UANDES Technology Portfolio - DECEMBER 2020

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UANDES Technology Portfolio - DECEMBER 2020
DECEMBER 2020
     UANDES Technology Portfolio

01
UANDES Technology Portfolio - DECEMBER 2020
In this document we present the portfolio of UANDES
     technologies developed by our researchers and spin-offs.

     Technologies were classified by product type considering
     regulations and definitions from the FDA and US and UK
     universities.

     Technological transfer success stories are shown (green - exit).

02                                                   UANDES Technology Portfolio | DECEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
JOURNEY CHART OF OUR TECHNOLOGIES
        11/20/2020                                                                                                                                                                                                                                   Page 1
         Clinica                        F.EDU                             F.ING                               F.MED                                       F.ODO
                                                                                                                                       Page 1
F.ING         F.MED                               F.ODO                                                                                                                                                            Scheme of
                                                                                                                                                                                                                                UA-M0016
                                                                                                                                                                                                                                 the University’s
                                                                                                                                                                                                    UA-M0033                  UA-M0039
                                                                                                                                                                                              UA-M0012
                                                                                                                                                                                           UA-M0038
                                                                                                                                                                                        UA-M0028
                                                                                                                                                                                                                    portfolio classifiedUA-M0027
                                                                                                                                                                                                                                                 inside
                                                                                                                   UA-M0016
                                                                                                                                                                                                                     out by: Faculty, Industry,    UA-M0021
                                                                                          UA-M0033                                     UA-M0039
                                                                                    UA-M0012
                                                                                 UA-M0038                                                                                                                        4
                                                                                                                                                                                                                     5
                                                                                                                                                                                                                       Product
                                                                                                                                                                                                                           3
                                                                                                                                                                                                                                   Type, TRL and
                                                                                                                                                    UA-H0002                                                                                               UA-M0010
                                                                              UA-M0028                                                                   UA-M0027
                                                                                                                                                                                                                             Technology
                                                                                                                                                                                                                                      5
                                                                                                                                                                                                                                               5
                                                                                                                                                                                                                                                 Code.         UA-M0
                                                                                                                                           UA-H0001                              UA-M0021
                                                                                                              5                   3                                                                                                                                                                      UA-
                                                                                                                                      UA-N0001                                                                           Food                 Veterinary
                                                                                                       4                                                                                                                                                                                 4
                                                                                                                                                                        4                     UA-M0010
                                             UA-H0002                                                                                                 5                                                                                                        Industrial process            3             U
                                                                                                                                                                  2                                    UA-M0036
                                     UA-H0001                                                                                                                           5                                                                                                  COA
                                                                                                                                                                                                           UA-M0035                                                                            5
                                   UA-N0001                                                                 Food             Veterinary                                                                                                      Agriculture                            Medical device
                                                                 4                                                                                             Medical device 4
                                                                                                                                                    Industrial process                  3                    UA-M0011                                      Earth exploitation
                                                            2
                                                                                                                                                                  COA                                                                                                Health
                                                                                                                                                                                        5
                                                                                                                           UA-I0034
                                                                                                                         Agriculture                                                  Health
                                                                                                                                                                             Medical device
                                                        Medical device
                                                                                                                                               Earth exploitation
                                                                                                                                                          4
                                                                                                                                                         Health                                                                                   F.MED

                             UA-I0034                                         Health
                                                                                                                  UA-I0038
                                                                                                                                                          Industrial p&p                                   Clinica

                                                    4                                                                                          4
                                                                                                                                      F.MED
                                                                                                            UA-I0040                                       SaaS              Agriculture
                UA-I0038                                                                                                                                                                                                                      Portafolio 2020
                                                  Industrial p&p                                  Clinica                                  3
                                                                                                            UA-I0042                                Software
                                         4                                                                                                               Telecomunication
                                                                                                                                                       H&S                                         F.ING                                         UA-O0012
             UA-I0040                              SaaS              Agriculture                                                      4
                                                                                                            UA-I0009                                                                                                                                                      F.ODO
                                    3                                                                                        Portafolio 2020                                                                                                           UA-O0020
            UA-I0042                         Software                                                                                                             Industry tech
                                                  Telecomunication                                                                                                                                                                                          UA-O0006
                                                                                                                                                                                                                                 7
                                                                                                                                                Industrial p&p                    Energy
                                                H&S                                       F.ING
                                     4                                                                                                                                           Environment Social                                      5                     UA-O0022                              Health
                                                                                                                                                3            H& S                                                                            F.EDU
             UA-I0009                                                                                                                                         F.ODO
                                                                                                                                                                                                                                              4
                                                            Industry tech                                         UA-I0043                                                                                                                                      UA-O0048
                                                                                                                                                                      H&S                                                 Medical device
                                         Industrial p&p                                                                                             10                                                                                3                         UA-O0046
                                                                          Energy
                                                                         Environment Social                                                                                 Equipment                  Health                                                  UA-O0038                                    V
                                         3           H&S                                                                 F.EDU
                                                                                                                                                                                            Software
                                                                                                                       UA-I0021
                UA-I0043                                                                                                                                      4                                                           Dental device
                                                                H&S                                                                                                                                                                   4
                                             10
                                                                                                                                                                                                                                                               UA-O0030
                                                                 Equipment                                                                                                   6                                                           3
                                                                                                                                                                                                             Vaccines & bio                   F.EDUcation                                            5     6
                                                                                   Software                                            UA-I0037                                                3
                        UA-I0021                                                                                                                                                                                                     5                       UA-O0036
                                                        4
                                                                                                                                                                                                                                                           UA-O0013
                                                                                                                                                          UA-I0010                                                        4
                                                                     6                                                                                                                                               3                               UA-O0004
                                   UA-I0037                                                                                  F.EDUcation                                                               5     6                                                                                           UA-
                                                                                      3                                                                                       UA-I0041                                                       Platform
                                                                                                                                                                                                                                             UA-O0029
                                                  UA-I0010                                                                                                                                                                UA-O0021
                                                                                                                                                                                                                       UA-C0013
                                                                      UA-I0041                                                                                                                                   UA-O0008
                                                                                                                                                                                                           UA-O0005 10             5
                                                                                                                          Platform                                                                                              1

                                                                                                                                                                                                                                     2

                                                                                                                                                                                                     UA-E0004                                             UA-E0003
                                                                                                             10                        5                                                                UA-E0002                                      UA-E0008
                                                                                                                              1                                                                                                                 UA-E0010
                                                                                                                     2                                                                                                          UA-E0009
                                                                                            UA-E0004                                        UA-E0003
                                                                                               UA-E0002                                 UA-E0008
                                                                                                                                  UA-E0010

                                                                                                                    UA-E0009

   03                                                                                                                                                                                                   UANDES Technology Portfolio | DECEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
DEVELOPMENT STAGE
                                                                                         1· Preliminary results and proof of concept
DECEMBER 2020                                                                                                           2· Prototype
OUR TECHNOLOGY PORTFOLIO                                                                                   3· Exit / Market adoption

 VACCINES, BLOOD & BIOLOGICS
                                                                                    LEAD                          IP
     CODE    TECHNOLOGY          DESCRIPTION                                                              DL
                                                                                    RESEARCHER                    PROTECTION

                                 Biomaterial formulation for the encapsulation
  UA-                            and release of allogeneic MSC and growth
             Cellistem ER                                                           Claudia Brizuela
 O0008                           factors in the regeneration of vascularized
                                 dental pulp tissues.

                                 New periodontal bone defects regeneration
  UA-        GelX: Bone Tissue
                                 method using allogeneic MSC and GelX               Alejandra Chaparro
 O0021       Engineering
                                 scaffold.

                                 Formulation and validation of copper-
  UA-        nanoCu
                                 based nano-formulations for biomedical and         Ziyad Haidar
 O0029
                                 regenerative medicine applications.

                                 Directly injectable nanocapsules for the
  UA-                            bi-phasic release of growth factors in the
             SG radioProtect                                                        Ziyad Haidar
 O0005                           radioprotection of salivary glands of head and
                                 neck cancer patients.
             Menistem’s          Menistem’s exosomes: antitumor effect
  UA-        Exosomes:           Evaluation of anticancer effect of menstrual
                                                                                    Francisca Alcayaga
 C0004       Antitumor Effect    stem cells (Men-SC) exosomes and its
                                 derivatives in different cancers.

  UA-        Menistem: SDRA      Men-SC/secretome use for the treatment of
                                                                                    Jimena Cuenca
 C0005                           SDRA.

                                 A method for producing a multilayered
      UA-                        composite of fibers and biopolymer layers,         Juan Pablo
             STEN Tech
     C0012                       capable of encapsulate cells and factors for the   Acevedo
                                 replacement or patching of different tissues.

  UA-        Cellistem™: Gum     Gum regeneration method using allogeneic
                                                                                    Alejandra Chaparro
 C00013      Regeneration        stem cells.

                                 A therapy based on a especific UC-MSC
             Lupus
  UA-                            subgroup for the treatment of lupus
             Erythematosus                                                          Fernando Figueroa
 R00001                          erythematosus.

                                 A technology that comprises Men-SC in a
  UA-        Wound Healing       scaffold for improving the regeneration of skin
                                                                                    Jimena Cuenca
 R0004                           ulcers.

04                                                                                         UANDES Technology Portfolio | DICEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
DEVELOPMENT STAGE
                                                                                         1· Preliminary results and proof of concept
                                                                                                                        2· Prototype
                                                                                                           3· Exit / Market adoption

 MEDICAL DEVICE

     CODE                                                                           LEAD                          IP
             TECHNOLOGY          DESCRIPTION                                                              DL
                                                                                    RESEARCHER                    PROTECTION

  UA-        Bipolar disorder    Protein biomarkers in peripheral blood
                                                                                    Úrsula Wyneken          1
 M0035       biomarkers          for the diagnosis of bipolar disorder.

             Neuro
             developmental
  UA-                            Biomarkers for early detection of prenatal
             changes                                                                Federico Batiz          1
 M0036                           stress-induced neurodevelopmental changes.
             prenatal
             biomarkers

  UA-                            A biomaterial with unique properties for 3D        Juan Pablo
             GelX: Life-Ink                                                                                 2
 M0010                           tissue printig.                                    Acevedo

      UA-    GelX:               Use of GelX matrix to improve the regeneration
                                                                                    Javier Enrione          2
     M0011   Biocomposite        of skin ulcers.

  UA-        PregnosticA:        Use of oral fluids to predict the development of
                                                                                    Alejandra Chaparro      2
 O0006       Preeclampsia        preeclampsia in early pregnancy.

             PregnosticA:
  UA-                            Use of oral fluids to predict the development of
             Gestational                                                            Alejandra Chaparro      2
 O0020                           gestational diabetes in early pregnancy.
             Diabetes Mellitus

  UA-        PregnosticA:        Use of oral fluids to predict the a premature
                                                                                    Alejandra Chaparro      1
 O0046       Premature Birth     birth in early pregnancy.

             Oral fluids
  UA-        biomarkers          Use of oral fluids microvesicles as biomarkers
                                                                                    Alejandra Chaparro      1
 O0038       for Chronic         of chronic periodontitis progression.
             Periodontitis

      UA-                        New method of forensic dentistry for obtaining
     O0012   DFK                 genetic profiles, estimating data and cause of     Patricio Carrasco       3
                                 death without damaging the tooth.

  UA-
                                 A bio-adhesive multi-compartmental thin-film
 O0022       Oro-Aid3                                                               Ziyad Haidar            2
                                 membrane (Oroaid).

05                                                                                        UANDES Technology Portfolio | DECEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
DEVELOPMENT STAGE
                                                                                       1· Preliminary results and proof of concept
                                                                                                                      2· Prototype
                                                                                                         3· Exit / Market adoption

 MEDICAL DEVICE
                                                                                                               IP
     CODE   TECHNOLOGY         DESCRIPTION                                       LEAD RESEARCHER       DL      PROTECTION

  UA-                          Electrostimulation for the regeneration of
            VitalOss                                                             Ziyad Haidar             1
 O0048                         tissue.

                               Design and implementation of a safety
                               device for adult hospitalized patients who
  UA-
            Safe toilet        require assistance during their stay in the WC,   Pilar Martinez           1
 N0001
                               safeguarding their security and privacy.

                               Establishment of optimal load range alignment
                               in computed tomography
  UA-
            Foot align         Under load, and design of the optimal load        Aarón Cortés             1
 H0001
                               range alignment module for the foot during a
                               loaded radiograph.

  UA-       Anti-COVID19       EPP mask for protection against COVID-19 with
            mask with copper                                                     Aarón Cortés             2
 H0002                         copper nanoparticles.
            nanoparticles

                               A migration device that allows to evaluate stem
  UA-                                                                            Juan Pablo
            Stellium           cells potency by the quantification of uniaxial                           3
 C0011                                                                           Acevedo
                               cell migration response.

 DENTAL DEVICE
                               A combinatorial device for the safe and sound
  UA-       X’PLANT 3Ss        retrieval of osseointegrated dental implants
                                                                                 Ziyad Haidar             2
 O0004      Dental             from the jawbone (Combi-Head, Combi-Tip and
                               Combi-Adapt).

                               A natural polymer-based, stimuli-responsive
  UA-
            SockGEL            and injectable hydrogel formulation for use in    Ziyad Haidar             1
 O0013
                               dental extraction socket preservation.

  UA-
            BioFLOSS           A novel nano-enforced bioactive dental floss.     Ziyad Haidar             2
 O0030

                               Determination of non-invasive molecular
  UA-       Pulp pathology
                               biomarker for the early diagnosis of pulp         Claudia Brizuela         1
 O0036      diagnosis
                               pathology.

06                                                                                      UANDES Technology Portfolio | DECEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
DEVELOPMENT STAGE
                                                                                       1· Preliminary results and proof of concept
                                                                                                                      2· Prototype
                                                                                                         3· Exit / Market adoption

 COA (CLINICAL OUTCOME ASSESMENT)
                                                                                                                IP
     CODE    TECHNOLOGY         DESCRIPTION                                      LEAD RESEARCHER        DL      PROTECTION

      UA-                       Implementation of a network for the care and     Francisco
             R.A.D.A.R                                                                                    2
     M0021                      detection of adolescents at risk of suicide.     Bustamante

 FOOD
             Bioactive
      UA-                       Obtaining functional activity peptides from
             Peptides from                                                       Javier Enrione           2
     M0012                      quinoa proteins.
             Quinoa

      UA-                       Development of edible coating for salmon
             GelX: Gel-Coat                                                      Javier Enrione           2
     M0016                      fillets.

  UA-                           New starch-cellulose biocomposite with low
             Starch-cellulose
 M0028                          digestibility level and post-consumption         Paulo Díaz               2
             composites
                                glycemic index.

  UA-
             Quinoa Flour       Process for obtaining quinoa functional flour.   Javier Enrione           2
 M0033

  UA-                           Bioactive peptides from fishing industry waste
             GelX: hydrolyzed
 M0038                          (salmo salar skin).                              Javier Enrione           2

 ANIMAL & VETERINARY
  UA-                           Device for the diagnosis of pregnancy or
             Sheep Chip                                                          Sebastián Illanes        1
 M0039                          multiple pregnancy in sheep cattle.

07                                                                                      UANDES Technology Portfolio | DECEMBER 2020
UANDES Technology Portfolio - DECEMBER 2020
DEVELOPMENT STAGE
                                                                                     1· Preliminary results and proof of concept
                                                                                                                    2· Prototype
                                                                                                       3· Exit / Market adoption

 PLATFORM
                                                                                LEAD                          IP
     CODE    TECHNOLOGY         DESCRIPTION                                                           DL
                                                                                RESEARCHER                    PROTECTION

             Dia+: Diamat for
                                Technology platform for evaluation and
  UA-        children from
                                assessment of math skills in children.          Kattia Muñoz            3
 E0002       kinder to 4th
             grade
             Dia+: Diamat for
                                Technology platform for evaluation and
  UA-        children from
                                assessment of math skills in children.          Kattia Muñoz            1
 E0009       kinder to 5th to
             8th grade
                                Platform to exercise reading skills based
  UA-
                                on reading lexiles: increases reading
 E0003       Dia+: Leer+                                                        Pelusa Orellana         2
                                comprehension and vocabulary.

  UA-                           Technology platform for the diagnosis and
 E0004       Dia+: Dialect      assessment of reading skills in students from   Pelusa Orellana         3
   /8                           kindergarten to 12th grade.

                                Technology platform for the diagnosis and
      UA-    Dia+: Dialect
                                assessment of reading skills in children from   Pelusa Orellana         1
     E0010   home
                                kindergarten to 4th grade, for use at home.

08                                                                                    UANDES Technology Portfolio | DECEMBER 2020
DEVELOPMENT STAGE
                                                                                         1· Preliminary results and proof of concept
                                                                                                                        2· Prototype
                                                                                                           3· Exit / Market adoption

 SOFTWARE
                                                                                   LEAD                           IP
     CODE    TECHNOLOGY          DESCRIPTION                                                              DL
                                                                                   RESEARCHER                     PROTECTION

                                 Preliminary conceptual development of an
      UA-    Mapuche
                                 ABM model for modernization of the Mapuche        Juan Pérez               1
     I0040   Cooperative
                                 agricultural cooperative.

             Transparency
      UA-                        Web platform for transparency in public
             in public                                                             Carla Vairetti           1
     I0042                       electronic procedures.
             proceadures

                                 Computational tool that allows microscopic
      UA-
             Public Transport    modeling of a sequence of bus stops on a          Rodrigo Fernández        1
     I0041
                                 highway.

 SaaS
      UA-                        Subway passengers density detection system
             Detpax                                                                Sebastián Seriani        2
     I0038                       through image analysis.

 HARDWARE & SOFTWARE
      UA-    Laser               Using laser technology as a secure
                                                                                   Jaime Anguita            2
     I0009   communications      communications system.

      UA-    Predictive system   Monitoring system for diagnosis and prognosis
                                                                                   Rodrigo Astroza          2
     I0037   for wind tower      of structural damage in wind turbines.

                                 Classifies almonds according to size, shape and
UA-I0021     Almond classifier                                                     Pablo Zegers             3
                                 damage.

09                                                                                        UANDES Technology Portfolio | DECEMBER 2020
DEVELOPMENT STAGE
                                                                                     1· Preliminary results and proof of concept
                                                                                                                    2· Prototype
                                                                                                       3· Exit / Market adoption

 INDUSTRIAL PROCESS & PRODUCT

      CODE                                                                      LEAD                          IP
             TECHNOLOGY        DESCRIPTION                                                            DL
                                                                                RESEARCHER                    PROTECTION

             Enzymes for
   UA-                         Characterization of psychophile enzymatic
             Biofuel and/or                                                     Felipe Scott            2
  I0034                        activity for industrial uses.
             Food Industries

   UA-       Self Curing       Development of an additive for the auto-curing
                                                                                Álvaro Paul             1
  I0043      Concrete          of concrete.

 INDUSTRIAL PROCESS
   UA-                         Biomaterial obtained from waste from the
             GelX                                                               Javier Enrione          2
  M0027                        aquaculture industry.

 INDUSTRIAL EQUIPMENT & HOME
   UA-
             Bio indoor air    Biological technology for removing indoor air
  I0010                                                                         Alberto Vergara         2
             purifier          pollutants.

010                                                                                   UANDES Technology Portfolio | DECEMBER 2020
SUCCESS STORIES

011                     UANDES Technology Portfolio | DECEMBER 2020
DEVELOPMENT STAGE
                                                     1· Preliminary results and proof of concept
                                                                                    2· Prototype
                                                                       3· Exit / Market adoption

                                                                           TTO CONTACT

                                                                      Silvana Becerra
      Deputy director of development and marketing • sbecerra@uandes.cl • +56 2 2618 1209

                                                                    Camila Baerwald
                                 Project Manager • cbaerwald@uandes.cl • +56 2 2618 2191

                                                    More info: innovacion.uandes.cl

012                                                   UANDES Technology Portfolio | DECEMBER 2020
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