com21 sachets of 20 g
Food supplement made of soluble whey protein, enriched by Inositol, L-Carnitine,
L-Cistine, Niacin, Magnesium, Potassium.
PROTEONORM is a food supplement useful in case of increased need or decrea-
sed protein intake in the diet.
DOSAGE As recommended by the nutritionist.
DIRECTIONS Pour the contents of the sachet into a large cup or glass and add water or other
unsweetened beverages (coffee, barley, bitter cocoa, herbal tea, tea, chamomile)
at room temperature in quantities that allow complete solubilisation.
PROTEONORM Whey protein: micro and ultra-filtered with high solubility, is made up of oligo-
COMPONENTS peptides that is highly assimilable by the organism and passed directly through
the intestinal mucous membranes without undergoing digestive processes. Whey
protein does not contain traces of lactose or fat, so it does not favour intolerance
or allergic reactions. Whey protein has a very low glycemic index and contains all
the essential, non-essential and semi-essential amino acids with a significant con-
tent of branch chain amino acids.
Inositol: facilitates the detoxification processes of the organism, especially in the
liver. It also contributes to the metabolism of fats and helps reduce the concentra-
tion of cholesterol in the blood. Useful in case of constipation since it has a stimu-
lating effect on the muscular action of the alimentary canal.
L - Carnitine: amino acid that the body uses to convert fatty acids into energy. In
particular, it facilitates the entry of long chain fatty acids into the mitochondria.
Here, they undergo an oxidation process in order to produce energetic molecules
that can be used by the body.
L - Cystine: essential amino acid for the production of reduced glutathione, a mo-
lecule with an antioxidant detoxifying function for the body and in particular for
the liver. Its action promotes the proper functioning of the immune system.
Niacin: acts in its two forms, the NAD and the NADP. It becomes part, in coenzy-
matic form, as an electron acceptor in many reactions concerning the metabolism
of carbohydrates, fatty acids and amino acids. NAD intervenes in particular in the
reactions of glycolysis, lipolysis and in the Krebs cycle. NADH intervenes in the
metabolism of fats and steroids.
Magnesium: is involved in more than 300 enzymatic reactions in the body. It con-
trols the nervous and muscular activity and participates in the metabolic processes
of fats and protein synthesis.
Potassium: present in the form of an ion, mainly inside the cells but also in the
extracellular fluids, influences the activity of the skeletal muscles and the myocar-
dium. In particular, it regulates neuromuscular excitability, acid-base balance, wa-
ter retention and osmotic pressure.INGREDIENTS per 100g per 3 sachets
AND NUTRITIONAL Energy 257.60 Kcal 154.56 Kcal
VALUES (1078.31 KJoule) (646.98 KJoule)
Fats 0.21 g 0.12 g
— Saturated Fats 0.04 g 0.03 g
Carbohydrates 1.75 g 1.05 g
— Sugars 1.75 g 1.05 g
Whey Protein 75.10 g 45.06 g
Salt 0.14 g 0.09 g
Amino acidic Profile (in g)
L-Glutamic Acid 12.67 g 7.59 g
L-Leucine 8.10 g 4.86 g
L-Aspartic Acid 7.70 g 4.62 g
L-Lysine 6.90 g 4.14 g
L-Isoleucine 6.00 g 3.60 g
L-Valine 5.17 g 3.09 g
L-Phenylalanine 4.69 g 2.82 g
L-Threonine 4.69 g 2.82 g
L-Proline 3.85 g 2.31 g
L-Alanine 3.50 g 2.10 g
L-Serine 3.22 g 1.92 g
L-Histidine 3.00 g 1.80 g
L-Methionine 3.00 g 1.80 g
L-Tyrosine 1.82 g 1.08 g
L-Tryptophan 1.70 g 1.02 g
L-Cystine 1.54 g 0.93 g
L-Arginine 1.47 g 0.87 g
L-Glycine 0.98 g 0.60 g
with %NRV* (per 3 sachets)
Inositol 5.00 g 3.00 g
L-Citrulline 1.00 g 0.60 g
L-Ornithine 1.00 g 0.60 g
L-Carnitine 1.00 g 0.60 g
L-Cystine 0.50 g 0.30 g
Niacine 0.05 g 0.03 g 187.4 %
Potassium Citrate 7.35 g 4.41 g
— of which Potassium 2.50 g 1.50 g 75.0 %
Magnesium Citrate 2.67 g 1.59 g
— of which Magnesium 0.40 g 0.24 g 64.0 %
*NRV = nutritional reference values (in accordance with the regulation UE 1169/2011)
WARNINGS
• Do not exceed the daily dose recommended
by the nutritionist.
• Do not use during pregnancy and in children,
or for prolonged periods of time or if suffering from
any pathology, without consulting the doctor.
• Contains a source of phenylalanine.
• Keep out of reach of children below three years of age.
• The product must not be considered a substitute
of a balanced diet and a healthy lifestyle.
• Keep in a cool and dry place.
• Do not use the product after the expiry date shown
on the box and on each sachet.Rev. 02/2018
www.combineddiet.com
Contact center +39 02 2800 5700
Fax +39 02 2817 2299
nutrizione@dsmedica.info
www.dsmedica.info
Dietosystem
a DS MEDICA division
Office: Milan 20125, Viale Monza 133
Branches: Rome, Viale Regina Margherita 302
Naples, Via Jannelli 646
Certified UNI EN ISO 9001:2008 e UNI EN ISO 13485:2012
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