Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma

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Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
Artificial Intelligence in Pharma:
What it Means for Patient Trust
 The unexpected ways that AI can increase
         patient trust in pharma
Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
AI-driven transformation has come at the right time
for the pharmaceutical industry.

Historically, public opinion toward the pharmaceutical                Human outcomes and accuracy
industry has tended to be dominated by controversy. From
the hiking of drug prices to pharma’s role in the current             Ultimately, the pharmaceutical industry is publicly tasked
North American opioid crisis, a 2017 survey by Ipsos/MORI             with saving and improving patient lives. This means the
shows that only 48% of more than 18,000 people across                 single most effective way to earn patient trust is to drive
23 countries believe pharmaceutical companies will treat              and demonstrate better health outcomes. As Thom et. al.
them fairly [1]. Within healthcare, pharmaceuticals is the            state, trust can be defined as "the acceptance of a vulnerable
only sector without an upward trajectory for public trust [2].        situation in which the truster believes that the trustee will act
In light of this, pharmaceutical executives are now forced to         in the truster’s best interests", and AI highlights the connection
actively manage publicly broken trust.                                between pharma and patient interests [4]. AI-powered data
                                                                      analytics uses real world evidence to reveal patterns in
Meanwhile, pharmaceutical executives are under intense                data which cannot be discovered by the human eye. This
pressure to compete with innovative new technologies in a             data-driven pattern recognition is used to form evidence-
rapidly shifting market, driving greater efficiency and returns       based predictions, and enables a move from aggregated to
on investment. Artificial Intelligence (AI), with its potential for   personalised analysis, which can deliver effectively tailored
big data and predictive analytics, has become a central focus         treatments and drastically improve patient outcomes. AI
in this move towards efficiency in pharma. According to a             moves us from asking “how are patients responding to
recent report, the combined applications of AI can create             treatment X?” to “how will patient X respond to treatment Y in
$150 billion in annual savings for the US healthcare economy          the future?” or “which treatment will be best for this patient,
by 2026 [3]. However, recent high-profile data breaches               and why? ”. And this technology is no longer in the future - it’s
have made it painfully clear that successful adoption of AI-          here. Already in 2012, OKRA Technologies’ CEO Dr Loubna
powered analytics must take customer trust into careful               Bouarfa was predicting surgeons’ movement to improve
consideration. In 2019, AI and trust management are fully             surgical workflows in the operating room. Her subsequent
able to positively reinforce each other, in unexpected ways.          OKRA analytics engine has already produced more than a
                                                                      million predictions for global top 10 pharma companies, to
So, how can pharma adopt AI whilst maintaining - and even             improve efficiency and accuracy.
improving - patient trust?
                                                                      In this sense, the basic promise of pharma and the
                                                                      basic promise of AI are highly compatible.

    In 2019, AI and
trust management
are fully able to
positively
reinforce each
other, in
unexpected                                                                                                              The OKRA platform,

ways.
                                                                                                                       answering real world
                                                                                                                      and market questions
                                                                                                                               in real time.
Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
Explainability, transparency and provability                     and there is some room to question the level of transparency
                                                                 that consumers wish for. A recent study in the Harvard
The pharmaceutical industry, and healthcare in general,          Business Review demonstrated that transparency exists
is firmly grounded in evidence based reasoning. This             on a scale, and while users will not trust “black box” models,
means that consumer trust is usually grounded in reliability     they also do not want full levels of transparency. Consumers
and explainability - of being able to explain, motivate          do not require deep mathematical insight into an algorithm
and reproduce results. At first sight, AI technology might       - merely basic insights on the factors driving algorithmic
counteract evidence-based trust; it is often described as        decisions [5]. This can easily be demonstrated through
a “black box”, where users are kept from knowing why an          reason codes, as mentioned above, which is also in line with
algorithm proposes a particular decision. To ensure that         EU GDPR stipulations on the “right to explanation of decisions
AI-supported decision-making is trusted, it must clearly         made by automated systems”. By finding the best level of
demonstrate what its recommendations are based on, and           transparency, AI adopters can demonstrate an evidence-
at what level of certainty.                                      based approach, whilst avoiding unnecessary technical and
                                                                 communicative difficulty.
Firstly, the ability to “explain” AI recommendations is here -
OKRA provides so called reason codes, a set of short natural     Data access and security
English sentences that explain why a given recommendation
is made. We include what data sources the model has used,        A central component to an AI workflow is access to data.
and the level of accuracy attached to a specific prediction or   Artificial intelligence uses mathematical models to recognise
analysis. Furthermore, AI-powered analytics engines such         patterns in data, beyond what humans can perceive. These
as OKRA have vast processing power that allows for more          patterns are then used to make relevant evidence-based
evidence to be processed. In combination with human              analyses and predictions of the future. AI needs data to
interpretation of outputs, AI supports pharmaceutical            function, which means AI adopters must consider data-
employees to process more data points in shorter amounts         related concerns.
of time, with replicable and more precise results.
                                                                 To gain the trust of consumers, there are a number of ways
Secondly, explainability and transparency are not absolutes,     to improving the security of patient data, and further ways

                                                                      By finding the best
                                                                 level of transparency,
                                                                 AI adopters can
                                                                 demonstrate an evidence-
                                                                 based approach, whilst
                                                                 avoiding unnecessary
                                                                 technical and
                                                                 communicative difficulty.
Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
of ensuring public perception of that security. Firstly, public         Furthermore, from a technical viewpoint, AI models can
 attitudes towards data sharing within the healthcare industry           be optimised for privacy, for example by using “privacy-
 are more optimistic that we might expect. A recent report               preserving machine learning” models that reduce the risk of
 suggests that as long as safety and security are perceived to           re-identifying patients within aggregated data.
 be safeguarded, consumers are likely to consent to sharing
 their data. Secondly, we can assume that this confidence                Conclusion
 grows with a sense of control of one’s data [6]. The EU’s GDPR
 is a significant step in this direction, building trust not by direct   First movers on AI in pharma have the opportunity to
 insight, but by a sense of regulatory control. As the European          communicate these measures clearly, and not only win
 Union is set to deliver its first-ever comprehensive framework          trust but also significant savings through low-cost proofs of
 on AI in Europe - to be launched in Q2 2019 - pharma                    concept. Pearson and Raeke conclude that patient trust is
 companies have a unique opportunity to communicate                      supported by 5 key factors that mirror a successful patient-
 compliance with upcoming EU legal frameworks, relying on                physician relationship: competence, compassion, reliability,
 established institutions to build trust with consumers. OKRA’s          integrity, and open communication [7]. As AI vendors
 CEO, Loubna Bouarfa, is a member of the European High-                  are establishing strong case studies for reliability and
 Level Expert Group on Artificial Intelligence and represents            competence, pharmaceutical adopters should communicate
 the interests of both industry and patients. In a recent                their commitment to human outcomes (compassion), data
 multi-stakeholder workshop on AI in European healthcare,                security strategies (integrity), with open communication at a
 hosted by OKRA’s CEO and other EU High-Level Experts, a                 level of desired rather than complete transparency - for the
 top concern was patient control over data. This area is set             benefit of both patients and company bottom lines.
 to figure prominently in the European Commission’s policy
 recommendations, which pharma should choose to align                    Risking customer trust can be a key barrier to adopting
 with.                                                                   transformative AI technology in the pharmaceutical industry.
                                                                         However, by taking the evidence-based approach that
 Loubna Bouarfa working as part
 of the European High-Level
                                                                         pharma does so well in other areas, executives and marketers
 Expert Group on                                                         can highlight AI’s role in driving precise, improved patient
 Artificial intelligence
                                                                         outcomes. Evidence suggests that AI can deliver $150 billion
                                                                         in annual savings to serious adopters, and the healthcare
                                                                         industry cannot delay their digital journeys. With the use of AI,
                                                                         and in partnership with trusted vendors, patient and market
                                                                         objectives converge.

                                                                                               Pharma
                                                                                         companies have a
                                                                                         unique opportunity
                                                                                         to communicate
                                                                                         compliance with
                                                                                         upcoming EU legal
                                                                                         frameworks, relying
                                                                                         on established
                                                                                         institutions to
      Follow
OKRA Technologies                                 Contact us
                                                                                         build trust with
on LinkedIn to read
   our upcoming
                                            to explore how AI can
                                             drive results in 2019.
                                                                                         consumers.
 2019 report series.                         okra.ai/contact-us
Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
First movers on AI in pharma have the opportunity
to communicate these measures clearly, and not only
win trust but also significant savings through low-cost
proofs of concept.

Authors

                                                                               Rasim Shah
                                                                         OKRA Chief Revenue Officer

                        Ida Svenonius                                                                                          Toby Hackett
         OKRA Marketing and Communications Manager                                                                       OKRA UK Account Manager

About OKRA Technologies
At OKRA Technologies, we work with global pharmaceutical companies to drive competitive insight with validated gold
standard accuracy. We provide an artificial intelligence analytics tool, designed to learn what truly drives health and
market outcomes, and trigger instant action. OKRA combines all your data sources in one place and gives you one
evidence-based view of the truth, accessible across teams, time and space. With artificial intelligence, we answer not only
what happened before, but what will happen in future and why - all in real time.

References
[1] ‘A Crisis of Trust’ Ben Page (2017), Chief Executive Ipsos/MORI. https://www.ipsos.com/sites/default/files/ct/news/documents/2017-09/a-crisis-of-trust-ben-page_0.pdf
[2] ‘2018 Edelman Trust Barometer - Healthcare: Global’ Edelman (2018). https://www.edelman.com/sites/g/files/aatuss191/files/2018-10/Edelman_Trust_Barometer_Global_Healthcare_2018.pdf
[3] ‘Artificial Intelligence : Healthcare’s New Nervous System’ Accenture (2017). https://www.accenture.com/t20171215T032059Z__w__/us-en/_acnmedia/PDF-49/Accenture-Health-Artificial-
Intelligence.pdf#zoom=50
[4] Thom, David H. et.al. (2004). 'Measuring Patients’ Trust In Physicians When Assessing Quality Of Care', Health Affairs, 23 (4).
[5] ‘We Need Transparency in Algorithms, But Too Much Can Backfire’ Harvard Business Review (2018) https://hbr.org/2018/07/we-need-transparency-in-algorithms-but-too-much-can-backfire
[6] ‘Through the looking glass - A practical path to improving healthcare through transparency’ KPMG (2017) https://assets.kpmg.com/content/dam/kpmg/xx/pdf/2016/08/through-the-looking-glass.
pdf
[7] Pearson, D. Steven & Lisa H. Raeke (2001). 'Patients' Trust in Physicians: Many Theories, Few Measures, and Little Data', Journal of General Internal Medicine, 15 (7).
Artificial Intelligence in Pharma: What it Means for Patient Trust - The unexpected ways that AI can increase patient trust in pharma
Contact us today
to explore how AI can
 drive results in 2019.

 okra.ai/contact-us

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