THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar

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THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
Noble

THE PHARMACEUTICAL
INDUSTRY’S ROLE IN THE
GLOBAL ENVIRONMENTAL
SUSTAINABILITY MOVEMENT
In this article, Alex Catino, Product Commercialisation Associate at Noble, discusses
current trends in the pharmaceutical industry in relation to environmental
sustainability in healthcare.

Environmental sustainability is a broad,        first Conference on the Human Environment,
expansive concept that can apply                which is widely considered one of the earliest
to everything from agriculture and              global meetings to discuss the environment,
manufacturing to building design. But how       conservation and sustainability.2 In
is it defined?                                  the early 1990s, “green brands” began
    The United States Environmental             to emerge, with companies using their
Protection      Agency      (EPA)     defines   environmental and sustainable business
sustainability based on an overarching          practices as selling points for consumers.
principle: “Everything that we need for         By 2012, sustainability had cemented itself
our survival and well-being depends,            in the collective conscience of consumers
either directly or indirectly, on our natural   and companies alike, with corporate social
environment. To pursue sustainability is to     responsibility (CSR) and triple bottom line
create and maintain the conditions under        reports that measure financial, social and
which humans and nature can exist in            environmental performance emerging as
productive harmony to support present and       standard responses to that consciousness.3
future generations.”1
    The creation of the EPA in 1970 is one      ENVIRONMENTAL SUSTAINABILITY
of many inflection points that sparked the      IN HEALTHCARE
modern global environmental movement.
In 1972, the United Nations (UN) held the       The WHO defines an environmentally
                                                sustainable health system as one that
                                                “improves, maintains or restores health,
                                                                                                          Alex Catino
                                                while minimising negative impacts on the                  Product Commercialisation Associate
      “Within the healthcare                    environment and leveraging opportunities                  T: +1 888 933 5646 ext 170
       sector, environmental                    to restore and improve it, to the benefit                 E: acatino@gonoble.com
                                                of the health and well-being of current
       sustainability involves
                                                and future generations.”4 Most importantly,               Noble
           using resources as                   human health is inextricably linked to the                121 South Orange Avenue
       efficiently as possible,                 health of the environment, according to the               Suite 1070
                                                Australian Medical Association.5                          Orlando
 without compromising the                                                                                 FL 32801
                                                   Within      the     healthcare     sector,
                                                                                                          United States
     quality of patient care.”                  environmental sustainability involves using
                                                resources as efficiently as possible, without             www.gonoble.com

44                                   www.ondrugdelivery.com                                      Copyright © 2020 Frederick Furness Publishing Ltd
THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
Noble

                                                                                                         A member company of the World Business
                                                                                                      Council for Sustainable Development,
“A major sustainability issue confronting the healthcare sector
                                                                                                      Aptar also recently joined the UN Global
    today is the number of hospitals that are ageing, meaning                                         Compact – the world’s largest citizenship
     their technologies and systems are becoming outdated.”                                           initiative, which focuses on universal
                                                                                                      principles in the areas of human rights,
                                                                                                      labour, the environment and anti-
compromising the quality of patient care.           and sustainability in mind. In a 2018             corruption. “We are extremely proud of
Strategies that can foster environmental            Pharma Manufacturing article on achieving         [our] commitment to reducing [Aptar’s]
sustainability within this sector are               sustainability in an evolving pharma              impact on the planet while creating quality
promoting efficient management of resources         sector, Tom Egan, Vice-President, Industry        products,” said Stephan Tanda, Aptar
and increasing sustainable procurement.             Services, PMMI, said: “Pharmaceutical             President and CEO.
   A major sustainability issue confronting         manufacturers must implement packaging               Aptar Pharma, part of AptarGroup,
the healthcare sector today is the number           solutions that minimise the environmental         is the company’s provider of innovative
of hospitals that are ageing, meaning their         impact of expanding product lines, build          drug delivery solutions to pharmaceutical,
technologies and systems are becoming               sustainability practices into the development     consumer healthcare and biotech customers
outdated. Managing the renovation or                of new delivery systems, seek utility savings     worldwide. Its patented Freepod multi-
replacement of these facilities in a sustainable    in new automation strategies and leverage         dose, preservative-free nasal spray device
way – using elements like green building            serialisation.” For example, the article          with GlaxoSmithKline’s Otrivin won
design and construction, and incorporation          says, when it comes to accurate dosing,           the World Packaging Organisation’s
of on-site renewable energy technology –            patients who achieve better results with oral,    prestigious WorldStar Award in 2019 for its
can have a direct impact on the environment         injectable or nasal sprays versus other formats   sustainability impact. The award annually
without impacting patient care.4                    provide a strong incentive for companies to       recognises advancement and excellence in
   The healthcare sector is seeing increased        offer those new delivery mechanisms.              packaging design and technology.
pressure to make commitments and tangible               These advancements in drug delivery
progress that positively impact both the            add to the growing variety of products on
environment and society. The global shift           the market. In addition, a shift towards
towards achieving a sustainable future              smaller batch runs allows for more
has made environmental stewardship an               product diversity. However, more frequent
expected norm.                                      changeovers on machinery are required to
                                                    deliver this diversity of products, which in
CURRENT TRENDS IN THE                               turn can have negative impacts on energy
PHARMACEUTICAL INDUSTRY                             consumption at the manufacturing level.

An ageing world population and improved             CSR FOR ENVIRONMENTALLY
access to healthcare in emerging markets            SUSTAINABLE DRUG DELIVERY
are driving increased demand within the
pharmaceutical industry. Manufacturers today        Today, socially and environmentally
are responding to the demand by producing           responsible pharmaceutical companies are
a wider variety of pharmaceutical products.         developing ways to produce their products
However, the resulting changes to production        more efficiently and sustainably. Companies
can conflict with sustainability objectives.        have created self-imposed targets and
   A key challenge for the pharmaceutical           initiatives to reduce the impact of their
industry is how to accommodate demanding            activities and products on the environment
production schedules and increased product          while keeping the patient and product
variety while also keeping the environment          efficacy top of mind (Figure 1).

                                                    APTAR IS A GLOBAL LEADER
                                                    IN SUSTAINABILITY
      A key challenge for the
     pharmaceutical industry                        One company making a difference in its
    is how to accommodate                           commitment to creating a more sustainable
                                                    future is AptarGroup, a global leader in
      demanding production
                                                    drug delivery, consumer product dispensing
    schedules and increased                         and active packaging solutions. Earlier this
   product variety while also                       year, Barron’s included Aptar on its list of        Figure 1: A reusable, resettable
                                                    the “100 Most Sustainable Companies in              Noble training autoinjector,
   keeping the environment                                                                              built to replicate the form and
                                                    America” for the second consecutive year,
                                                                                                        function of the true drug delivery
  and sustainability in mind.”                      and Newsweek named it one of “America’s             device upon which it is based.
                                                    Most Responsible Companies 2020”.

Copyright © 2020 Frederick Furness Publishing Ltd                                    www.ondrugdelivery.com                                   45
THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
Noble

                                                                                                                      Figure 2: Various Noble
                                                                                                                  patient training devices, all
                                                                                                                  of which are resettable for
                                                                                                                   ongoing use and practice.

NOBLE’S COMMITMENT                              them overcome their anxiety and fears –           shipping and more sharps waste. When a
TO ENVIRONMENTAL                                rather than using their single-use actual         patient uses a resettable training device,
SUSTAINABILITY INITIATIVES                      drug delivery devices filled with medication      they are more likely to receive a proper dose
                                                for practice, which requires disposal             when using the actual drug delivery device.
Noble, an Aptar Pharma company,                 after a single use. In addition, pharma           Simply put, when a patient gets it right the
promotes healthy patient outcomes for           companies often achieve cost reductions           first time, our footprint shrinks.
people who self-administer their drug           and support their own sustainability                  Noble is also an environmental
therapies through the development of            initiatives by using Noble’s resettable           steward when it comes to its packaging
robust training and onboarding solutions        training devices.                                 designs, balancing sustainability with
for the world’s top pharma brands and              There is an extraordinary, and often           an understanding that the patient and
biotech companies. The company shares           overlooked, downstream cost to the                product efficacy are key factors in the
Aptar’s commitment to creating a more           healthcare system when patients do not            design process (Figure 3). This commitment
sustainable future.                             comply with their self-administered drug          to sustainable packaging extends to Noble’s
    A prime example of how Noble                therapies – and noncompliance often               travel kits (Figure 4), which are designed to
contributes to a sustainable environment        begins because of a lack of upfront and           protect temperature-sensitive medications.
is through resettable training devices          ongoing training.                                     All materials used within Noble’s
(Figure 2). These reusable training devices        Not only does the patient suffer when          packaging are compliant with the
allow patients to repeatedly practise the       they do not receive the proper dose of their      Restriction of Hazardous Substances
use of autoinjectors, prefilled syringes and    medication, it also hurts the healthcare          (RoHS) directive that originated in
nasal delivery devices to educate themselves    system by creating the need for additional        the European Union to restrict the use
on proper usage technique and to help           goods and packaging, such as additional           of specific materials that are hazardous
                                                                                                  to the environment, including lead,
                                                                                                  mercury, cadmium, hexavalent chromium,
                                                                                                  polybrominated          biphenyls      (PBB),
                                                                                                  polybrominated diphenyl ethers (PBDE),
                                                                                                  and four different phthalates (DEHP, BBP,
                                                                                                  BBP, DIBP).6 Additionally, nearly all of
                                                                                                  the company’s packaging is also free of
                                                                                                  harmful chemicals such as paint and
                                                                                                  electroplated plastic components.

                                                                                                  CONCLUSION

                                                                                                  Due to pressing environmental needs, a
  Figure 3: A Noble patient
                                                                                                  focus on preserving the environment for
  training kit made with
  recyclable materials.                                                                           future generations and a shift to more
                                                                                                  responsible consumption and production,

46                                   www.ondrugdelivery.com                                    Copyright © 2020 Frederick Furness Publishing Ltd
THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
Noble

                                                     companies have embraced more sustainable             order to increase patient adherence and
                                                     strategies. The link between sustainability,         confidence and decrease usage errors.
                                                     both environmental and social, has clear ties        Noble is an Aptar Pharma company.
                                                     to human health, making advancement of
                                                     these strategies a priority for healthcare and       REFERENCES
                                                     pharmaceutical industries alike (Figure 4).
                                                                                                          1.	“Learn About Sustainability”. Web
                                                     ABOUT THE COMPANY                                        Page, US Environmental Protection
                                                                                                              Agency, Accessed August 2020.
                                                     Noble is focused on fostering healthy                2.	“Report of the United Nations
                                                     patient outcomes for those who self-                     Conference on the Human
                                                     administer drug therapies through the                    Environment, Stockholm, 5-16 June
                                                     development of robust training devices and               1972”. UN Digital Library, 1973.
                                                     onboarding solutions for the world’s top             3.	Silvis J, “Connecting Sustainability to
                                                     pharma brands and biotech companies.                     the Healthcare Mission”, Healthcare
                                                     Noble manufactures and commercialises                    Design Magazine, May 29, 2012.
                                                     training devices that mimic the exact feel,          4.	“Environmentally Sustainable Health
Figure 4: A reusable Noble travel kit
that is temperature controlled to                    force and function of drug delivery devices              Systems: A strategic document”.
keep medications at their optimal                    such as autoinjectors, prefilled syringes and            WHO, February 7, 2017.
temperature while away from home.                    on-body, nasal and pulmonary devices in              5.	“Environmental Sustainability
                                                                                                              in Health Care – 2019”.
                                                                                                              Position Statement, Australian
  ABOUT THE AUTHOR                                                                                            Medical Association Web Page,
  Alex Catino, Product Commercialisation Associate at Noble, an Aptar Pharma company,                         March 20, 2019.
  is responsible for supporting development, launch and commercialisation of Noble’s                      6.	“RoHS Compliance FAQ”.
  platform products. Alex holds BSc degrees in business administration and psychology.                        RoHS Guide Web Page, Accessed
                                                                                                              August 2020.

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Copyright © 2020 Frederick Furness Publishing Ltd                                     www.ondrugdelivery.com                                             47
THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
Working
towards a more
sustainable
future.
At Noble, we feel it's our responsibility to help
ensure a more sustainable future for our patients
and customers, which is why we're proud to offer
reusable training devices and recyclable packaging.

                   © 2020 Noble International, LLC. All rights reserved.   Noble Speaks Patient ™
THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
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