Neuroscience Antibodies & Protocols - (U.S.A. & European edition) 2006 - www.abcam.com
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Neuroscience Antibodies & Protocols (U.S.A. & European edition) 2006 www.abcam.com
Contents
Welcome to Abcam
Catalogue contents
About Abcam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 The team . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Neuroscience at Abcam . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2 Benefits of an Abcam account . . . . . . . . . . . . . . . . . . . . . . . .3
Neuroscience Abwire . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2 AbreviewsSM and Abcam AbpointsSM . . . . . . . . . . . . . . . . . . . .3
Abbreviations
Species key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 Applications key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Neuroscience antibody categories
Cell adhesion proteins Oxytocin & Vasopressin . . . . . . . . . . . . . . . . . . . . . . . . . .30
Cytoskeletal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 Thyroid Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30
ECM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 Neuronal markers
Membrane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10 Glia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31
Nuclear . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10 Neural Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33
Growth & development Neuron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35
Axonal Guidance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11 Neurotransmission
Neurogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11 Calcium Signaling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
Neurotrophins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12 Intracellular Signaling . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
Notch Pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13 Neurotransmitters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .47
Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14 Neuropeptides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .50
Neurodegeneration Nitric Oxide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52
Alzheimer’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18 Pharmacological Tools . . . . . . . . . . . . . . . . . . . . . . . . . . .53
Huntington’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22 Receptors & Channels . . . . . . . . . . . . . . . . . . . . . . . . . . .53
Parkinson’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22 Secretory Vesicles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .59
Prions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24 Transporters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .61
Related Targets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25 Sensory pathways
Neuroendocrinology Hearing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
GH Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26 Nociception . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
Gonadotrophic Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26 Olfaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
HPA Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27 Touch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
Obesity & Metabolism . . . . . . . . . . . . . . . . . . . . . . . . . . .28 Vision . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
Technical help
Neuroscience resources at Abcam . . . . . . . . . . . . . . . . .64 Neuroscience protocols and tips . . . . . . . . . . . . . . . . . . .66
Product datasheet guide . . . . . . . . . . . . . . . . . . . . . . . . .65 Neuroscience signaling pathway diagrams . . . . . . . . . . .85
Ordering and contact details
Contact details . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89 Required Information for ordering . . . . . . . . . . . . . . . . . . . .89
Ways to order . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89 Abcam’s terms and conditions . . . . . . . . . . . . . . . . . . . . . . .90
Coming soon
New Neuroscience antibodies . . . . . . . . . . . . . . . . . . . . . . .91
Target index
Target index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
Neuroscience resources: www.abcam.com/neuroscience
Welcome to Abcam
About Abcam
Abcam, located in Cambridge, U.K. and Cambridge, MA, U.S.A., was founded in 1998 by Dr. Jonathan
Milner, then a researcher at Cambridge University, U.K.:
“Like many life science researchers, I was frustrated by the time it took to locate and select
antibodies essential for my research. This was largely due to poor information and out-of-date
catalogs from the vast range of suppliers who were spread across many countries. In some cases, I
also experienced difficulties with companies whose products were unreliable and whose customer
service was slow and unhelpful. My vision was to build a company that offered reliable cutting-edge
Welcome to Abcam
products and great customer service.”
It was a tough vision - Abcam was created to sell the best antibodies in the world with the most comprehensive, honest and
up-to-date datasheets, fast delivery, helpful customer service and comprehensive technical support.
Seven years on and with thousands of products across our range, Abcam ships to
scientists in over 55 countries around the world. Abcam is committed to the
following fundamental principles that have seen us become the first choice
for thousands of life-scientists throughout industry and academia:
• Quality of products and datasheets
• Helpful technical support and online technical resources
• Friendly customer service
• Fast delivery
Comprehensive
We have a policy of honesty - our customers know everything that we know about
our products, as soon as we know it. Everything we know about each product is
posted on the datasheet. To achieve exceptional levels of quality for our customers
we provide:
• Comprehensive datasheets.
• Customers’ AbreviewsSM of our products .
• Product-specific protocols used by our customers.
• Customers’ technical questions and our answers for each product.
• Product information and new products updated daily. ...all at www.abcam.com!
Helpful
Our Technical Support and Customer Service departments are full of scientists that have many years of experience working
with the types of products that we supply to our customers.
We provide continuous order progress updates, so that you always know what is happening with your order and when you
should expect to receive it.
The Queen's Award for Enterprise
The Queen's Award for Enterprise has been running since 1966 and is widely recognised as the premier
award for business performance in the UK; granted annually for outstanding business achievement.
Abcam demonstrated excellent year-on-year growth in overseas sales between 2002 and 2004 with 84%
of sales during these three years coming from overseas customers. The award is positive proof of the
company's outstanding success as a customer-focused international business.
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 1
Free services
The World’s Antibody Gateway search engine
If we do not have the product that you are looking for use this service to search all online catalogs of other antibody suppliers.
Find the “WAG” at:
www.abcam.com/antibodygateway
The Abcam Toolbar
Directly search your choice of Abcam, GenBank, Google, LocusLink, OMIM, PubMed, SWISSProt. The toolbar sits within your
Welcome to Abcam
internet browser, so that you can use it from wherever you are on the internet. Get this useful facility at:
www.abcam.com/toolbar
Fast
We have developed web-based systems that enable us to quickly identify cutting-edge products, make them rapidly available
to our customers and then deliver them by Express Delivery.
We are pleased to be able to offer next-day delivery to all major cities as well as same day delivery to customers in Cambridge
U.K. and Cambridge MA, U.S.A.
Neuroscience at Abcam
Our range of over 2,000 Neuroscience primary antibodies has a breadth and depth that is hard to beat. Further more, we
collaborate with leading academics to make the Abcam range one of the best in the world!
The Neuroscience Abwire
Our Neuroscience Abwire web page is full of exclusive articles, product browsing tools, conference and publication information
and specialist protocols. Visit today for cup-to-date information in this rapidly progressing field.
Look out for new Neuronal Marker IHC Galleries, Neurodegeneration and Neurotransmission signaling pathway diagrams and
Neuroscience Product Locator tools (to name but a few).
Visit: www.abcam.com/neuroscience for more.
The Neuroscience team
Abcam has a specialized team working on sourcing and testing the best Neuroscience antibodies available. Our background in
the neurosciences is very strong to better serve our customers. Members include:
Technical Support Sarah and Bill help customers
Sarah Mardle (PhD King’s College, University of London, U.K.) who have enquiries about, or
Technical Support Manager (U.K.) problems with, Abcam
antibodies using their extensive
PhD and postdoctoral laboratory
experience.They also:
• Attend conferences to keep
up-to-date with antibody
Bill Campbell (PhD Brown University, U.S.A.) techniques and research
Technical Support Manager (U.S.A.)
• Source new protein targets
• Source novel techniques
using antibodies
• Build collaborations with
academics.
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
2 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience at Abcam
The Neuroscience team
Business Development
Sabrina Edmonds (PhD University of Cambridge, U.K.)
Business Development Manager for Neuroscience
Sabrina is responsible for sourcing new and exciting protein targets to generate antibodies against by
attending conferences, forging collaborations with academics and by reading current literature. She is
Welcome to Abcam
the main contact for academics who are interested in licensing their neuroscience antibodies for sale
through Abcam.
Marketing
Rhian Hayward (PhD University of Oxford, U.K.)
Neuroscience Marketing Manager
Rhian is responsible for marketing Abcam’s Neuroscience range to our customers worldwide. She
ensures that Abcam supports many Neuroscience community activities through conference
sponsorships, informative marketing materials e.g. signalling pathways (see page 83), the
Neuroscience Abwire and more.
Suggestions or comments: Email the team at neuroscience@abcam.com
Benefits of an Abcam Account
Take full advantage of all our online Neuroscience resources by opening an account.
• Earn Abcam AbpointsSM
• Buy quickly and efficiently online.
• Customise your antibody updates. We can notify you by email of new and updated antibodies related directly to the
protein families which interest you.
AbreviewsSM
Our unique system for enabling our customers to feedback to you and us about the performance of our primary antibodies. It is
important to know how our antibodies perform under different conditions and that they are working as expected. We encourage
this feedback (positive and negative) by awarding AbpointsSM for each Abreview:
AbreviewTM Action Points Description
Submit an Abreview 50 Each unique combination of antibody, application and sample species that you
review, earns you Abcam AbpointsSM, e.g. if you use one of our antibodies in
WB on Human and Mouse samples and submit an Abreview for both these
combinations, then you will receive 50 Points for each one.
Submit an Abreview 200 As for “Submit an Abreview” but for an antibody that has not yet been tested in
(untested application / that particular species or application.
species)
Submit an image with your 100 If you submit an image to accompany any of your Abreviews, then you will
Abreview receive extra Points when it is published with your Abreview. For Abreview and
image publication criteria, please see the Abreviews section of our website.
Fast Track Abreviews 950 Be the 1st researcher to submit conclusive positive or negative data (through
bonus Abreviews see below) about one of our Fast Track antibodies and earn this bonus
(in addition to the Abcam Points that you will earn for submitting your Abreview).
Customers’ Abreviews are posted on the product datasheets for others to browse. You can contact the reviewer to ask further
questions too!
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 3Abcam AbpointsSM
In addition to AbreviewsSM, you can also earn AbpointsSM by buying your antibodies online at www.abcam.com or by registering
your interests there.
AbpointsSM rewards
• Vouchers for leading retailers:
Welcome to Abcam
• Useful gifts:
• Discounts on Abcam products:
• Money to go to conferences / for journal subscriptions:
• Donate money to charities: ...You can even suggest new rewards.
Collecting and spending
Read about collecting and spending AbpointsSM and get the complete list of rewards for your country at: www.abcam.com/abpoints.
Check out the
latest at
www.abcam.com
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
4 Neuroscience resources: www.abcam.com/neuroscienceAbbreviations
Species key
Key Species Key Species Key Species
Many wide range of species Fe Ferret Pi Pig
Fi Fish P Plants
At Arabidopsis thaliana Gt Goat Q Quail
Am Amphibian G Goose Rb Rabbit
Av Avian Gp Guinea pig Rt Rat
Ba Baboon Ha Hamster Re Reptiles
Bu Burkholderia spp. H Horse Ro Rodents
Ca Cat Hu Human Sc Sacchromyces cerevisiae
Ce Caenorhabditis elegans In Insect S Salamander
Ch Chicken K Kangaroo Sha Shark
C Cow Li Lizard Sh Sheep
De Deer Mm Mouse Sn Snake
D Dog Ma Mammals X Xenopus laevis
Dm Drosophila melanogaster Mi Mink Y all Yeast
Abbreviations
El Elk Mk Monkey
Ec Escherichia coli Op Opossum
Applications key
Key Applications Key Applications
AF Acetone fixed IHC-P Immunohistochemistry (Formalin-fixed
Agg Agglutination paraffin-embedded sections)
AI Adhesion inhibition IM Immunomicroscopy
AP Affinity purification Inhib Inhibition assay
BL Blocking IP Immunoprecipitation
CCIe Counter current IRMA Immunoradiometric assay
immunoelectrophoresis ISH In situ hybridization
ChIP Chromatin immunoprecipitation Mct Microcytotoxicity testing
Conjugation Conjugation Neut Neutralizing
DID Double immunodiffusion P Purification
Dot Dot blot PA Prothrombin assay
EC Experimental control PCC Primary cell culture
EIA Enzyme immunoassay PCR Polymerase chain reaction
ELISA ELISA RIA Radioimmunoassay
EM Electron microscopy RID Radial immunodiffusion
EMSA Electrophoretic mobility shift assay RIe Rocket immunoelectrophoresis
FACS Fluorescence activated cell sorting RImm Radial immunodiffusion
FC Flow cytometry RipA Radioimmunoprecipitation assay
FuncS Functional studies SB Southern blot
GSA Gel supershift assays TCC Transfected cell culture
H Histology TLC Thin layer chromatography
I-ELISA Indirect ELISA WB Western blotting
IA Immunoassay
IB Immunoblotting Other
ICC Immunocytochemistry Fast Track Application and species data pending
ID Immunodiffusion Pep. avail. Peptide available
Ie Immunoelectrophoresis
IF Immunofluorescence
IHC Immunohistochemistry
IHC-F Immunohistochemistry (Formalin fixed sections)
IHC-Fr Immunohistochemistry (Frozen sections)
Many of the images in this catalog have been supplied by Abcam’s collaborators in the Neuroscience field. We wish to thank all
these contributors and we look forward to working with you in the future!
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 5Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
GARP (truncated) P WB Rb Rt, B ab15094
GFAP P IF, IHC-Fr Ch Hu, Mm, Rt, F, C ab4674
GFAP P IF, IHC-F, IHC-P, IP, PCC, WB Rb F, B, Hu, Mm, Pi, Rt ab7260
GFAP P IF, IHC-F, IHC-Fr, IHC-P Rb Hu, Rt, B ab7779
GFAP [2A5] M IF, IHC-F, IHC-P, PCC, WB Mm Ma ab8136
GFAP [6F2] M IHC-Fr, IHC-P, IM,
TEM immunogold labeling, WB Mm Hu ab8975
GFAP [GF-01] M ICC, IHC-Fr, IHC-P, IP, WB Mm Hu, F, Pi
Does not react with Mm or Rt ab7806
GFAP (phospho T7) [YC10] M ICC, WB Mm Hu, C, Pi
Does not react with Mm or Rt ab12340
Internexin alpha P ICC, IHC-Fr, WB Rb Hu, Mm, Rt, C, F ab22038
Internexin alpha [1D2] M ICC, IHC-P, WB Mm Hu, Rt ab22039
Internexin alpha [2E4] M ICC, IHC-Fr, IHC-P, WB Mm Hu, Rt ab22040
Laminin P ELISA, IF, IHC-P, RIA Rb Hu ab23753
Laminin P ELISA, WB Ch Hu, Mm, Rt ab14055
Laminin P Dot, IF, IHC-F, IHC-P Rb Ma, Am, Av, Re ab11575
Laminin [A5] M ICC, IHC-Fr, WB Rt Hu, Mm, Ba ab2500
Laminin [LAM-89] M IF, IHC-P Mm Hu, F, Rb.
Does not react with Mm, Rt, Ch, D,
Gp, Li, Pi, Sh or Sn ab11574
Cell adhesion proteins
Laminin [MEC5] M IHC-Fr Rt Hu, Mm, Rt ab2466
Laminin 2 alpha [4H8-2] M ELISA, ICC, IF, IP, WB Rt Hu, Mm ab11576
Laminin 5 P IHC-Fr, WB Rb Hu ab14509
Laminin B2 gamma 1 [SPM277] M IF, IHC-P, IP, WB Rt Hu, Mm ab17792
Laminin S [C4] M IP, WB Mm Hu, Rt, B, Pi, Gp, Ch ab3289
67kDa Laminin Receptor P ICC, IF, IHC-P, IP, WB Rb Hu, Mm ab711
67kDa Laminin Receptor [MLuC5] M FACS, ICC, IF, IHC-P Mm Hu, Rt ab3099
Nestin P ICC, IF Rb Hu, Ha, Mk
Does not react with Mm ab5968
Nestin [10C2] M IF, IHC-Fr, IHC-P, WB Mm Hu.
Does not react with rodent nestin ab22035
Nestin [2C13A11] M FACS, ICC, IP, WB Mm Hu.
Does not react with Rt ab18102
Nestin [2Q178] M EM, ICC, IHC-Fr, IHC-P, WB Mm Mm, Rt
Does not react with Hu, F, Mk or Sh ab6142
Nestin [3k1] M ELISA, FACS, ICC,
IHC (aldehyde-based fixation), IP, WB Mm Hu ab6320
68kDa Neurofilament [1D2] M ICC, IF, IHC-Fr, IHC-P, WB Mm Hu, Rt ab4571
68kDa Neurofilament [NR4] M IF Mm Hu, Rt, Ch, Pi ab11219
68kDa Neurofilament [SPM204] M IHC-P, WB Mm Hu ab17832
70 kDa Neurofilament Light P IHC-F, IHC-Fr, IHC-P, WB Rb Hu, Mm, Rt, B, Pi, Av ab9035
70 kDa Neurofilament Light [2F11] M IHC-Fr, IHC-P, WB Mm Hu, Op ab8970
70 kDa Neurofilament Light [DA2] M ICC, IF, IHC-Fr, WB Mm Hu, Mm, Rt, Ch, C, Pi ab4572
160 kDa Neurofilament Medium P IF, IHC-F, IHC-Fr, IHC-P, WB Rb Hu, Mm, Rt, F, B, Pi, Re, Av ab9034
160 kDa Neurofilament Medium [3H11] M IHC-F, IHC-Fr, IHC-P, WB Mm Hu ab7256
160 kDa Neurofilament Medium [RNF403] M IHC-Fr, WB Mm Hu, Rt ab9271
160 kD Neurofilament Medium antibody [NF-09] (ab7794)
IF - ab7794 at a dilution of 1/1000, staining on rat brain tissue (30µm thick coronal sections) in free floating IHC.
Clonality Applications tested Host Species reactivity Datasheet
M WB, ELISA, IHC-P, IHC-Fr, IF, ICC Mm Ma www.abcam.com/ab7794
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
6 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
200 kDa Neurofilament Heavy P IF, IHC-Fr, IHC-P, WB Rb F, B, Hu, Mm, Pi, Rt ab8135
200 kDa Neurofilament Heavy [NAP4] M ELISA, IHC-F, IHC-Fr, IHC-P, WB Mm Av, Ma ab7257
200 kDa Neurofilament Heavy [RNF402] M IHC-Fr, IHC-P, WB Mm Hu, Rb, Rt, Mm, B, D, Sh,
Gp, Ch, Ha, Mk, X ab3966
200 kDa Neurofilament Heavy [SPM203] M IHC-P, WB Mm Hu ab17879
200kDa + 70kDa Neurofilament [2F11] M IF, IHC, IHC-P, IP, WB Mm Hu ab17114
Peripherin P ELISA, ICC, IF, IHC-F, IHC-P, WB Rb Ma ab7258
Peripherin [2Q135] M ICC, WB Mm Hu, Mm, Rt, C, Pi.
Does not react with Ch ab17999
Peripherin [7C5] M ICC, IHC-P, WB Mm Ch ab4573
Peripherin [8G2] M ELISA, ICC, IHC-F, IHC-P, WB Mm Ma ab7657
Peripherin variant PER56 P IHC-Fr, IHC-P, WB Rb Hu, Mm ab4655
Peripherin variant PER61 P IHC-Fr, IHC-P, WB Rb Hu, Mm ab4646
200 kD Neurofilament Heavy antibody [NF-01] (ab7795)
IF - ab7795 at a dilution of 1/1000, staining in rat brain tissue (30 µm thick coronal sections) on free floating IHC.
Clonality Applications tested Host Species reactivity Datasheet
M WB, ELISA, IHC-P, IHC-Fr, IF, ICC Mm Ma www.abcam.com/ab7795
Cell adhesion proteins
Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Microtubules
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
beta III Tubulin [TU-20] M ICC, IF, IHC-P, IP, WB Mm Ma ab7751
beta III Tubulin [TUJ-1] M ICC, IF, IHC-Fr, WB Mm Hu, Rt ab14545
Doublecortin P IHC-Fr Gp Hu, Mm, Rt ab10293
MAP2 P IF, IHC, WB Ch B, Hu, Mm, Rt ab5392
MAP2 [AP-20] M ICC, WB Mm Mm, Rt, X, B, Q, S ab11268
MAP2 [HM-2] M ICC, IHC, WB Mm Hu, Mm, Rt, B, Ch, Q ab11267
MAP2 [MT-01] M ICC, IF, IP, WB Mm Mm, F, C, Pi ab7756
MAP2a + MAP2b [AP20] M ICC, IF, IHC-P, WB Mm Hu, Rt, Mm, B, Ch, X , Q ab3096
MAP2a + MAP2b [MT-01] M ELISA, IHC-Fr, IHC-P, WB Mm Hu, Mm, F ab8479
MAP5 [3G5] M IF, IHC-P, IHC on primary cultures Mm Hu, Mm, Rt, C.
Does not react with Ch ab3095
Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Regulation
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Thrombospondin 1 [CSI 002-65] M ELISA, IHC, IHC-Fr, IP Mm Hu, B ab23420
Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Thin Filaments
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
MYRIP P Fast track Gt Fast track ab10149 Pep. avail.
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 7Neuroscience > Cell Adhesion Proteins > ECM Proteins
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Agrin [AGR 131] M ICC, IHC, IRMA, WB Mm Mm, Rt ab12362
Agrin [Agr 247] M ICC, IF Mm Mm, Rt ab12364
Agrin [Agr 86] M FACS, ICC, WB Mm Mm, Rt ab12361
Amisyn P Fast track Gt Fast track ab5899 Pep. avail.
Bestrophin P ICC, IHC, IP, WB Rb Hu, Mm, Rt ab14927
Bestrophin M WB Mm Hu, Pi, Mk ab2182
Drebrin P WB Rb Rt, Hu ab11068
Drebrin [M2F6] M IHC-Fr, IHC-P, WB Mm Hu, Mm, Rt, Ch, F, Gp, Mk ab12350
Fetuin A P ELISA, WB Rb Hu ab13980
Laminin P ELISA, IF, IHC-P, RIA Rb Hu ab23753
Laminin P ELISA, WB Ch Hu, Mm, Rt ab14055
Laminin P Dot, IF, IHC-F, IHC-P Rb Ma, Am, Av, Re ab11575
Laminin [A5] M ICC, IHC-Fr, WB Rt Hu, Mm, Ba ab2500
Laminin [LAM-89] M IF, IHC-P Mm Hu, F, Rb.
Does not react with:
Mm, Rt, Ch, D, Gp, Li, Pi, Sh or Sn ab11574
Laminin [MEC5] M IHC-Fr Rt Hu, Mm, Rt ab2466
Laminin 2 alpha [4H8-2] M ELISA, ICC, IF, IP, WB Rt Hu, Mm ab11576
Laminin 5 P IHC-Fr, WB Rb Hu ab14509
Laminin B2 gamma 1 [SPM277] M IF, IHC-P, IP, WB Rt Hu, Mm ab17792
Laminin S [C4] M IP, WB Mm Hu, Rt, B, Pi, Gp, Ch ab3289
67kDa Laminin Receptor P ICC, IF, IHC-P, IP, WB Rb Hu, Mm ab711
Cell adhesion proteins
67kDa Laminin Receptor [MLuC5] M FACS, ICC, IF, IHC-P Mm Hu, Rt ab3099
Mint3 P WB Rb Rt, Mm ab3450 Pep. avail.
NCAM [123C3] M IF, IHC-F, IHC-Fr, IHC-P Mm Rt, Hu ab8077
NCAM [B332 (123A8)] M FACS, IHC-Fr, WB Mm Hu ab8596
NCAM [ERIC-1] M ELISA, IHC-Fr, IP, RIA, WB Mm Hu ab6123
NCAM [H28-123] M AP, IHC-Fr, IM, WB Rt Mm ab19782
NCAM [MEM-188] M FACS, IP, WB Mm Hu ab8233
NCAM [RNL-1] M ICC, IF, IHC-Fr, WB Mm Hu, Mm, Rt ab9018
Nicastrin P WB Rb Hu, Mm ab3444 Pep. avail.
SIRP [MRC OX-41 ] M FACS, IHC-Fr, IHC-P, WB Mm Rt ab9295
SIRP alpha P IHC-P, WB Rb Hu, Mk.
Does not react with Mm ab2971
SIRP alpha P WB Rb Hu, Rt, Mm ab8120 Pep. avail.
67kD Laminin Receptor antibody (ab2508)
IF - staining observed in the hippocampus in the cytoplasm of some astrocytes and neurons using ab2508.
Recommended dilution of antibody is 1:300-1:1000 with overnight incubation at room temperature. Free floating IHC
performed with TSA amplification.
Clonality Applications tested Host Species reactivity Datasheet
P IHC-Fr, Fl, IP, WB Rb Hu www.abcam.com/ab2508
Reelin antibody [142] (ab18569)
IHC-P - ab18569 detecting Reelin immunoreactivity in Cajal-Retzius cells of the mouse cortex at postnatal day 0.
ab18569 was used at 1/1000 (overnight incubation at 4°C). Immunoreactivity was visualized using ABC amplification.
Clonality Applications tested Host Species reactivity Datasheet
M ELISA, ICC, IHC-P, IP Mm Many www.abcam.com/ab18569
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
8 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Cell Adhesion Proteins > ECM Proteins
Target Clonality Applications tested Host Species reactivity Datasheet
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Synaptotagmin P ICC, IP, WB Rb Rt, X ab13260
Synaptotagmin P IF, WB Rb Hu, Rt ab10104
Synaptotagmin P ELISA, WB Ch Hu, B, Mm, Pi, Rt ab8037
Synaptotagmin [ASV30] M ICC, IHC, IP, WB Mm Mm, Rt, X, B, Ch, Rb, Sha ab13259
Synaptotagmin [ASV48] M ICC, IHC, IP, WB Mm Rt, B, Mk, Sha, Mm ab12255
SynCAM P WB Rb Rt ab3910
Syntrophin [1351] M IF, IP, WB Mm Hu, Mm, Rt, Am, Ch, D, Fi ab11425
Syntrophin gamma 2 P ELISA, WB Gt Hu ab15713 Pep. avail.
Tenascin C P WB Ch Hu ab16290
Tenascin C [MTn-12] M AF, Dot, ELISA, IF, IHC, IHC-F,
IHC-Fr, IP, WB Rt Mm ab6346
Reelin antibody [G10] (ab18570)
IHC-P - ab18570 detecting Reelin immunoreactivity in Cajal-Retzius cells of the mouse cortex at postnatal day 0.
ab18569 was used at 1/5000 (overnight incubation at 4°C). Immunoreactivity was visualized using ABC amplification.
NB: Antigen retrieval performed (microwave in citrate buffer pH 6).
Clonality Applications tested Host Species reactivity Datasheet
M WB, IP, ELISA, IHC-Fr, ICC, IHC-P Mm Mm, Rt. Does not react with Hu www.abcam.com/ab18570
Cell adhesion proteins
Neuroscience
Abwire at
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neuroscience
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Target Clonality Applications tested Host Species reactivity Datasheet
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Cathepsin B P ID, WB Sh Hu ab211
Cathepsin B P IHC-Fr, IHC-P Rb Hu ab7670
Cathepsin B [3E1] M IHC-Fr, IHC-P Mm Hu ab7430
Cathepsin D P ELISA, WB Rb Hu ab19555
Cathepsin D P IHC-Fr, IHC-P Rb Hu ab826
Cathepsin D [CTD-19] M ELISA, IHC-F, IHC-P, WB Mm Hu ab6313
Cathepsin D [D101] M IHC-Fr, IHC-P Mm Hu ab7433
Cathepsin G P ELISA, WB Rb Hu ab20725
Cathepsin G P IHC-Fr, IHC-P Rb Hu ab15988
Cathepsin G P WB Sh Hu ab8816
Cathepsin H [1D10] M IHC-Fr, IHC-P, WB Mm Hu ab7432
Cathepsin L P IHC-Fr, IHC-P Sh Hu ab7454
Cathepsin L [33/2] M ELISA, IHC-Fr, WB Mm Hu, Mm, Rt, Mi ab6314
Heparan Sulfate Proteoglycan 2 [CSI 001-74] M AP, ELISA, IHC, IHC-Fr, IP, WB Mm Hu, C ab23418
Heparan Sulfate Proteoglycan 2
[SPM255], prediluted M IHC-P Rt Hu, Mm, B, Pi ab17848
MOSP [CE1] M IF, IHC-Fr Mm Hu, Rt, Mm, F, Ch, Mk, Ca ab3094
Myelin Basic Protein P WB Rb Hu, Mm, Rt ab12355
Myelin Basic Protein P IF, IHC-Fr, IHC-P Rb Hu, Rt ab2404
Myelin Basic Protein [2B5] M ICC, IHC-F, IHC-Fr, IHC-P Mm Hu ab8053
Myelin Basic Protein [12] M AF, ELISA, IF, IHC-Fr, PCC,
RIA, WB Rt Hu, B, Gp, Mm, Rb, Rt, Sh ab7349
Cell adhesion proteins
Myelin Basic Protein [26] M IHC-Fr Mm MBP from most species ab11162
Myelin Basic Protein [B505] M IHC-Fr, IHC-P Mm Hu, Rb, Rt, C, Mk ab8764
Myelin Basic Protein [Clone 2] M ELISA, IHC-Fr Mm Hu, Rt, B, Gp, Rb, Sh ab11159
Myelin PLP [plpc 1] M IF, IHC-Fr, WB Mm Ma ab9311
PMP22 P IHC-P Rb Hu ab15506
PMP22, prediluted P IHC-P Rb Hu ab15507
PMP22 [20-14] M IHC-P Mm Hu ab3278
SORL1 P Fast track Gt Fast track ab22814
Spinesin P WB Gt Mm ab2245
Proteins
Myelin Basic Protein protein (Biotin) ab792
NrCAM antibody (ab24344)
IF - ab24344 (1/300) detects NrCAM on embryonic day 11.5 mouse spinal cord. Floor plate commissurral axons
crossing to the contralateral side of the spinal cord are shown here labeled for NrCAM. Mouse spinal cord was 4%
PFA-fixed and processed on slide for IF.
Clonality Applications tested Host Species reactivity Datasheet
P IF, IHC-F, IHC-P, IHC-FrFl, IP, WB Rb Hu, Mm, Rt www.abcam.com/ab24344
Neuroscience > Cell Adhesion Proteins > Nuclear Proteins
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Galectin 3 P IHC, WB Rb Hu ab2473
Galectin 3 [A3A12] M ELISA, FACS, IF, IHC-Fr, IP, WB Mm Hu, Rt, Mm ab2785
Galectin 7 P IP, WB Rb Mm ab10482
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
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Aggrecan ARGxx [BC-3] M ELISA, IHC-Fr, IHC-P, WB Mm Hu, B, F, D, Gp, H, Pi,
Rb, Rt, Sh ab3773
AMIGO2 P WB Rb Mm, Rt ab16762
CRMP5 [CR-1] M IHC-Fr, WB Rt Hu, Rt, B ab19378
CRMP5 [CR-3] M IHC-Fr, WB Rt Hu, Mm, Rt, B ab19352
EphA1 P ELISA, WB Rb Hu ab5385
EphA1 P I-ELISA, WB Gt Hu ab7036
EphA2 P ELISA, WB Rb Ha, Hu, Mm ab5387
EphA2 P BL, ELISA, ICC, IHC-Fr, WB Gt Mm ab10610
EphA3 P I-ELISA, WB Gt Mm ab7038
EphA3 P ELISA, WB Gt Hu.
Does not react with Mm ab10611
EphA3 [III-A4] M FACS, IP Mm Hu ab19439
EphA4 P ELISA, WB Rb Hu ab5389
EphA4 P I-ELISA, WB Gt Mm ab7039
EphA4 P I-ELISA, WB Gt Hu ab7041
EphA5 P ELISA, WB Rb Hu, Mm ab5397
EphA5 P ELISA, WB Gt Mm, Rt ab10612
EphA6 P ELISA, WB Gt Mm ab10613
EphA7 P ELISA, WB Rb Hu ab5411
EphA7 P ELISA, WB Gt Mm ab10614
Growth and development
EphA8 P ELISA, WB Gt Mm ab10615
EphB1 P ELISA, WB Rb Hu, Mm ab5414
EphB1 P I-ELISA, WB Gt Rt ab7042
EphB1 P Dot, IP Sh Hu ab10406
EphB2 P ELISA, WB Rb Hu, Mm ab5418
EphB2 P Dot, ELISA Gt Mm ab10616
EphB3 P ELISA, WB Gt Mm ab10617
EphB3 P ELISA, WB Gt Hu ab7044
EphB4 P Dot, ELISA, Inhib Gt Mm ab10618
EphB6 P Dot, ELISA Gt Mm ab10619
L1CAM [UJ127] M IF, IHC-P, IP, WB Mm Hu ab3200
L1CAM [UJ12711] M IP, WB Mm Hu ab20148
L1CAM [UJ1814] M IP, WB Mm Hu ab20149
Neuropilin 1 P ELISA, WB Gt Hu ab18130
Neuropilin 1 P IHC-P, WB Rb Rt, Mm ab16786
Neuroserpin P IHC, WB Rb Hu ab16171
NRG1 P WB Rb Hu, Mm ab2994
NRG1 [7D5] M IHC-Fr, IHC-P, IP, WB Mm Rt, Mm ab2369
NRP2 P WB Ch Hu ab15874
Reelin [142] M ELISA, ICC, IHC-P, IP, WB Mm Ma, Av ab18569
Reelin [G10] M ELISA, ICC, IHC-Fr, IHC-P, IP, WB Mm Mm, Rt.
Does not react with Hu ab18570
Robo1 P ELISA, IF, WB Rb Mm ab7279
Robo4 P WB Rb Mm ab10547
Slit1 P WB Rb Mm, Rt ab10984
Slit2 P Fast track Rb Fast track ab7665
Proteins
Robo4 protein ab19112
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Target Clonality Applications tested Host Species reactivity Datasheet
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Axotrophin P WB Ch Hu, Mm, Rt ab13997
Cdk5 P ELISA, WB Rb Hu, Mm, Rt ab19426
Cdk5 [SPM236], prediluted M IHC-P Mm Hu, Mm, Rt ab17875
DYRK1A P IF, IP, WB Sh Hu ab16140
PTPR P WB Rb Hu ab12153
STMN2 P Fast track Gt Fast track ab21190
FOX1A antibody (ab12161)
ICC - ab12161 staining (1/200) in mouse E11 cortical cells cultured for 6 days.
Clonality Applications tested Host Species reactivity Datasheet
P WB, IF, ICC, IHC Rb Hu, Mm www.abcam.com/ab12161
Neuroscience > Growth & Development > Neurotrophins
Growth and development
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Artemin P WB Rb Hu ab1136
BDNF P ELISA, WB Rb Hu ab9793
BDNF [35928.11] M ELISA, WB Mm Hu ab10505
BDNF (Biotin) P ELISA, WB Rb Hu ab12385
BMP2 P Dot, ELISA, WB Rb Hu, Mm, Rt ab14933
BMP2 P ELISA, WB Rb Hu ab17885
BMP2 [65529.111] M I-ELISA, WB Mm Hu ab6285
BMP2 (Biotin) P ELISA, WB Rb Hu ab17597
CNTF P I-ELISA, Neut, WB Gt Rt ab10834
CNTF P ELISA, Neut, WB Rb Rt ab9785
CNTF P ELISA, IHC, WB Ch Hu, Mm, Rt ab17692
CNTF [AS23] M ELISA, IP, WB Mm Hu ab17284
CNTF (Biotin) P ELISA, WB Rb Rt ab12426
GDNF P I-ELISA, Neut, WB Gt Hu ab10835
GDNF P Dot, IHC-Fr, WB Sh Hu ab6206
GDNF P ELISA, IHC, WB Ch Hu, Mm, Rt ab17637
GDNF family Receptor alpha 2 P IHC-Fr, WB Rb Mm, Rt ab6170
GDNF family Receptor alpha 3 P IHC-Fr, WB Rb Mm, Rt ab6171
GDNF family Receptor alpha 3 P WB Rb Hu, Rt, Mm ab8028 Pep. avail.
GDNFR alpha P WB Rb Hu, Rt, Mm ab8026 Pep. avail.
GFR alpha 2 P WB Rb Hu, Mm, Rt ab19146
BDNF antibody (ab6201)
IHC - immunostaining BDNF-containing hippocampal neurons in coronal rat brain sections (30 microns). ab6201 used
at 1/100 dilution.
Clonality Applications tested Host Species reactivity Datasheet
P Dot, ELISA, IHC-Fr, Neut, WB Rb Hu, Rt www.abcam.com/ab6201
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
12 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Growth & Development > Neurotrophins
Target Clonality Applications tested Host Species reactivity Datasheet
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GFR alpha 3 P WB Rb Hu, Mm, Rt ab19135
LANGF Receptor [MC-192] M FACS, IHC-Fr Mm Rt ab6172
Neurotrophin 3 P Dot, ELISA, IHC-Fr, Neut, WB Rb Hu ab6202
Neurotrophin 3 P ELISA, IHC-Fr, IHC-P, WB Gt Hu, Rt ab10334
Neurotrophin 3 (Biotin) P ELISA, WB Gt Hu ab17524
Neurotrophin 4 P ELISA, Neut, WB Gt Hu ab9824
Neurotrophin 4 M ELISA Mm Hu ab9330
Neurotrophin 4 (Biotin) P ELISA, WB Rb Hu ab17888
Neurotrophin 4/5 P Dot, ELISA, IHC-Fr, Neut, WB Rb Hu ab6205
Neurturin P Dot, ELISA, IHC-Fr, WB Sh Hu ab6208
Neurturin P WB Rb Hu ab8061
Neurturin peptide BL ab8393
NGF P Inhib, Dot, ELISA, IHC-Fr, Neut, WB Rb Mm ab6198
NGF [1.A.15] M ELISA Mm Hu ab18167
NGF 2.5S P Dot, Inhib, WB Rb Hu, Mm, Ch ab10515
NGF beta P ELISA, Neut, WB Gt Hu, Mm, Rt ab10837
NGF beta [25623.1] M Dot, ELISA, Inhib Mm ab10513
NRG1 P WB Rb Hu, Mm ab2994
NRG1 [7D5] M IHC-Fr, IHC-P, IP, WB Mm Rt, Mm ab2369
p75 NGF Receptor P Dot, FACS, IF, IHC-Fr, IHC-P, IP, WB Rb Mm, Rt ab8874
p75 NGF Receptor [12A8] M Dot, ICC, IHC-Fr, IP, WB Rt Mm ab8876
Growth and development
p75 NGF Receptor [ME20.4] M EM, ELISA, FACS, ICC, IF, Mm Hu, F, Pi .
IHC-P, Inhib, IP, RIA, WB Does not react with Mm, Rt or Ch ab10495
p75 NGF Receptor [NGFR5] M FACS, IF, IHC-P Mm Hu, Ba, F, Ca, Mk, Rb
Does not react with Mm or Rt ab3125
Pleiotrophin P ELISA, WB Rb Hu ab14025
Pleiotrophin P ELISA, WB Gt Hu ab10849
SPON1 P WB Ch Hu, Mm, Rt, C ab14271
TrkA (phospho Y490) P ICC, IP, WB Rb Hu, Mm, Rt ab1445
TrkA/B [1.A.37] M IP, WB Mm Hu ab18137
TrkB P IHC-Fr Rb Rt ab6180
TrkB P I-ELISA, WB Gt Hu ab10841
Proteins
BDNF protein ab9794
CNTF protein ab9786
GDNF protein ab9790
Neurotrophin 3 protein ab9792
Neurotrophin 4 protein ab9825
Neurturin protein ab9840
NGF beta protein ab9796
TrkA antibody (ab8871)
IF - ab8871 immunostaining in terminals of primary afferent fibers (fibers in the top part of the figure) of the dorsal root
ganglion. Free floating IHC performed on 30um cryostat sections. Primary antibody ab8871 was used at 1/3000 and
incubated overnight at room temperature.
Clonality Applications tested Host Species reactivity Datasheet
P IHC-Fr, IHC-FrFl, IF Rb Rt www.abcam.com/ab8871
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 13Neuroscience > Growth and Development > Notch Pathway
Target Clonality Applications tested Host Species reactivity Datasheet
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ADAM10 P WB Rb Hu ab10956
APH1a P WB Rb Rt, Hu, Mm ab12104 Pep. avail.
APH1a P IF, IP, WB Rb Hu, Mm ab19390
DLL4 P ELISA, IHC-F, IHC-P, WB Rb Hu, Mm ab7280
Jagged 1 P ELISA, FACS, Neut, WB Gt Hu, Rt ab10580
Jagged 2 P Fast track Rb Fast track ab10556
LNX P Fast track Gt Fast track ab4538
MAML1 P Fast track Gt Fast track ab17019 Pep. avail.
Notch1 [A6] M FACS, IHC-P, WB Mm Hu, Mm ab3294
Notch1 (activated) P Co-IP, ICC, IF, IP, WB Rb Hu, Mm ab8925 Pep. avail.
Notch2 (activated) P Fast track Rb Fast track ab8926 Pep. avail.
Notch1 intra P WB Rb Hu.
Does not react with Mm ab8387 Pep. avail.
Notch1 [SPM206], prediluted M IHC-P Mm Hu, Mm ab17843
Notch1 intra + Notch2 intra P Fast track Rb Fast track ab8928 Pep. avail.
Notch 2 intra P WB Rb Hu ab8927 Pep. avail.
NUMB P IF, IHC-P, IM, WB Gt Hu, Mm ab4147 Pep. avail.
NUMB P IP, WB Rb Hu, Mm ab14140 Pep. avail.
NUMBL P Fast track Gt Fast track ab5641 Pep. avail.
PEN2 P IP, WB Rb Hu ab16555
Presenilin 1 P ELISA, IHC-Fr, IHC-P, WB Gt Hu ab7297
Growth and development
Presenilin 1, prediluted P IHC-P Rb Hu ab15508
Presenilin 1 [APS 11] M ELISA, IF, IHC-P, WB Mm Hu, Mm, Rt ab15456
Presenilin 1 [APS 18] M ELISA, IF, WB Mm Hu, Mm, Rt ab15458
Presenilin 2 P ELISA, IHC-Fr, IHC-P Gt Hu ab11148
Presenilin 2 P ELISA, IHC, WB Ch Hu, Mm, Rt ab18041
Presenilin 2 [198C67921] M WB Mm Hu ab13926
Presenilin 2 [APS 26] M ELISA, IF, WB Mm Hu, Mm ab15549
SIAH Interacting Protein P Fast track Gt Fast track ab4276 Pep. avail.
SIAH1 P WB Gt Hu ab2237 Pep. avail.
Neuroscience > Growth and Development > Signal Transduction
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
14-3-3 P IP, WB Rb Hu, Mm, Rt ab9063
14-3-3 P IHC-P, IP, WB Rb Hu, Mm, Rt ab6081
14-3-3 [2Q248] M WB Mm Rt ab14121
14-3-3 [3F7] M IP, WB Mm Hu ab14108
14-3-3 beta P IHC-P, IP, WB Rb Hu, Mm, Rt ab15260
14-3-3 beta P WB Rb Hu, Mm, Rt ab16730
14-3-3 beta [60C10] M ELISA, WB Mm Hu, Mm, Rt ab16859
14-3-3 beta, prediluted P IHC-P Rb Hu, Mm, Rt ab15262
14-3-3 beta + epsilon + zeta [3C8] M WB Mm Hu, Mm, Rt ab12346
14-3-3 beta + zeta P WB Rb Ma, Dm ab14113
14-3-3 beta + zeta [22-IID8B] M ICC, IHC, WB Mm Hu, Mm, Rt, B, D, Mk, Pi, Rb, Sh ab12347
14-3-3 eta + gamma + zeta P ELISA, WB Rb Many ab14124
14-3-3 gamma (acetyl V1) [KC21] M WB Mm Hu ab17005
14-3-3 gamma [3F8] M IP, WB Mm Hu ab14117
14-3-3 sigma [1N6] M IF, IHC-P, IP, WB Mm Hu ab14123
14-3-3 tau [3B9] M IP, WB Mm Hu, Mm, Rt, B ab10439
14-3-3 Binding Motif (phospho S) P ELISA, IHC-P, IP, WB Rb Many ab14127
14-3-3 Binding Motif (phospho S) [3i2] M ELISA, IP, WB Mm Many ab14126
Agrin [AGR 131] M ICC, IHC, IRMA, WB Mm Mm, Rt ab12362
Agrin [Agr 247] M ICC, IF Mm Mm, Rt ab12364
Agrin [Agr 86] M FACS, ICC, WB Mm Mm, Rt ab12361
AKT P WB Ch Hu, Mm, Rt, X , B ab13990
AKT P ICC, IP, WB Rb Hu, Mm, Rt ab6076
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
14 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Growth and Development > Signal Transduction
Target Clonality Applications tested Host Species reactivity Datasheet
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AKT (unmodified S473) [BDI111] M ELISA, WB Mm Hu ab19442
AKT (phospho S473) P IF Rb Hu, Mm ab20488
AKT (phospho T308) P IF, WB Rb Hu ab8933
AKT (phospho T34) P ELISA, WB Rb Hu, Mm, Rt, Rb ab23509
AKT peptide BL ab9041
CrkL P WB Gt Hu, Mm ab10907
CSN7b P WB Rb Hu ab11895
Ctip1 [14B5] M ICC, IF, IHC, IP, WB Mm Hu, Mm, Fi ab19487
Ctip1 [15E3AC11] M ICC, IF, IHC, IP, WB Mm Hu, Mm ab18688
Ctip1 [18B12DE6] M ICC, IF, IHC, IP, WB Mm Hu, Mm ab19489
AKT antibody (ab8805)
IF - ab8805 used at 1/80 on cultured neonatal rat cardiomyocytes that express a nuclear-targeted AKT construct. AKT
staining (green) and actin filaments (red).
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-P, IF, ICC, IP, Rb Hu www.abcam.com/ab8805
Transfected Cell Culture, PCC
Growth and development
AKT (phospho S473) antibody (ab8932)
IF - AKT is phosphorylated on Ser 473 in breast tumor. The staining is much stronger than the weak basal level of
phosphorylation in normal breast. The staining is cytoplasmic, as in normal tissue. The phospho Ser 473 AKT
antibody (ab8932) is used with no pretreatment at a dilution of 1:100.
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-P, IF Rb Hu www.abcam.com/ab8932
AKT (phospho S473) antibody (ab4802)
IF - detection of AKT phospho S473 at a dilution of 1/200 (24h incubation at RT). Perinuclear staining observed in
ventral horn neurons of rat spinal cord (30µm saggital sections).
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-P, IHC-Fr, IF, ICC, IHC Rb Hu, Mm, Rt www.abcam.com/ab4802
AKT (phospho T308) antibody (ab4796)
IHC - ab4796 at a dilution of 1/100 (2 overnight incubations at room temperature; ABC amplification). Cytoplasmic and
nuclear staining observed in rat spinal cord motorneurons (ventral horn) 30µm saggital spinal cord sections.
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC Rb Hu, Mm, Rt www.abcam.com/ab4796
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Target Clonality Applications tested Host Species reactivity Datasheet
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Dab1 P IP, WB Gt Mm ab16674
Dab1 P IF, IHC-Fr, IP, WB Rb Mm ab7522
Dab1 (phospho S491) P WB Rb Hu ab5776
Dab1 (phospho Y198) P WB Rb Hu ab5673
Dab1 (phospho Y220) P WB Rb Hu ab5677
Dispatched P Fast track Gt Fast track ab10142
ELAVL2 + ELAVL3 + ELAVL4 [16A11] M IHC-Fr, WB Mm Hu, Mm, Rt, Fi ab14370
EMX2 P IHC, WB Rb Hu, Mm, Rt ab11849
Fetuin A P ELISA, WB Rb Hu ab13980
FMR1 (Drosophila) [6A15] M ELISA, IF, IP, WB Mm Dm.
Does not react with Hu ab10299
FOXG1 P WB Gt Hu ab3394 Pep. avail.
FOXG1 P IHC-P, WB Rb Hu ab23470
GCNF P IHC-P Rb Hu ab13007
Gemin 1 [2B1] M ELISA, IF, IP, WB Mm Hu, Mm, X ab5831
Gemin 2 [2E17] M ELISA, IF, IP, WB Mm Hu, X ab6084
Gemin 3 [12H12] M ELISA, IF, IP, WB Mm Hu ab10305
Gli1 P IHC-P, IP, WB Rb Hu, Mm ab7523
Gli2 P Fast track Rb Fast track ab7181
Gli2 P Fast track Rb Fast track ab7195
Gli3 P Fast track Rb Fast track ab6050
Growth and development
LIM Kinase P WB Rb Mm ab10561
LIS1 P IP, WB Rb Hu ab2607
LIS1 P WB Gt Mm ab2656 Pep. avail.
MAP4K6 P IHC-P Rb Hu ab13140
NCAM [123C3] M IF, IHC-F, IHC-Fr, IHC-P Mm Rt, Hu ab8077
NCAM [B332 (123A8)] M FACS, IHC-Fr, WB Mm Hu ab8596
NCAM [ERIC-1] M ELISA, IHC-Fr, IP, RIA, WB Mm Hu ab6123
NCAM [H28-123] M AP, IHC-Fr, IM, WB Rt Mm ab19782
NCAM [MEM-188] M FACS, IP, WB Mm Hu ab8233
NCAM [RNL-1] M ICC, IF, IHC-Fr, WB Mm Hu, Mm, Rt ab9018
Neuro D4 P Fast track Gt Fast track ab3940 Pep. avail.
Neuroglobin P ELISA, WB Ch Hu ab14010
NR2E3 P IHC-P Rb Hu ab13081
NRG1 P WB Rb Hu, Mm ab2994
NRG1 [7D5] M IHC-Fr, IHC-P, IP, WB Mm Rt, Mm ab2369
PAX2 P IHC-P, WB Rb Hu ab23799
PAX6 P WB Rb Rt, Sh ab5790 Pep. avail.
PHOX2A P IHC, IP, WB Rb Hu, Mm, Rt ab12046
PHOX2A P Fast track Gt Fast track ab4511
PHOX2B P IHC, IP, WB Rb Rt, Hu, Mm ab12047
PROX1 P ELISA, IHC-Fr Rb Hu, Mm, Rt, Ch, Fi ab11941
RAI3 P ICC, IHC-P Rb Hu ab13274
ROR alpha P WB Rb Hu ab16367
ROR alpha P IHC-P Rb Hu ab13109
ROR beta P IHC-P Rb Hu ab13113
SCP1 P IF Rb Hu, Mm ab15087
SCP1 P IF, IHC-Fr, IHC-P Rb Mm ab15090
Ctip2 antibody [25B6] (ab18465)
IHC - using ab18465 on adult mouse hippocampus.
Clonality Applications tested Host Species reactivity Datasheet
M WB, IP, IHC-P, IHC-Fr, IF, Rt Hu, Mm, Fi www.abcam.com/ab18465
ICC, IHC, ChIP
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
16 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Growth and Development > Signal Transduction
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
SIRP alpha P IHC-P, WB Rb Hu, Mk.
Does not react with Mm ab2971
SIRP alpha P WB Rb Hu, Rt, Mm ab8120 Pep. avail.
SIRP [MRC OX-41 ] M FACS, IHC-Fr, IHC-P, WB Mm Rt ab9295
Slit1 P WB Rb Mm, Rt ab10984
Slit2 P Fast track Rb Fast track ab7665
SOX2 P IF Rb Hu, Mm ab15830 Pep. avail.
SOX6 P IHC, IP, WB Rb Hu, Mm, Rt ab12054
SOX8 P IHC, IP, WB Rb Hu, Mm, Rt ab12055
SOX13 P IHC, IP, WB Rb Hu, Mm, Rt ab12060
SOX14 P IHC, IP, WB Rb Hu, Mm, Rt ab12061
SOX22 P IHC, IP, WB Rb Hu, Mm, Rt ab12062
Sprouty 2 P ELISA, IP, WB Rb Hu ab1043
SynCAM P WB Rb Rt ab3910
Tenascin C P WB Ch Hu ab16290
Tenascin C [MTn-12] M AF, Dot, ELISA, IF, IHC, IHC-F,
IHC-Fr, IP, WB Rt Mm ab6346
TRAF6BP P WB Rb Hu ab22049
VCAM1 [14C3] M IF, IHC-P Mm Hu, Mm ab11514
VCAM1 [1G11B1] M FACS, IA, ICC, IHC-Fr, IP Mm Hu ab7219
VCAM1 [M/K-2] M FuncS, IF, IHC Rt Mm ab19569
Growth and development
VCAM1 [MVCAMA(429)] M FACS Rt Mm ab23807
Zic1 P IHC, IP, WB Rb Hu, Mm, Rt ab12070
Zic2 P IHC, WB Rb Hu, Mm, Rt ab12072
Neuroscience
Abwire at
www.abcam.com/
neuroscience
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Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 17Neuroscience > Neurodegeneration > Alzheimer’s > Amyloid
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
ADAM10 P WB Rb Hu ab10956
AMPK alpha 1 P IP, WB Rb B, Hu, Rt ab3759
Amyloid A Component [mcl], prediluted M IHC-Fr, IHC-P Mm Hu ab7505
Amyloid beta Precursor Protein P ELISA, IHC-Fr, IHC-P, WB Gt Hu ab17468
Amyloid beta Precursor Protein P ICC, IP, WB Rb Hu, Mk ab12268
Amyloid beta Precursor Protein P ICC, IHC-P, IP, WB Rb Hu, Mk ab12269
Amyloid Precursor Protein P ELISA, IHC-P, WB Gt Hu ab17325
Amyloid Precursor Protein P IHC-P, IP, WB Rb Hu, Mk ab11117
Amyloid Precursor Protein P WB Rb Hu, Mm ab2073
Amyloid Precursor Protein P ELISA, IHC-Fr, IHC-P, WB Gt Hu ab2084
Amyloid Precursor Protein (phospho T668) P ICC, IHC-P, IP, WB Rb Hu, Mm, Rt ab17417
Amyloid Precursor Protein [3E9] M IHC-P, WB Mm Hu ab12338
Amyloid Precursor Protein Frameshift Mutant P ELISA, IHC-P, WB Gt Hu ab2085
Amyloid Precursor Protein peptide BL ab7874
APH1a P IF, IP, WB Rb Hu, Mm ab19390
APH1a P WB Rb Rt, Hu, Mm ab12104 Pep. avail.
beta Amyloid 1-40 P ELISA, IHC-Fr, RIA Rb Hu ab16218
beta Amyloid 1-40 P IP, WB Rb Hu, Mm ab16622
beta Amyloid 1-40 P ELISA, IHC-P, WB Rb Hu ab10147
beta Amyloid 1-40 [3H2] M ELISA, IF, IHC-P, WB Mm Hu ab17331
beta Amyloid 1-40 [BAM-10] M IHC-Fr, IHC-P Mm Hu ab7501
beta Amyloid 1-40 [BDI350] M ELISA, ICC, WB Mm Hu ab20068
Neurodegeneration
beta Amyloid 1-42 P ELISA, IHC-P, WB Rb Hu ab10148
beta Amyloid 17-42 P ELISA Rb Hu ab17327
beta Amyloid P ELISA, IHC, WB Ch Hu ab17472
beta Amyloid P IHC Rb Ro ab14220
beta Amyloid P ELISA, WB Rb Hu, Mm ab2539
beta Amyloid [2C8] M IHC, WB Mm Hu, Mm ab12349
beta Amyloid [4G8] M ELISA, IHC-P, IP, WB Mm Hu ab1910
beta Amyloid peptide BL ab3698
CLACP P WB Rb Hu, Mm ab16763
Factor VIII heavy chain [RFFVIIIC/8] M ELISA, WB Mm Hu, Pi.
Does not react with Mm, Rt or D ab6345
Amyloid Precursor Protein antibody [MABDE2B4] (ab12266)
IHC-P- ab12266 detecting APP in Alzheimer’s disease human brain. Plaques are observed in the neuropil. Amyloid
deposits stained by DE2B4 (ab12266) can be seen around some blood vessels.
Clonality Applications tested Host Species reactivity Datasheet
M WB, IP, IHC-P, ICC, Mm Hu, C, Mk, Pi www.abcam.com/ab12266
beta Amyloid antibody [6E10] (ab10146)
IHC-P- using ab1910 [clone 4G8] and ab10146 [clone 6E10]. Stains paraffin - embedded cerebellum.
Clonality Applications tested Host Species reactivity Datasheet
M WB, IP, ELISA, IHC-P Mm Hu www.abcam.com/ab10146
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
18 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Neurodegeneration > Alzheimer’s > Amyloid
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
FE65 P WB Rb Mm ab5668 Pep. avail.
FE65 [4H324] M ICC, IP, WB Mm Hu, Mm, Rt ab17469
Humanin P WB Rb Hu ab16758
Mint1 P WB Rb Rt ab3448 Pep. avail.
Mint3 P WB Rb Rt, Mm ab3450 Pep. avail.
PEN2 P IP, WB Rb Hu ab16555
RAGE P ELISA, IHC-P Gt Hu ab20558
RAGE P IHC-Fr, WB Rb Rt, Mm ab3611
SHC P IP, WB Rb Hu, Mm, Rt ab15039
SHC (phospho Y239 + Y240) P WB Rb Hu ab4890 Pep. avail.
SHC (phospho Y317) P WB Rb Hu, Mm ab15040
Neuroscience > Neurodegeneration > Alzheimer’s > Related targets
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Acrolein P ELISA Rb Acrolein ab15138
Caspase 6 (active) P WB Rb Mm, Rt, Hu ab2326
ADAM17 P Dot, WB Rb Hu, Rt, Mm ab2051 Pep. avail.
ADAM17 P WB Rb Hu, Rt, Pi ab11547
Neurodegeneration
ADAM17 P WB Gt Hu ab13535 Pep. avail.
Als2 P Fast track Gt Fast track ab4155 Pep. avail.
ALS2CR1 P WB Gt Hu ab4123 Pep. avail.
ALS2CR2 P WB Gt Hu ab4122 Pep. avail.
ALS2CR2 P WB Rb Hu, Mm, Rt ab17205
ALS2CR3 P Fast track Gt Fast track ab4200 Pep. avail.
Apolipoprotein E P ELISA, IHC-P, WB Gt Hu ab7620
Apolipoprotein E P ID, IE, RID, WB Rb Mm ab20874
Apolipoprotein E [E6D7] M ELISA, IHC-Fr, IHC-P, IP, WB Mm Hu ab1907
Calpastatin P ELISA, WB Ch Hu ab16423
Calpastatin [2G11D6] M ICC, WB Mm Hu, Rt, C, Pi ab3515
Caspase 6 P WB Rb Hu, Mm, Rt ab2552
Caspase 6 P ELISA, WB Rb Hu, Mm, Rt ab18520
Caspase 6 P WB Rb Hu ab19920
Caspase 6 [3F51] M IHC-P, IP, WB Mm Hu ab17866
Caspase 6 [3F52] M IHC-P, IP, WB Mm Hu ab17822
Caspase 6 [6CSP01 (7165)] M IP Mm Hu ab3245
Caspase 6 [6CSP03] M WB Mm Hu ab4062
CCKAR P WB Rb Hu ab14441
Drebrin P WB Rb Rt, Hu ab11068
Drebrin [M2F6] M IHC-Fr, IHC-P, WB Mm Hu, Mm, Rt, Ch, F, Gp, Mk ab12350
ERAB P ELISA, IF, IHC-P, WB Rb Hu ab17298
ERAB [5F3] M Dot, ELISA, IF, IHC-Fr, IHC-P, WB Mm Hu ab10260
Fyn P ELISA, WB Gt Hu ab802 Pep. avail.
ApoE antibody [D6E10] (ab1906)
IHC-P - ab1906 reactivity with Apo E of vascular amyloid beta in a Down Syndrome tissue section.
Clonality Applications tested Host Species reactivity Datasheet
M WB, IHC-P, IHC-Fr Mm Hu www.abcam.com/ab1906
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Target Clonality Applications tested Host Species reactivity Datasheet
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Fyn P WB Rb Hu, Mm ab13955
Fyn [1S] M IHC-P Mm Hu, Rt, Mm ab3116
Fyn [FYN-01] M ICC, IP, WB Mm Hu, Mm ab1881
PHF2 P WB Rb Hu ab1138
Synuclein (alpha) P H, ICC, IHC, IHC-Fr, IHC-P, WB Sh Hu ab6162
Synuclein (alpha) P IHC-P Rb Hu, Rt ab15530
Synuclein (alpha) P ICC, WB Gp Hu, Mm, Rt, B ab16784
Synuclein (alpha) (phospho Y125) P Fast track Rb Fast track ab10789 Pep. avail.
Synuclein (alpha) [4B12] M Dot, ELISA, IHC-Fr, IHC-P, WB Mm Hu.
Does not react with Mm or Rt ab1904
Synuclein (alpha) [4D6] M ELISA, IHC-Fr, IHC-P, WB Mm Hu, Mm, Rt ab1903
Synuclein (beta) P ICC, IHC-Fr, IHC-P, WB Rb Hu ab6165
Synuclein (beta) P IHC-Fr, IHC-P Sh Hu ab6163
Synuclein (beta) P WB Ch Hu ab16420
Synuclein (beta) P IHC-P Rb Hu, Rt ab15532
Synuclein (gamma) P IHC, IHC-Fr, IHC-P, WB Rb Hu, Rt ab6169
Synuclein (gamma) P IHC-Fr, IHC-P, WB Rb Hu, Rt ab6176
Synuclein (gamma) P IHC-P, WB Rb Hu, Rt ab15534
Ubiquitin P ELISA, IF, IHC-F, IHC-Fr,
IHC-P, IP, WB Rb Hu, Rt, H, Mm, B ab7780
Ubiquitin P ELISA, WB Rb Y ab14372
Ubiquitin P WB Ch Hu ab19310
Neurodegeneration
Ubiquitin [10C2-2] M AP, ELISA, IHC-Fr, IHC-P, WB Mm All ubiquitinated proteins ab411
Ubiquitin [1B4-UB] M ELISA, FACS, IHC-Fr, IHC-P, WB Mm Hu, B ab122
Ubiquitin antibody (ab6309)
IF - P23H mutant cells immunostained with ab6309 (1/500 dilution) showing co-localization of mutant aggregated
protein with ubiquitin.
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-Fr, IA, IF Rb C, Sc www.abcam.com/ab6309
Neuroscience > Neurodegeneration > Alzheimer’s > Proteases
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
BACE1 P IHC-P Gt Hu ab11028
BACE1 P WB Rb Hu, Rt, Mm ab2077 Pep. avail.
BACE2 P WB Rb Hu, Rt, Mm ab8025 Pep. avail.
BACE peptide BL ab5857
Cathepsin H [1D10] M IHC-Fr, IHC-P, WB Mm Hu ab7432
Nicastrin P WB Rb Hu, Mm ab3444 Pep. avail.
Presenilin 1 P ELISA, IHC-Fr, IHC-P, WB Gt Hu ab7297
Presenilin 1, prediluted P IHC-P Rb Hu ab15508
Presenilin 1 [APS 11] M ELISA, IF, IHC-P, WB Mm Hu, Mm, Rt ab15456
Presenilin 1 [APS 18] M ELISA, IF, WB Mm Hu, Mm, Rt ab15458
Presenilin 2 P ELISA, IHC, WB Ch Hu, Mm, Rt ab18041
Presenilin 2 P ELISA, IHC-Fr, IHC-P Gt Hu ab11148
Presenilin 2 [198C67921] M WB Mm Hu ab13926
Presenilin 2 [APS 26] M ELISA, IF, WB Mm Hu, Mm, Rt ab15549
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20 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Neurodegeneration > Alzheimer’s > Tangles & Tau
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
14-3-3 tau [3B9] M IP, WB Mm Hu, Mm, Rt, B ab10439
Casein Kinase 1 delta P ELISA, IHC-P Gt Hu ab10877
ERK1 P IHC-P, IP, WB Rb Hu, Rt, Mm ab7947 Pep. avail.
ERK1 P ELISA, IP, WB Rb Hu, Rb, Rt, Mm, C, Pi ab9363
ERK1 (HRP) P ELISA, IP, WB Rb Hu, B, Mm, Pi, Rb, Rt ab9364
ERK1 + ERK2 (phospho T185 + T202) P WB Rb Hu ab4819 Pep. avail.
ERK1 + ERK2 (phospho T185 + T202) (FITC) P FACS, IHC-Fr, WB Rb Hu ab4820
ERK1 + ERK2 (phospho T202/183 + Y204/185) P WB Rb Hu, Mm, Rt ab16869
ERK1 + ERK2 (phospho T202 + Y204) P IF Rb Hu, Mm, Rt ab20490
ERK1 + ERK2 P IP Sh Hu, Rt ab16573
ERK1 + ERK2 P WB Rb Hu, Mm, Rt, B ab17942
GSK3 (alpha + beta) (phospho Y216 + Y279) P Dot, ELISA, WB Rb Hu, Mm, Rt ab4797
GSK3 (alpha + beta) P IHC-P, WB Rb Hu, Mm, Rt, Ch, Mk ab15314
GSK3 (alpha + beta) [1H8] M ELISA, WB Mm Hu, Mm, Rt, Am ab17059
Neurofibrillary Tangle P IHC-Fr, IHC-P, WB Rb Hu ab2076
Neurofibrillary Tangle P ELISA, IHC-P, WB Rb Hu ab11093
PEN2 P IP, WB Rb Hu ab16555
Pin1 P WB Rb Hu ab12107 Pep. avail.
Prealbumin P DID, Ie, RID, RIe Sh Hu, B, F, Ch, D, Gt, Gp, H,
Mm, Pi, Rb, Rt ab9015
Prealbumin P IHC, RID Rb Hu, B, F, D, H ab16006
Prealbumin P ELISA Gt Hu ab15007
Neurodegeneration
Tau (phospho S199) P WB Rb Hu ab4749 Pep. avail.
Tau (phospho S199 + S202) P WB Rb Hu ab4864
Tau (phospho S202) P IHC-Fr, WB Rb Hu ab4839 Pep. avail.
Tau (phospho S208) P WB Rb Hu ab10892 Pep. avail.
Tau (phospho S214) P WB Rb Hu ab4846 Pep. avail.
Tau (phospho S214) P Fast track Rb Fast track ab10891 Pep. avail.
Tau (phospho S356) P WB Rb Hu ab4857 Pep. avail.
Tau (phospho S262) P WB Rb Hu ab4856 Pep. avail.
Tau (phospho S396) P WB Rb Hu ab4858 Pep. avail.
Tau (phospho S400) P WB Rb Hu ab4859 Pep. avail.
Tau (phospho S404) P WB Rb Hu ab4860 Pep. avail.
Tau (phospho S409) P WB Rb Hu ab4861 Pep. avail.
Tau (phospho S422) P WB Rb Hu ab4862 Pep. avail.
Tau (phospho T181) P WB Rb Hu ab4748 Pep. avail.
Tau (phospho T212) P WB Rb Hu ab4842 Pep. avail.
Tau (phospho T217) P WB Rb Hu ab4851 Pep. avail.
Tau (phospho T231) P WB Rb Hu ab4855 Pep. avail.
Tau P IHC-P, WB Gt Hu ab11107
Tau P IHC-F, WB Rb Hu ab22690
Tau P IF, IHC-Fr, IHC-P Rb Hu ab8763
Tau [T1] M WB Mm Hu, Mm, Rt, B ab12354
Tau [Tau] M IHC-Fr, IHC-P Mm Ch, B, Hu, Mk.
Does not react with Mm or Rt ab8739
Tau [TAU-5] M IHC-Fr, IHC-P, WB Mm Hu ab3931
Tau antibody (ab4841)
IF - Transgenic C. elegans first larval stage nematode expressing human wild type Tau GFP (green) and stained with
ab4841 (red). Neurons of the head, dorsa and ventral cords and tail region display phosphorylated Tau.
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-Fr, IHC (no paRtffin) Rb Hu www.abcam.com/ab4841
whole animals
Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM) 21Neuroscience > Neurodegeneration > Alzheimer’s > Tangles & Tau
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Ubiquitin P IA, IF, IHC-Fr, WB Rb C, Sc ab6309
Ubiquitin P ELISA, IF, IHC-F, IHC-Fr,
IHC-P, IP, WB Rb Hu, Rt, H, Mm, B ab7780
Ubiquitin P ELISA, WB Rb Y ab14372
Ubiquitin P WB Ch Hu ab19310
Ubiquitin [10C2-2] M AP, ELISA, IHC-Fr, IHC-P, WB Mm All ubiquitinated proteins ab411
Ubiquitin [1B4-UB] M ELISA, FACS, IHC-Fr, IHC-P, WB Mm Hu, B ab122
Neuroscience > Neurodegeneration > Huntington’s
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
HAP40 P IP, WB Rb Mm ab1139
HAP40 P ELISA, WB Rb Hu ab1400
HIPPI P WB Rb Hu ab5205
Huntingtin [1A771] M WB Mm Many ab13583
Huntingtin [HDA3E10] M IF, IHC-Fr, IP, WB Mm Hu, Rt, Mm ab7668
Huntingtin Interacting Protein HIP1 [4B10] M WB Mm Hu ab5402
Huntingtin Interacting Protein HIP1
[4B107], prediluted M IHC-P Mm Hu.
Neurodegeneration
Does not react with Mm ab11841
Huntingtin Interacting Protein 2 P ELISA, WB Gt Hu ab21728
Neuroscience > Neurodegeneration > Parkinson’s > Related targets
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
ALDH1A1 P WB Gt Hu, Mm.
Does not react with Rt ab9883 Pep. avail.
APH1a P WB Rb Rt, Hu, Mm ab12104 Pep. avail.
APH1a P IF, IP, WB Rb Hu, Mm ab19390
CCKAR P WB Rb Hu ab14441
DORFIN P Fast track Gt Fast track ab3997 Pep. avail.
DORFIN P Fast track Rb Fast track ab10889
ALDH1A1 antibody (ab24343)
IF - staining of ALDH1A1-containing neurons in adult mouse brain sections using ab24343.
Clonality Applications tested Host Species reactivity Datasheet
P IHC-Fr, IHC-FrFl Rb Mm www.abcam.com/ab24343
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
22 Neuroscience resources: www.abcam.com/neuroscienceNeuroscience > Neurodegeneration > Parkinson’s > Related targets
Target Clonality Applications tested Host Species reactivity Datasheet
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PGP95 P WB Gt Hu ab11145
PGP95 P IHC-Fr Gp Hu, Mm, Rt ab10410
PGP95 P IHC-P Rb Hu ab15503
PGP95 [13C4 / I3C4] M IF, IHC-F, IHC-Fr, IHC-P Mm Hu, Rt, Gp ab8189
PGP95 [31A3] M ELISA, IHC-P, WB Mm Hu, Rt ab20559
PINK1 P IHC-P, WB Rb Hu, Mm, Rt ab23707
SIAH1 P WB Gt Hu ab2237 Pep. avail.
Synphilin 1 P IHC-Fr, IHC-P, WB Rb Hu, Mm, Rt ab6179
Synphilin 1 P ELISA, IHC-P, WB Gt Hu ab11106
PGP9.5 antibody (ab10404)
IF - ab10404 at a dilution of 1/1000, detecting PGP9.5 in cortical neurons in rat brain tissue sections prepared for free
floating IHC (4% PFA fixed, 30µm thick coronal sections).
Clonality Applications tested Host Species reactivity Datasheet
P WB, IHC-Fr, IF Rb Hu, Mm, Rt, Pi www.abcam.com/ab10404
Neurodegeneration
Neuroscience > Neurodegeneration > Parkinson’s > Parkin / PARK
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
PARK7 P WB Gt Hu, Mm ab4150 Pep. avail.
PARK7 [malphaDJ-1/E219] M ICC, WB Mm Hu, Fi.
Does not react with Mm ab11251
Parkin P IHC-Fr, WB Rb Hu, Rt ab5667 Pep. avail.
Parkin P Dot, ELISA, IHC-Fr, IHC-P, WB Rb Hu, Rt ab6177
Parkin P ELISA, IHC-P, WB Gt Hu ab7296
Parkin antibody (ab15494)
IHC - ab15494 staining Parkin in Alzheimer’s brain (FFPE-sections).
Clonality Applications tested Host Species reactivity Datasheet
P IHC-P Rb Hu, Mm, Rt www.abcam.com/ab15494
Neuroscience > Neurodegeneration > Parkinson’s > Synuclein
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
DORFIN P Fast track Rb Fast track ab10889
DORFIN P Fast track Gt Fast track ab3997 Pep. avail.
HMGB1 [4C3] M WB Mm Hu, Mm, Rt, C, Pi ab11354
HMGB1 [HAP465] M ELISA, WB Mm Hu, Mm, Rt, Ch, D ab12029
Synphilin 1 P ELISA, IHC-P, WB Gt Hu ab11106
Synphilin 1 P IHC-Fr, IHC-P, WB Rb Hu ab6179
Synuclein (alpha) P ICC, WB Gp Hu, Mm, Rt, B ab16784
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Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
Synuclein (alpha) P IHC-P Rb Hu, Rt ab15530
Synuclein (alpha) P H, ICC, IHC, IHC-Fr, IHC-P, WB Sh Hu ab6162
Synuclein (alpha) (phospho Y125) P Fast track Rb Fast track ab10789 Pep. avail.
Synuclein (alpha) [4B12] M Dot, ELISA, IHC-Fr, IHC-P, WB Mm Hu.
Does not react with Mm or Rt ab1904
Synuclein (beta) P IHC-P Rb Hu, Rt ab15532
Synuclein (beta) P WB Ch Hu ab16420
Synuclein (beta) P IHC-Fr, IHC-P Sh Hu ab6163
Synuclein (beta) P ICC, IHC-Fr, IHC-P, WB Rb Hu ab6165
Synuclein (gamma) P IHC, IHC-Fr, IHC-P, WB Rb Hu, Rt ab6169
Synuclein (pan) P IHC-P, WB Rb Hu, Rt ab15534
Synuclein (pan) P IHC-Fr, IHC-P, WB Rb Hu, Rt ab6176
VCP [5] M IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt ab11433
HMGB1 (ab11972)
ICC- labeling of HMGB1 (red) in HeLa cells using ab11972 (1/50). DNA is stained with DAPI (blue).
Clonality Applications tested Host Species reactivity Datasheet
P IF, WB Rb Hu www.abcam.com/ab11972
Neurodegeneration
alpha Synuclein [4D6] (ab1903)
IHC-P - ab1903 stains Lewy Bodies in a substantia nigra neuron.
Clonality Applications tested Host Species reactivity Datasheet
M ELISA, WB, IHC-P, IHC-Fr Mm Hu, Mm, Rt www.abcam.com/ab1903
Neuroscience > Neurodegeneration > Prions
Target Clonality Applications tested Host Species reactivity Datasheet
www.abcam.com/...
67kDa Laminin Receptor P ICC, IF, IHC-P, IP, WB Rb Hu, Mm ab711
67kDa Laminin Receptor [MLuC5] M FACS, ICC, IF, IHC-P Mm Hu, Rt ab3099
Fyn P WB Rb Hu, Mm ab13955
Fyn P ELISA, WB Gt Hu ab802 Pep. avail.
Fyn [1S] M IHC-P Mm Hu, Rt, Mm ab3116
Fyn [FYN-01] M ICC, IP, WB Mm Hu, Mm ab1881
Prion protease resistant protein 27-30 P ELISA, IHC-P, WB Gt Hu ab7303
Prion protein PrP P ELISA, WB Mm Hu, B ab22366
Prion protein PrP P ELISA, WB Rb Hu, Mm, B ab703
Prion protein PrP P Dot, ELISA, IHC, WB Gt Hu, B, Sh, Ha ab6664
Prion protein PrP [1E5 / G6] M ELISA, WB Mm Hu, B ab2879
Prion protein PrP [1E5 / G6] M ELISA, WB Mm Hu, B ab3408
Prion protein PrP [3B8 / D5] M ELISA, WB Mm C, Sh ab2881
Prion protein PrP [7D9] M ELISA, IHC, IHC-F, IHC-P, WB Mm Mm, B, De, El, Ha, Hu, Rt ab14219
Prion protein PrP [WD3C7] M ELISA, IP, WB Mm B ab13643
Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
24 Neuroscience resources: www.abcam.com/neuroscienceYou can also read
