Neuroscience Antibodies & Protocols

 
 
Neuroscience Antibodies & Protocols
Neuroscience Antibodies & Protocols
(U.S.A. & European edition) 2006




www.abcam.com
Neuroscience Antibodies & Protocols
Contents
                     Welcome to Abcam
Catalogue contents




                     About Abcam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1         The team . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
                     Neuroscience at Abcam . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2             Benefits of an Abcam account . . . . . . . . . . . . . . . . . . . . . . . .3
                       Neuroscience Abwire . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2             AbreviewsSM and Abcam AbpointsSM . . . . . . . . . . . . . . . . . . . .3

                     Abbreviations
                     Species key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5     Applications key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5

                     Neuroscience antibody categories
                     Cell adhesion proteins                                                                         Oxytocin & Vasopressin . . . . . . . . . . . . . . . . . . . . . . . . . .30
                       Cytoskeletal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6        Thyroid Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30
                       ECM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8   Neuronal markers
                       Membrane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10           Glia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31
                       Nuclear . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10        Neural Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33
                     Growth & development                                                                           Neuron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35
                       Axonal Guidance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11            Neurotransmission
                       Neurogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11           Calcium Signaling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
                       Neurotrophins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12          Intracellular Signaling . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
                       Notch Pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13            Neurotransmitters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .47
                       Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14              Neuropeptides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .50
                     Neurodegeneration                                                                              Nitric Oxide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52
                       Alzheimer’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18        Pharmacological Tools . . . . . . . . . . . . . . . . . . . . . . . . . . .53
                       Huntington’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22         Receptors & Channels . . . . . . . . . . . . . . . . . . . . . . . . . . .53
                       Parkinson’s . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22        Secretory Vesicles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .59
                       Prions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24     Transporters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .61
                       Related Targets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25          Sensory pathways
                     Neuroendocrinology                                                                             Hearing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
                       GH Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26            Nociception . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
                       Gonadotrophic Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26               Olfaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
                       HPA Axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27       Touch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
                       Obesity & Metabolism . . . . . . . . . . . . . . . . . . . . . . . . . . .28                 Vision . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63

                     Technical help
                        Neuroscience resources at Abcam . . . . . . . . . . . . . . . . .64                          Neuroscience protocols and tips . . . . . . . . . . . . . . . . . . .66
                        Product datasheet guide . . . . . . . . . . . . . . . . . . . . . . . . .65                  Neuroscience signaling pathway diagrams . . . . . . . . . . .85

                     Ordering and contact details
                     Contact details . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89      Required Information for ordering . . . . . . . . . . . . . . . . . . . .89
                     Ways to order . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89        Abcam’s terms and conditions . . . . . . . . . . . . . . . . . . . . . . .90

                     Coming soon
                     New Neuroscience antibodies . . . . . . . . . . . . . . . . . . . . . . .91

                     Target index
                     Target index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92




                                                                          Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                                                                                                  Neuroscience resources: www.abcam.com/neuroscience
Neuroscience Antibodies & Protocols
Welcome to Abcam
About Abcam
                       Abcam, located in Cambridge, U.K. and Cambridge, MA, U.S.A., was founded in 1998 by Dr. Jonathan
                       Milner, then a researcher at Cambridge University, U.K.:

                         “Like many life science researchers, I was frustrated by the time it took to locate and select
                       antibodies essential for my research. This was largely due to poor information and out-of-date
                       catalogs from the vast range of suppliers who were spread across many countries. In some cases, I
                       also experienced difficulties with companies whose products were unreliable and whose customer
                       service was slow and unhelpful. My vision was to build a company that offered reliable cutting-edge




                                                                                                                                 Welcome to Abcam
                       products and great customer service.”

It was a tough vision - Abcam was created to sell the best antibodies in the world with the most comprehensive, honest and
up-to-date datasheets, fast delivery, helpful customer service and comprehensive technical support.


Seven years on and with thousands of products across our range, Abcam ships to
scientists in over 55 countries around the world. Abcam is committed to the
following fundamental principles that have seen us become the first choice
for thousands of life-scientists throughout industry and academia:

•   Quality of products and datasheets
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Comprehensive
We have a policy of honesty - our customers know everything that we know about
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posted on the datasheet. To achieve exceptional levels of quality for our customers
we provide:

•   Comprehensive datasheets.
•   Customers’ AbreviewsSM of our products .
•   Product-specific protocols used by our customers.
•   Customers’ technical questions and our answers for each product.
•   Product information and new products updated daily.                                          ...all at www.abcam.com!

Helpful
Our Technical Support and Customer Service departments are full of scientists that have many years of experience working
with the types of products that we supply to our customers.
We provide continuous order progress updates, so that you always know what is happening with your order and when you
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Abcam demonstrated excellent year-on-year growth in overseas sales between 2002 and 2004 with 84%
of sales during these three years coming from overseas customers. The award is positive proof of the
company's outstanding success as a customer-focused international business.




Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM)                                          1
Neuroscience Antibodies & Protocols
Free services
                       The World’s Antibody Gateway search engine
                       If we do not have the product that you are looking for use this service to search all online catalogs of other antibody suppliers.
                       Find the “WAG” at:
                       www.abcam.com/antibodygateway

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                       Directly search your choice of Abcam, GenBank, Google, LocusLink, OMIM, PubMed, SWISSProt. The toolbar sits within your
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                       Fast
                       We have developed web-based systems that enable us to quickly identify cutting-edge products, make them rapidly available
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                       We are pleased to be able to offer next-day delivery to all major cities as well as same day delivery to customers in Cambridge
                       U.K. and Cambridge MA, U.S.A.


                       Neuroscience at Abcam
                       Our range of over 2,000 Neuroscience primary antibodies has a breadth and depth that is hard to beat. Further more, we
                       collaborate with leading academics to make the Abcam range one of the best in the world!

                       The Neuroscience Abwire
                       Our Neuroscience Abwire web page is full of exclusive articles, product browsing tools, conference and publication information
                       and specialist protocols. Visit today for cup-to-date information in this rapidly progressing field.

                       Look out for new Neuronal Marker IHC Galleries, Neurodegeneration and Neurotransmission signaling pathway diagrams and
                       Neuroscience Product Locator tools (to name but a few).

                       Visit: www.abcam.com/neuroscience for more.

                       The Neuroscience team
                       Abcam has a specialized team working on sourcing and testing the best Neuroscience antibodies available. Our background in
                       the neurosciences is very strong to better serve our customers. Members include:


                                             Technical Support                                                          Sarah and Bill help customers
                                             Sarah Mardle (PhD King’s College, University of London, U.K.)              who have enquiries about, or
                                             Technical Support Manager (U.K.)                                           problems with, Abcam
                                                                                                                        antibodies using their extensive
                                                                                                                        PhD and postdoctoral laboratory
                                                                                                                        experience.They also:

                                                                                                                        • Attend conferences to keep
                                                                                                                          up-to-date with antibody
                                             Bill Campbell (PhD Brown University, U.S.A.)                                 techniques and research
                                             Technical Support Manager (U.S.A.)
                                                                                                                        • Source new protein targets

                                                                                                                        • Source novel techniques
                                                                                                                          using antibodies

                                                                                                                        • Build collaborations with
                                                                                                                          academics.




                                                            Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                   2                                                                Neuroscience resources: www.abcam.com/neuroscience
Neuroscience at Abcam
The Neuroscience team

                     Business Development
                     Sabrina Edmonds (PhD University of Cambridge, U.K.)
                     Business Development Manager for Neuroscience

                     Sabrina is responsible for sourcing new and exciting protein targets to generate antibodies against by
                     attending conferences, forging collaborations with academics and by reading current literature. She is




                                                                                                                                      Welcome to Abcam
                     the main contact for academics who are interested in licensing their neuroscience antibodies for sale
                     through Abcam.

                     Marketing
                     Rhian Hayward (PhD University of Oxford, U.K.)
                     Neuroscience Marketing Manager

                     Rhian is responsible for marketing Abcam’s Neuroscience range to our customers worldwide. She
                     ensures that Abcam supports many Neuroscience community activities through conference
                     sponsorships, informative marketing materials e.g. signalling pathways (see page 83), the
                     Neuroscience Abwire and more.

Suggestions or comments: Email the team at neuroscience@abcam.com


Benefits of an Abcam Account
Take full advantage of all our online Neuroscience resources by opening an account.
• Earn Abcam AbpointsSM
• Buy quickly and efficiently online.
• Customise your antibody updates. We can notify you by email of new and updated antibodies related directly to the
  protein families which interest you.


AbreviewsSM
Our unique system for enabling our customers to feedback to you and us about the performance of our primary antibodies. It is
important to know how our antibodies perform under different conditions and that they are working as expected. We encourage
this feedback (positive and negative) by awarding AbpointsSM for each Abreview:

AbreviewTM Action                 Points     Description

Submit an Abreview                  50       Each unique combination of antibody, application and sample species that you
                                             review, earns you Abcam AbpointsSM, e.g. if you use one of our antibodies in
                                             WB on Human and Mouse samples and submit an Abreview for both these
                                             combinations, then you will receive 50 Points for each one.

Submit an Abreview                 200       As for “Submit an Abreview” but for an antibody that has not yet been tested in
(untested application /                      that particular species or application.
species)

Submit an image with your          100       If you submit an image to accompany any of your Abreviews, then you will
Abreview                                     receive extra Points when it is published with your Abreview. For Abreview and
                                             image publication criteria, please see the Abreviews section of our website.

Fast Track Abreviews               950       Be the 1st researcher to submit conclusive positive or negative data (through
bonus                                        Abreviews see below) about one of our Fast Track antibodies and earn this bonus
                                             (in addition to the Abcam Points that you will earn for submitting your Abreview).


Customers’ Abreviews are posted on the product datasheets for others to browse. You can contact the reviewer to ask further
questions too!



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                       your interests there.

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                                                                                         latest at
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                   4                                                               Neuroscience resources: www.abcam.com/neuroscience
Abbreviations
Species key
Key    Species                             Key    Species                             Key     Species

Many wide range of species                 Fe     Ferret                              Pi      Pig
                                           Fi     Fish                                P       Plants
At     Arabidopsis thaliana                Gt     Goat                                Q       Quail
Am     Amphibian                           G      Goose                               Rb      Rabbit
Av     Avian                               Gp     Guinea pig                          Rt      Rat
Ba     Baboon                              Ha     Hamster                             Re      Reptiles
Bu     Burkholderia spp.                   H      Horse                               Ro      Rodents
Ca     Cat                                 Hu     Human                               Sc      Sacchromyces cerevisiae
Ce     Caenorhabditis elegans              In     Insect                              S       Salamander
Ch     Chicken                             K      Kangaroo                            Sha     Shark
C      Cow                                 Li     Lizard                              Sh      Sheep
De     Deer                                Mm     Mouse                               Sn      Snake
D      Dog                                 Ma     Mammals                             X       Xenopus laevis
Dm     Drosophila melanogaster             Mi     Mink                                Y       all Yeast




                                                                                                                                     Abbreviations
El     Elk                                 Mk     Monkey
Ec     Escherichia coli                    Op     Opossum


Applications key
Key           Applications                                      Key            Applications

AF            Acetone fixed                                     IHC-P          Immunohistochemistry (Formalin-fixed
Agg           Agglutination                                                    paraffin-embedded sections)
AI            Adhesion inhibition                               IM             Immunomicroscopy
AP            Affinity purification                             Inhib          Inhibition assay
BL            Blocking                                          IP             Immunoprecipitation
CCIe          Counter current                                   IRMA           Immunoradiometric assay
              immunoelectrophoresis                             ISH            In situ hybridization
ChIP          Chromatin immunoprecipitation                     Mct            Microcytotoxicity testing
Conjugation   Conjugation                                       Neut           Neutralizing
DID           Double immunodiffusion                            P              Purification
Dot           Dot blot                                          PA             Prothrombin assay
EC            Experimental control                              PCC            Primary cell culture
EIA           Enzyme immunoassay                                PCR            Polymerase chain reaction
ELISA         ELISA                                             RIA            Radioimmunoassay
EM            Electron microscopy                               RID            Radial immunodiffusion
EMSA          Electrophoretic mobility shift assay              RIe            Rocket immunoelectrophoresis
FACS          Fluorescence activated cell sorting               RImm           Radial immunodiffusion
FC            Flow cytometry                                    RipA           Radioimmunoprecipitation assay
FuncS         Functional studies                                SB             Southern blot
GSA           Gel supershift assays                             TCC            Transfected cell culture
H             Histology                                         TLC            Thin layer chromatography
I-ELISA       Indirect ELISA                                    WB             Western blotting
IA            Immunoassay
IB            Immunoblotting                                    Other
ICC           Immunocytochemistry                               Fast Track     Application and species data pending
ID            Immunodiffusion                                   Pep. avail.    Peptide available
Ie            Immunoelectrophoresis
IF            Immunofluorescence
IHC           Immunohistochemistry
IHC-F         Immunohistochemistry (Formalin fixed sections)
IHC-Fr        Immunohistochemistry (Frozen sections)


Many of the images in this catalog have been supplied by Abcam’s collaborators in the Neuroscience field. We wish to thank all
these contributors and we look forward to working with you in the future!




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Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments

                             Target                                  Clonality   Applications tested                     Host      Species reactivity               Datasheet
                                                                                                                                                                    www.abcam.com/...

                             GARP (truncated)                           P        WB                                      Rb        Rt, B                             ab15094
                             GFAP                                       P        IF, IHC-Fr                              Ch        Hu, Mm, Rt, F, C                   ab4674
                             GFAP                                       P        IF, IHC-F, IHC-P, IP, PCC, WB           Rb        F, B, Hu, Mm, Pi, Rt               ab7260
                             GFAP                                       P        IF, IHC-F, IHC-Fr, IHC-P                Rb        Hu, Rt, B                          ab7779
                             GFAP [2A5]                                 M        IF, IHC-F, IHC-P, PCC, WB               Mm        Ma                                 ab8136
                             GFAP [6F2]                                 M        IHC-Fr, IHC-P, IM,
                                                                                 TEM immunogold labeling, WB             Mm        Hu                                  ab8975
                             GFAP [GF-01]                               M        ICC, IHC-Fr, IHC-P, IP, WB              Mm        Hu, F, Pi
                                                                                                                                   Does not react with Mm or Rt        ab7806
                             GFAP (phospho T7) [YC10]                   M        ICC, WB                                 Mm        Hu, C, Pi
                                                                                                                                   Does not react with Mm or Rt       ab12340
                             Internexin alpha                           P        ICC, IHC-Fr, WB                         Rb        Hu, Mm, Rt, C, F                   ab22038
                             Internexin alpha [1D2]                     M        ICC, IHC-P, WB                          Mm        Hu, Rt                             ab22039
                             Internexin alpha [2E4]                     M        ICC, IHC-Fr, IHC-P, WB                  Mm        Hu, Rt                             ab22040
                             Laminin                                    P        ELISA, IF, IHC-P, RIA                   Rb        Hu                                 ab23753
                             Laminin                                    P        ELISA, WB                               Ch        Hu, Mm, Rt                         ab14055
                             Laminin                                    P        Dot, IF, IHC-F, IHC-P                   Rb        Ma, Am, Av, Re                     ab11575
                             Laminin [A5]                               M        ICC, IHC-Fr, WB                         Rt        Hu, Mm, Ba                          ab2500
                             Laminin [LAM-89]                           M        IF, IHC-P                               Mm        Hu, F, Rb.
                                                                                                                                   Does not react with Mm, Rt, Ch, D,
                                                                                                                                   Gp, Li, Pi, Sh or Sn               ab11574
Cell adhesion proteins




                             Laminin [MEC5]                             M        IHC-Fr                                  Rt        Hu, Mm, Rt                          ab2466
                             Laminin 2 alpha [4H8-2]                    M        ELISA, ICC, IF, IP, WB                  Rt        Hu, Mm                             ab11576
                             Laminin 5                                  P        IHC-Fr, WB                              Rb        Hu                                 ab14509
                             Laminin B2 gamma 1 [SPM277]                M        IF, IHC-P, IP, WB                       Rt        Hu, Mm                             ab17792
                             Laminin S [C4]                             M        IP, WB                                  Mm        Hu, Rt, B, Pi, Gp, Ch               ab3289
                             67kDa Laminin Receptor                     P        ICC, IF, IHC-P, IP, WB                  Rb        Hu, Mm                               ab711
                             67kDa Laminin Receptor [MLuC5]             M        FACS, ICC, IF, IHC-P                    Mm        Hu, Rt                              ab3099
                             Nestin                                     P        ICC, IF                                 Rb        Hu, Ha, Mk
                                                                                                                                   Does not react with Mm              ab5968
                             Nestin [10C2]                              M        IF, IHC-Fr, IHC-P, WB                   Mm        Hu.
                                                                                                                                   Does not react with rodent nestin ab22035
                             Nestin [2C13A11]                           M        FACS, ICC, IP, WB                       Mm        Hu.
                                                                                                                                   Does not react with Rt             ab18102
                             Nestin [2Q178]                             M        EM, ICC, IHC-Fr, IHC-P, WB              Mm        Mm, Rt
                                                                                                                                   Does not react with Hu, F, Mk or Sh ab6142
                             Nestin [3k1]                               M        ELISA, FACS, ICC,
                                                                                 IHC (aldehyde-based fixation), IP, WB   Mm        Hu                                 ab6320
                             68kDa Neurofilament [1D2]                  M        ICC, IF, IHC-Fr, IHC-P, WB              Mm        Hu,   Rt                           ab4571
                             68kDa Neurofilament [NR4]                  M        IF                                      Mm        Hu,   Rt, Ch, Pi                  ab11219
                             68kDa Neurofilament [SPM204]               M        IHC-P, WB                               Mm        Hu                                ab17832
                             70 kDa Neurofilament Light                 P        IHC-F, IHC-Fr, IHC-P, WB                Rb        Hu,   Mm, Rt, B, Pi, Av            ab9035
                             70 kDa Neurofilament Light [2F11]          M        IHC-Fr, IHC-P, WB                       Mm        Hu,   Op                           ab8970
                             70 kDa Neurofilament Light [DA2]           M        ICC, IF, IHC-Fr, WB                     Mm        Hu,   Mm, Rt, Ch, C, Pi            ab4572
                             160 kDa Neurofilament Medium               P        IF, IHC-F, IHC-Fr, IHC-P, WB            Rb        Hu,   Mm, Rt, F, B, Pi, Re, Av     ab9034
                             160 kDa Neurofilament Medium [3H11]        M        IHC-F, IHC-Fr, IHC-P, WB                Mm        Hu                                 ab7256
                             160 kDa Neurofilament Medium [RNF403]      M        IHC-Fr, WB                              Mm        Hu,   Rt                           ab9271



                                 160 kD Neurofilament Medium antibody [NF-09] (ab7794)

                                                         IF - ab7794 at a dilution of 1/1000, staining on rat brain tissue (30µm thick coronal sections) in free floating IHC.


                                                         Clonality    Applications tested               Host             Species reactivity                Datasheet
                                                            M         WB, ELISA, IHC-P, IHC-Fr, IF, ICC Mm               Ma                                www.abcam.com/ab7794




                                                                      Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                         6                                                                    Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments

Target                                      Clonality   Applications tested                  Host       Species reactivity                Datasheet
                                                                                                                                          www.abcam.com/...

200 kDa Neurofilament Heavy                    P        IF, IHC-Fr, IHC-P, WB                 Rb        F, B, Hu, Mm, Pi, Rt                ab8135
200 kDa Neurofilament Heavy [NAP4]             M        ELISA, IHC-F, IHC-Fr, IHC-P, WB       Mm        Av, Ma                              ab7257
200 kDa Neurofilament Heavy [RNF402]           M        IHC-Fr, IHC-P, WB                     Mm        Hu, Rb, Rt, Mm, B, D, Sh,
                                                                                                        Gp, Ch, Ha, Mk, X                   ab3966
200 kDa Neurofilament Heavy [SPM203]           M        IHC-P, WB                             Mm        Hu                                 ab17879
200kDa + 70kDa Neurofilament [2F11]            M        IF, IHC, IHC-P, IP, WB                Mm        Hu                                 ab17114
Peripherin                                     P        ELISA, ICC, IF, IHC-F, IHC-P, WB      Rb        Ma                                  ab7258
Peripherin [2Q135]                             M        ICC, WB                               Mm        Hu, Mm, Rt, C, Pi.
                                                                                                        Does not react with Ch             ab17999
Peripherin   [7C5]                             M        ICC, IHC-P, WB                        Mm        Ch                                  ab4573
Peripherin   [8G2]                             M        ELISA, ICC, IHC-F, IHC-P, WB          Mm        Ma                                  ab7657
Peripherin   variant PER56                     P        IHC-Fr, IHC-P, WB                     Rb        Hu, Mm                              ab4655
Peripherin   variant PER61                     P        IHC-Fr, IHC-P, WB                     Rb        Hu, Mm                              ab4646



    200 kD Neurofilament Heavy antibody [NF-01] (ab7795)

                                IF - ab7795 at a dilution of 1/1000, staining in rat brain tissue (30 µm thick coronal sections) on free floating IHC.


                                Clonality    Applications tested               Host          Species reactivity                 Datasheet
                                   M         WB, ELISA, IHC-P, IHC-Fr, IF, ICC Mm            Ma                                 www.abcam.com/ab7795




                                                                                                                                                                     Cell adhesion proteins
Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Microtubules

Target                                      Clonality   Applications tested                  Host       Species reactivity              Datasheet
                                                                                                                                       www.abcam.com/...

beta III Tubulin [TU-20]                       M        ICC, IF, IHC-P, IP, WB                Mm        Ma                                  ab7751
beta III Tubulin [TUJ-1]                       M        ICC, IF, IHC-Fr, WB                   Mm        Hu, Rt                             ab14545
Doublecortin                                   P        IHC-Fr                                Gp        Hu, Mm, Rt                         ab10293
MAP2                                           P        IF, IHC, WB                           Ch        B, Hu, Mm, Rt                       ab5392
MAP2 [AP-20]                                   M        ICC, WB                               Mm        Mm, Rt, X, B, Q, S                 ab11268
MAP2 [HM-2]                                    M        ICC, IHC, WB                          Mm        Hu, Mm, Rt, B, Ch, Q               ab11267
MAP2 [MT-01]                                   M        ICC, IF, IP, WB                       Mm        Mm, F, C, Pi                        ab7756
MAP2a + MAP2b [AP20]                           M        ICC, IF, IHC-P, WB                    Mm        Hu, Rt, Mm, B, Ch, X , Q            ab3096
MAP2a + MAP2b [MT-01]                          M        ELISA, IHC-Fr, IHC-P, WB              Mm        Hu, Mm, F                           ab8479
MAP5 [3G5]                                     M        IF, IHC-P, IHC on primary cultures    Mm        Hu, Mm, Rt, C.
                                                                                                        Does not react with Ch              ab3095



Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Regulation

Target                                      Clonality   Applications tested                  Host       Species reactivity               Datasheet
                                                                                                                                         www.abcam.com/...

Thrombospondin 1 [CSI 002-65]                  M        ELISA, IHC, IHC-Fr, IP                Mm        Hu, B                              ab23420



Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Thin Filaments

Target                                      Clonality   Applications tested                  Host       Species reactivity               Datasheet
                                                                                                                                         www.abcam.com/...

MYRIP                                          P        Fast track                             Gt       Fast track                         ab10149 Pep. avail.




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Neuroscience > Cell Adhesion Proteins > ECM Proteins

                             Target                                  Clonality   Applications tested              Host      Species reactivity                Datasheet
                                                                                                                                                              www.abcam.com/...

                             Agrin [AGR 131]                            M        ICC, IHC, IRMA, WB                Mm       Mm, Rt                                ab12362
                             Agrin [Agr 247]                            M        ICC, IF                           Mm       Mm, Rt                                ab12364
                             Agrin [Agr 86]                             M        FACS, ICC, WB                     Mm       Mm, Rt                                ab12361
                             Amisyn                                     P        Fast track                        Gt       Fast track                             ab5899 Pep. avail.
                             Bestrophin                                 P        ICC, IHC, IP, WB                  Rb       Hu, Mm, Rt                            ab14927
                             Bestrophin                                 M        WB                                Mm       Hu, Pi, Mk                             ab2182
                             Drebrin                                    P        WB                                Rb       Rt, Hu                                ab11068
                             Drebrin [M2F6]                             M        IHC-Fr, IHC-P, WB                 Mm       Hu, Mm, Rt, Ch, F, Gp, Mk             ab12350
                             Fetuin A                                   P        ELISA, WB                         Rb       Hu                                    ab13980
                             Laminin                                    P        ELISA, IF, IHC-P, RIA             Rb       Hu                                    ab23753
                             Laminin                                    P        ELISA, WB                         Ch       Hu, Mm, Rt                            ab14055
                             Laminin                                    P        Dot, IF, IHC-F, IHC-P             Rb       Ma, Am, Av, Re                        ab11575
                             Laminin [A5]                               M        ICC, IHC-Fr, WB                   Rt       Hu, Mm, Ba                             ab2500
                             Laminin [LAM-89]                           M        IF, IHC-P                         Mm       Hu, F, Rb.
                                                                                                                            Does not react with:
                                                                                                                            Mm, Rt, Ch, D, Gp, Li, Pi, Sh or Sn   ab11574
                             Laminin [MEC5]                             M        IHC-Fr                            Rt       Hu, Mm, Rt                             ab2466
                             Laminin 2 alpha [4H8-2]                    M        ELISA, ICC, IF, IP, WB            Rt       Hu, Mm                                ab11576
                             Laminin 5                                  P        IHC-Fr, WB                        Rb       Hu                                    ab14509
                             Laminin B2 gamma 1 [SPM277]                M        IF, IHC-P, IP, WB                 Rt       Hu, Mm                                ab17792
                             Laminin S [C4]                             M        IP, WB                            Mm       Hu, Rt, B, Pi, Gp, Ch                  ab3289
                             67kDa Laminin Receptor                     P        ICC, IF, IHC-P, IP, WB            Rb       Hu, Mm                                  ab711
Cell adhesion proteins




                             67kDa Laminin Receptor [MLuC5]             M        FACS, ICC, IF, IHC-P              Mm       Hu, Rt                                 ab3099
                             Mint3                                      P        WB                                Rb       Rt, Mm                                 ab3450 Pep. avail.
                             NCAM [123C3]                               M        IF, IHC-F, IHC-Fr, IHC-P          Mm       Rt, Hu                                 ab8077
                             NCAM [B332 (123A8)]                        M        FACS, IHC-Fr, WB                  Mm       Hu                                     ab8596
                             NCAM [ERIC-1]                              M        ELISA, IHC-Fr, IP, RIA, WB        Mm       Hu                                     ab6123
                             NCAM [H28-123]                             M        AP, IHC-Fr, IM, WB                Rt       Mm                                    ab19782
                             NCAM [MEM-188]                             M        FACS, IP, WB                      Mm       Hu                                     ab8233
                             NCAM [RNL-1]                               M        ICC, IF, IHC-Fr, WB               Mm       Hu, Mm, Rt                             ab9018
                             Nicastrin                                  P        WB                                Rb       Hu, Mm                                 ab3444 Pep. avail.
                             SIRP [MRC OX-41 ]                          M        FACS, IHC-Fr, IHC-P, WB           Mm       Rt                                     ab9295
                             SIRP alpha                                 P        IHC-P, WB                         Rb       Hu, Mk.
                                                                                                                            Does not react with Mm                 ab2971
                             SIRP alpha                                 P        WB                                Rb       Hu, Rt, Mm                             ab8120 Pep. avail.


                                      67kD Laminin Receptor antibody (ab2508)

                                                         IF - staining observed in the hippocampus in the cytoplasm of some astrocytes and neurons using ab2508.
                                                         Recommended dilution of antibody is 1:300-1:1000 with overnight incubation at room temperature. Free floating IHC
                                                         performed with TSA amplification.


                                                         Clonality    Applications tested                Host     Species reactivity                Datasheet
                                                            P         IHC-Fr, Fl, IP, WB                  Rb      Hu                                www.abcam.com/ab2508




                                          Reelin antibody [142] (ab18569)

                                                         IHC-P - ab18569 detecting Reelin immunoreactivity in Cajal-Retzius cells of the mouse cortex at postnatal day 0.
                                                         ab18569 was used at 1/1000 (overnight incubation at 4°C). Immunoreactivity was visualized using ABC amplification.

                                                         Clonality    Applications tested                Host     Species reactivity                Datasheet
                                                            M         ELISA, ICC, IHC-P, IP              Mm       Many                              www.abcam.com/ab18569




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                         8                                                                    Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Cell Adhesion Proteins > ECM Proteins

Target                              Clonality   Applications tested               Host      Species reactivity            Datasheet
                                                                                                                          www.abcam.com/...

Synaptotagmin                          P        ICC, IP, WB                       Rb        Rt, X                           ab13260
Synaptotagmin                          P        IF, WB                            Rb        Hu, Rt                          ab10104
Synaptotagmin                          P        ELISA, WB                         Ch        Hu, B, Mm, Pi, Rt                ab8037
Synaptotagmin [ASV30]                  M        ICC, IHC, IP, WB                  Mm        Mm, Rt, X, B, Ch, Rb, Sha       ab13259
Synaptotagmin [ASV48]                  M        ICC, IHC, IP, WB                  Mm        Rt, B, Mk, Sha, Mm              ab12255
SynCAM                                 P        WB                                Rb        Rt                               ab3910
Syntrophin [1351]                      M        IF, IP, WB                        Mm        Hu, Mm, Rt, Am, Ch, D, Fi       ab11425
Syntrophin gamma 2                     P        ELISA, WB                         Gt        Hu                              ab15713 Pep. avail.
Tenascin C                             P        WB                                Ch        Hu                              ab16290
Tenascin C [MTn-12]                    M        AF, Dot, ELISA, IF, IHC, IHC-F,
                                                IHC-Fr, IP, WB                     Rt       Mm                               ab6346


            Reelin antibody [G10] (ab18570)

                        IHC-P - ab18570 detecting Reelin immunoreactivity in Cajal-Retzius cells of the mouse cortex at postnatal day 0.
                        ab18569 was used at 1/5000 (overnight incubation at 4°C). Immunoreactivity was visualized using ABC amplification.
                        NB: Antigen retrieval performed (microwave in citrate buffer pH 6).


                        Clonality    Applications tested               Host       Species reactivity               Datasheet
                           M         WB, IP, ELISA, IHC-Fr, ICC, IHC-P Mm         Mm, Rt. Does not react with Hu   www.abcam.com/ab18570




                                                                                                                                                      Cell adhesion proteins
                                            Neuroscience
                                              Abwire at
                                           www.abcam.com/
                                            neuroscience




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Neuroscience > Cell Adhesion Proteins > Membrane Proteins

                              Target                                       Clonality   Applications tested               Host      Species reactivity            Datasheet
                                                                                                                                                                 www.abcam.com/...

                              Cathepsin B                                 P            ID, WB                            Sh        Hu                                ab211
                              Cathepsin B                                 P            IHC-Fr, IHC-P                     Rb        Hu                               ab7670
                              Cathepsin B [3E1]                           M            IHC-Fr, IHC-P                     Mm        Hu                               ab7430
                              Cathepsin D                                 P            ELISA, WB                         Rb        Hu                              ab19555
                              Cathepsin D                                 P            IHC-Fr, IHC-P                     Rb        Hu                                ab826
                              Cathepsin D [CTD-19]                        M            ELISA, IHC-F, IHC-P, WB           Mm        Hu                               ab6313
                              Cathepsin D [D101]                          M            IHC-Fr, IHC-P                     Mm        Hu                               ab7433
                              Cathepsin G                                 P            ELISA, WB                         Rb        Hu                              ab20725
                              Cathepsin G                                 P            IHC-Fr, IHC-P                     Rb        Hu                              ab15988
                              Cathepsin G                                 P            WB                                Sh        Hu                               ab8816
                              Cathepsin H [1D10]                          M            IHC-Fr, IHC-P, WB                 Mm        Hu                               ab7432
                              Cathepsin L                                 P            IHC-Fr, IHC-P                     Sh        Hu                               ab7454
                              Cathepsin L [33/2]                          M            ELISA, IHC-Fr, WB                 Mm        Hu, Mm, Rt, Mi                   ab6314
                              Heparan Sulfate Proteoglycan 2 [CSI 001-74] M            AP, ELISA, IHC, IHC-Fr, IP, WB    Mm        Hu, C                           ab23418
                              Heparan Sulfate Proteoglycan 2
                              [SPM255], prediluted                        M            IHC-P                             Rt        Hu,   Mm, B, Pi                 ab17848
                              MOSP [CE1]                                  M            IF, IHC-Fr                        Mm        Hu,   Rt, Mm, F, Ch, Mk, Ca      ab3094
                              Myelin Basic Protein                        P            WB                                Rb        Hu,   Mm, Rt                    ab12355
                              Myelin Basic Protein                        P            IF, IHC-Fr, IHC-P                 Rb        Hu,   Rt                         ab2404
                              Myelin Basic Protein [2B5]                  M            ICC, IHC-F, IHC-Fr, IHC-P         Mm        Hu                               ab8053
                              Myelin Basic Protein [12]                   M            AF, ELISA, IF, IHC-Fr, PCC,
                                                                                       RIA, WB                           Rt        Hu, B, Gp, Mm, Rb, Rt, Sh        ab7349
Cell adhesion proteins




                              Myelin Basic Protein [26]                       M        IHC-Fr                            Mm        MBP from most species           ab11162
                              Myelin Basic Protein [B505]                     M        IHC-Fr, IHC-P                     Mm        Hu, Rb, Rt, C, Mk                ab8764
                              Myelin Basic Protein [Clone 2]                  M        ELISA, IHC-Fr                     Mm        Hu, Rt, B, Gp, Rb, Sh           ab11159
                              Myelin PLP [plpc 1]                             M        IF, IHC-Fr, WB                    Mm        Ma                               ab9311
                              PMP22                                           P        IHC-P                             Rb        Hu                              ab15506
                              PMP22, prediluted                               P        IHC-P                             Rb        Hu                              ab15507
                              PMP22 [20-14]                                   M        IHC-P                             Mm        Hu                               ab3278
                              SORL1                                           P        Fast track                        Gt        Fast track                      ab22814
                              Spinesin                                        P        WB                                Gt        Mm                               ab2245

                              Proteins
                              Myelin Basic Protein protein (Biotin)                                                                                                   ab792


                                                 NrCAM antibody (ab24344)

                                                               IF - ab24344 (1/300) detects NrCAM on embryonic day 11.5 mouse spinal cord. Floor plate commissurral axons
                                                               crossing to the contralateral side of the spinal cord are shown here labeled for NrCAM. Mouse spinal cord was 4%
                                                               PFA-fixed and processed on slide for IF.




                                                               Clonality    Applications tested                  Host    Species reactivity              Datasheet
                                                                  P         IF, IHC-F, IHC-P, IHC-FrFl, IP, WB    Rb     Hu, Mm, Rt                      www.abcam.com/ab24344




                              Neuroscience > Cell Adhesion Proteins > Nuclear Proteins

                              Target                                       Clonality   Applications tested               Host      Species reactivity            Datasheet
                                                                                                                                                                 www.abcam.com/...

                              Galectin 3                                      P        IHC, WB                           Rb        Hu                               ab2473
                              Galectin 3 [A3A12]                              M        ELISA, FACS, IF, IHC-Fr, IP, WB   Mm        Hu, Rt, Mm                       ab2785
                              Galectin 7                                      P        IP, WB                            Rb        Mm                              ab10482




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                         10                                                                         Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Growth and Development > Axonal Guidance Proteins

Target                          Clonality   Applications tested                 Host   Species reactivity        Datasheet
                                                                                                                 www.abcam.com/...

Aggrecan ARGxx [BC-3]              M        ELISA, IHC-Fr, IHC-P, WB            Mm     Hu, B, F, D, Gp, H, Pi,
                                                                                       Rb, Rt, Sh                  ab3773
AMIGO2                             P        WB                                  Rb     Mm, Rt                     ab16762
CRMP5 [CR-1]                       M        IHC-Fr, WB                          Rt     Hu, Rt, B                  ab19378
CRMP5 [CR-3]                       M        IHC-Fr, WB                          Rt     Hu, Mm, Rt, B              ab19352
EphA1                              P        ELISA, WB                           Rb     Hu                          ab5385
EphA1                              P        I-ELISA, WB                         Gt     Hu                          ab7036
EphA2                              P        ELISA, WB                           Rb     Ha, Hu, Mm                  ab5387
EphA2                              P        BL, ELISA, ICC, IHC-Fr, WB          Gt     Mm                         ab10610
EphA3                              P        I-ELISA, WB                         Gt     Mm                          ab7038
EphA3                              P        ELISA, WB                           Gt     Hu.
                                                                                       Does not react with Mm     ab10611
EphA3 [III-A4]                     M        FACS, IP                            Mm     Hu                         ab19439
EphA4                              P        ELISA, WB                           Rb     Hu                          ab5389
EphA4                              P        I-ELISA, WB                         Gt     Mm                          ab7039
EphA4                              P        I-ELISA, WB                         Gt     Hu                          ab7041
EphA5                              P        ELISA, WB                           Rb     Hu, Mm                      ab5397
EphA5                              P        ELISA, WB                           Gt     Mm, Rt                     ab10612
EphA6                              P        ELISA, WB                           Gt     Mm                         ab10613
EphA7                              P        ELISA, WB                           Rb     Hu                          ab5411
EphA7                              P        ELISA, WB                           Gt     Mm                         ab10614




                                                                                                                                          Growth and development
EphA8                              P        ELISA, WB                           Gt     Mm                         ab10615
EphB1                              P        ELISA, WB                           Rb     Hu, Mm                      ab5414
EphB1                              P        I-ELISA, WB                         Gt     Rt                          ab7042
EphB1                              P        Dot, IP                             Sh     Hu                         ab10406
EphB2                              P        ELISA, WB                           Rb     Hu, Mm                      ab5418
EphB2                              P        Dot, ELISA                          Gt     Mm                         ab10616
EphB3                              P        ELISA, WB                           Gt     Mm                         ab10617
EphB3                              P        ELISA, WB                           Gt     Hu                          ab7044
EphB4                              P        Dot, ELISA, Inhib                   Gt     Mm                         ab10618
EphB6                              P        Dot, ELISA                          Gt     Mm                         ab10619
L1CAM [UJ127]                      M        IF, IHC-P, IP, WB                   Mm     Hu                          ab3200
L1CAM [UJ12711]                    M        IP, WB                              Mm     Hu                         ab20148
L1CAM [UJ1814]                     M        IP, WB                              Mm     Hu                         ab20149
Neuropilin 1                       P        ELISA, WB                           Gt     Hu                         ab18130
Neuropilin 1                       P        IHC-P, WB                           Rb     Rt, Mm                     ab16786
Neuroserpin                        P        IHC, WB                             Rb     Hu                         ab16171
NRG1                               P        WB                                  Rb     Hu, Mm                      ab2994
NRG1 [7D5]                         M        IHC-Fr, IHC-P, IP, WB               Mm     Rt, Mm                      ab2369
NRP2                               P        WB                                  Ch     Hu                         ab15874
Reelin [142]                       M        ELISA, ICC, IHC-P, IP, WB           Mm     Ma, Av                     ab18569
Reelin [G10]                       M        ELISA, ICC, IHC-Fr, IHC-P, IP, WB   Mm     Mm, Rt.
                                                                                       Does not react with Hu     ab18570
Robo1                              P        ELISA, IF, WB                       Rb     Mm                          ab7279
Robo4                              P        WB                                  Rb     Mm                         ab10547
Slit1                              P        WB                                  Rb     Mm, Rt                     ab10984
Slit2                              P        Fast track                          Rb     Fast track                  ab7665

Proteins
Robo4 protein                                                                                                     ab19112




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Neuroscience > Growth and Development > Neurogenesis

                              Target                                     Clonality   Applications tested                Host       Species reactivity          Datasheet
                                                                                                                                                               www.abcam.com/...

                              Axotrophin                                    P        WB                                  Ch        Hu, Mm, Rt                   ab13997
                              Cdk5                                          P        ELISA, WB                           Rb        Hu, Mm, Rt                   ab19426
                              Cdk5 [SPM236], prediluted                     M        IHC-P                               Mm        Hu, Mm, Rt                   ab17875
                              DYRK1A                                        P        IF, IP, WB                          Sh        Hu                           ab16140
                              PTPR                                          P        WB                                  Rb        Hu                           ab12153
                              STMN2                                         P        Fast track                          Gt        Fast track                   ab21190


                                               FOX1A antibody (ab12161)

                                                             ICC - ab12161 staining (1/200) in mouse E11 cortical cells cultured for 6 days.


                                                             Clonality    Applications tested                Host       Species reactivity              Datasheet
                                                                P         WB, IF, ICC, IHC                    Rb        Hu, Mm                          www.abcam.com/ab12161




                              Neuroscience > Growth & Development > Neurotrophins
Growth and development




                              Target                                     Clonality   Applications tested                Host       Species reactivity          Datasheet
                                                                                                                                                               www.abcam.com/...

                              Artemin                                       P        WB                                  Rb        Hu                            ab1136
                              BDNF                                          P        ELISA, WB                           Rb        Hu                            ab9793
                              BDNF [35928.11]                               M        ELISA, WB                           Mm        Hu                           ab10505
                              BDNF (Biotin)                                 P        ELISA, WB                           Rb        Hu                           ab12385
                              BMP2                                          P        Dot, ELISA, WB                      Rb        Hu, Mm, Rt                   ab14933
                              BMP2                                          P        ELISA, WB                           Rb        Hu                           ab17885
                              BMP2 [65529.111]                              M        I-ELISA, WB                         Mm        Hu                            ab6285
                              BMP2 (Biotin)                                 P        ELISA, WB                           Rb        Hu                           ab17597
                              CNTF                                          P        I-ELISA, Neut, WB                   Gt        Rt                           ab10834
                              CNTF                                          P        ELISA, Neut, WB                     Rb        Rt                            ab9785
                              CNTF                                          P        ELISA, IHC, WB                      Ch        Hu, Mm, Rt                   ab17692
                              CNTF [AS23]                                   M        ELISA, IP, WB                       Mm        Hu                           ab17284
                              CNTF (Biotin)                                 P        ELISA, WB                           Rb        Rt                           ab12426
                              GDNF                                          P        I-ELISA, Neut, WB                   Gt        Hu                           ab10835
                              GDNF                                          P        Dot, IHC-Fr, WB                     Sh        Hu                            ab6206
                              GDNF                                          P        ELISA, IHC, WB                      Ch        Hu, Mm, Rt                   ab17637
                              GDNF family Receptor alpha 2                  P        IHC-Fr, WB                          Rb        Mm, Rt                        ab6170
                              GDNF family Receptor alpha 3                  P        IHC-Fr, WB                          Rb        Mm, Rt                        ab6171
                              GDNF family Receptor alpha 3                  P        WB                                  Rb        Hu, Rt, Mm                    ab8028 Pep. avail.
                              GDNFR alpha                                   P        WB                                  Rb        Hu, Rt, Mm                    ab8026 Pep. avail.
                              GFR alpha 2                                   P        WB                                  Rb        Hu, Mm, Rt                   ab19146



                                                 BDNF antibody (ab6201)

                                                             IHC - immunostaining BDNF-containing hippocampal neurons in coronal rat brain sections (30 microns). ab6201 used
                                                             at 1/100 dilution.

                                                             Clonality    Applications tested                Host       Species reactivity              Datasheet
                                                                P         Dot, ELISA, IHC-Fr, Neut, WB        Rb        Hu, Rt                          www.abcam.com/ab6201




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                         12                                                                       Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Growth & Development > Neurotrophins

Target                                  Clonality   Applications tested                  Host        Species reactivity                 Datasheet
                                                                                                                                        www.abcam.com/...

GFR alpha 3                                P        WB                                   Rb          Hu, Mm, Rt                          ab19135
LANGF Receptor [MC-192]                    M        FACS, IHC-Fr                        Mm           Rt                                   ab6172
Neurotrophin 3                             P        Dot, ELISA, IHC-Fr, Neut, WB         Rb          Hu                                   ab6202
Neurotrophin 3                             P        ELISA, IHC-Fr, IHC-P, WB             Gt          Hu, Rt                              ab10334
Neurotrophin 3 (Biotin)                    P        ELISA, WB                            Gt          Hu                                  ab17524
Neurotrophin 4                             P        ELISA, Neut, WB                      Gt          Hu                                   ab9824
Neurotrophin 4                             M        ELISA                               Mm           Hu                                   ab9330
Neurotrophin 4 (Biotin)                    P        ELISA, WB                            Rb          Hu                                  ab17888
Neurotrophin 4/5                           P        Dot, ELISA, IHC-Fr, Neut, WB         Rb          Hu                                   ab6205
Neurturin                                  P        Dot, ELISA, IHC-Fr, WB               Sh          Hu                                   ab6208
Neurturin                                  P        WB                                   Rb          Hu                                   ab8061
Neurturin peptide                                   BL                                                                                    ab8393
NGF                                        P        Inhib, Dot, ELISA, IHC-Fr, Neut, WB Rb           Mm                                   ab6198
NGF [1.A.15]                               M        ELISA                               Mm           Hu                                  ab18167
NGF 2.5S                                   P        Dot, Inhib, WB                       Rb          Hu, Mm, Ch                          ab10515
NGF beta                                   P        ELISA, Neut, WB                      Gt          Hu, Mm, Rt                          ab10837
NGF beta [25623.1]                         M        Dot, ELISA, Inhib                   Mm                                               ab10513
NRG1                                       P        WB                                   Rb          Hu, Mm                               ab2994
NRG1 [7D5]                                 M        IHC-Fr, IHC-P, IP, WB               Mm           Rt, Mm                               ab2369
p75 NGF Receptor                           P        Dot, FACS, IF, IHC-Fr, IHC-P, IP, WB Rb          Mm, Rt                               ab8874
p75 NGF Receptor [12A8]                    M        Dot, ICC, IHC-Fr, IP, WB             Rt          Mm                                   ab8876




                                                                                                                                                                 Growth and development
p75 NGF Receptor [ME20.4]                  M        EM, ELISA, FACS, ICC, IF,           Mm           Hu, F, Pi .
                                                    IHC-P, Inhib, IP, RIA, WB                        Does not react with Mm, Rt or Ch    ab10495
p75 NGF Receptor [NGFR5]                   M        FACS, IF, IHC-P                     Mm           Hu, Ba, F, Ca, Mk, Rb
                                                                                                     Does not react with Mm or Rt         ab3125
Pleiotrophin                               P        ELISA, WB                             Rb         Hu                                  ab14025
Pleiotrophin                               P        ELISA, WB                             Gt         Hu                                  ab10849
SPON1                                      P        WB                                    Ch         Hu, Mm, Rt, C                       ab14271
TrkA (phospho Y490)                        P        ICC, IP, WB                           Rb         Hu, Mm, Rt                           ab1445
TrkA/B [1.A.37]                            M        IP, WB                                Mm         Hu                                  ab18137
TrkB                                       P        IHC-Fr                                Rb         Rt                                   ab6180
TrkB                                       P        I-ELISA, WB                           Gt         Hu                                  ab10841

Proteins
BDNF protein                                                                                                                              ab9794
CNTF protein                                                                                                                              ab9786
GDNF protein                                                                                                                              ab9790
Neurotrophin 3 protein                                                                                                                    ab9792
Neurotrophin 4 protein                                                                                                                    ab9825
Neurturin protein                                                                                                                         ab9840
NGF beta protein                                                                                                                          ab9796


                      TrkA antibody (ab8871)

                            IF - ab8871 immunostaining in terminals of primary afferent fibers (fibers in the top part of the figure) of the dorsal root
                            ganglion. Free floating IHC performed on 30um cryostat sections. Primary antibody ab8871 was used at 1/3000 and
                            incubated overnight at room temperature.


                            Clonality    Applications tested                  Host        Species reactivity                Datasheet
                               P         IHC-Fr, IHC-FrFl, IF                  Rb         Rt                                www.abcam.com/ab8871




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Neuroscience > Growth and Development > Notch Pathway

                              Target                                   Clonality   Applications tested        Host   Species reactivity                 Datasheet
                                                                                                                                                        www.abcam.com/...

                              ADAM10                                      P        WB                         Rb     Hu                                  ab10956
                              APH1a                                       P        WB                         Rb     Rt, Hu, Mm                          ab12104   Pep. avail.
                              APH1a                                       P        IF, IP, WB                 Rb     Hu, Mm                              ab19390
                              DLL4                                        P        ELISA, IHC-F, IHC-P, WB    Rb     Hu, Mm                               ab7280
                              Jagged 1                                    P        ELISA, FACS, Neut, WB      Gt     Hu, Rt                              ab10580
                              Jagged 2                                    P        Fast track                 Rb     Fast track                          ab10556
                              LNX                                         P        Fast track                 Gt     Fast track                           ab4538
                              MAML1                                       P        Fast track                 Gt     Fast track                          ab17019   Pep. avail.
                              Notch1 [A6]                                 M        FACS, IHC-P, WB            Mm     Hu, Mm                               ab3294
                              Notch1 (activated)                          P        Co-IP, ICC, IF, IP, WB     Rb     Hu, Mm                               ab8925   Pep. avail.
                              Notch2 (activated)                          P        Fast track                 Rb     Fast track                           ab8926   Pep. avail.
                              Notch1 intra                                P        WB                         Rb     Hu.
                                                                                                                     Does not react with Mm               ab8387   Pep. avail.
                              Notch1 [SPM206], prediluted                 M        IHC-P                      Mm     Hu, Mm                              ab17843
                              Notch1 intra + Notch2 intra                 P        Fast track                 Rb     Fast track                           ab8928   Pep. avail.
                              Notch 2 intra                               P        WB                         Rb     Hu                                   ab8927   Pep. avail.
                              NUMB                                        P        IF, IHC-P, IM, WB          Gt     Hu, Mm                               ab4147   Pep. avail.
                              NUMB                                        P        IP, WB                     Rb     Hu, Mm                              ab14140   Pep. avail.
                              NUMBL                                       P        Fast track                 Gt     Fast track                           ab5641   Pep. avail.
                              PEN2                                        P        IP, WB                     Rb     Hu                                  ab16555
                              Presenilin 1                                P        ELISA, IHC-Fr, IHC-P, WB   Gt     Hu                                   ab7297
Growth and development




                              Presenilin 1, prediluted                    P        IHC-P                      Rb     Hu                                  ab15508
                              Presenilin 1 [APS 11]                       M        ELISA, IF, IHC-P, WB       Mm     Hu, Mm, Rt                          ab15456
                              Presenilin 1 [APS 18]                       M        ELISA, IF, WB              Mm     Hu, Mm, Rt                          ab15458
                              Presenilin 2                                P        ELISA, IHC-Fr, IHC-P       Gt     Hu                                  ab11148
                              Presenilin 2                                P        ELISA, IHC, WB             Ch     Hu, Mm, Rt                          ab18041
                              Presenilin 2 [198C67921]                    M        WB                         Mm     Hu                                  ab13926
                              Presenilin 2 [APS 26]                       M        ELISA, IF, WB              Mm     Hu, Mm                              ab15549
                              SIAH Interacting Protein                    P        Fast track                 Gt     Fast track                           ab4276   Pep. avail.
                              SIAH1                                       P        WB                         Gt     Hu                                   ab2237   Pep. avail.



                              Neuroscience > Growth and Development > Signal Transduction

                              Target                                   Clonality   Applications tested        Host   Species reactivity                 Datasheet
                                                                                                                                                        www.abcam.com/...

                              14-3-3                                      P        IP, WB                     Rb     Hu, Mm, Rt                           ab9063
                              14-3-3                                      P        IHC-P, IP, WB              Rb     Hu, Mm, Rt                           ab6081
                              14-3-3 [2Q248]                              M        WB                         Mm     Rt                                  ab14121
                              14-3-3 [3F7]                                M        IP, WB                     Mm     Hu                                  ab14108
                              14-3-3 beta                                 P        IHC-P, IP, WB              Rb     Hu, Mm, Rt                          ab15260
                              14-3-3 beta                                 P        WB                         Rb     Hu, Mm, Rt                          ab16730
                              14-3-3 beta [60C10]                         M        ELISA, WB                  Mm     Hu, Mm, Rt                          ab16859
                              14-3-3 beta, prediluted                     P        IHC-P                      Rb     Hu, Mm, Rt                          ab15262
                              14-3-3 beta + epsilon + zeta [3C8]          M        WB                         Mm     Hu, Mm, Rt                          ab12346
                              14-3-3 beta + zeta                          P        WB                         Rb     Ma, Dm                              ab14113
                              14-3-3 beta + zeta [22-IID8B]               M        ICC, IHC, WB               Mm     Hu, Mm, Rt, B, D, Mk, Pi, Rb, Sh    ab12347
                              14-3-3 eta + gamma + zeta                   P        ELISA, WB                  Rb     Many                                ab14124
                              14-3-3 gamma (acetyl V1) [KC21]             M        WB                         Mm     Hu                                  ab17005
                              14-3-3 gamma [3F8]                          M        IP, WB                     Mm     Hu                                  ab14117
                              14-3-3 sigma [1N6]                          M        IF, IHC-P, IP, WB          Mm     Hu                                  ab14123
                              14-3-3 tau [3B9]                            M        IP, WB                     Mm     Hu, Mm, Rt, B                       ab10439
                              14-3-3 Binding Motif (phospho S)            P        ELISA, IHC-P, IP, WB       Rb     Many                                ab14127
                              14-3-3 Binding Motif (phospho S) [3i2]      M        ELISA, IP, WB              Mm     Many                                ab14126
                              Agrin [AGR 131]                             M        ICC, IHC, IRMA, WB         Mm     Mm, Rt                              ab12362
                              Agrin [Agr 247]                             M        ICC, IF                    Mm     Mm, Rt                              ab12364
                              Agrin [Agr 86]                              M        FACS, ICC, WB              Mm     Mm, Rt                              ab12361
                              AKT                                         P        WB                         Ch     Hu, Mm, Rt, X , B                   ab13990
                              AKT                                         P        ICC, IP, WB                Rb     Hu, Mm, Rt                           ab6076




                                                                        Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                         14                                                                     Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Growth and Development > Signal Transduction

Target                                   Clonality   Applications tested                Host      Species reactivity              Datasheet
                                                                                                                                  www.abcam.com/...

AKT (unmodified S473) [BDI111]              M        ELISA, WB                          Mm        Hu                                ab19442
AKT (phospho S473)                          P        IF                                 Rb        Hu, Mm                            ab20488
AKT (phospho T308)                          P        IF, WB                             Rb        Hu                                 ab8933
AKT (phospho T34)                           P        ELISA, WB                          Rb        Hu, Mm, Rt, Rb                    ab23509
AKT peptide                                          BL                                                                              ab9041
CrkL                                        P        WB                                 Gt        Hu,   Mm                          ab10907
CSN7b                                       P        WB                                 Rb        Hu                                ab11895
Ctip1 [14B5]                                M        ICC, IF, IHC, IP, WB               Mm        Hu,   Mm, Fi                      ab19487
Ctip1 [15E3AC11]                            M        ICC, IF, IHC, IP, WB               Mm        Hu,   Mm                          ab18688
Ctip1 [18B12DE6]                            M        ICC, IF, IHC, IP, WB               Mm        Hu,   Mm                          ab19489



                   AKT antibody (ab8805)

                             IF - ab8805 used at 1/80 on cultured neonatal rat cardiomyocytes that express a nuclear-targeted AKT construct. AKT
                             staining (green) and actin filaments (red).


                             Clonality    Applications tested                Host       Species reactivity               Datasheet
                                P         WB, IHC-P, IF, ICC, IP,             Rb        Hu                               www.abcam.com/ab8805
                                          Transfected Cell Culture, PCC




                                                                                                                                                           Growth and development
         AKT (phospho S473) antibody (ab8932)

                             IF - AKT is phosphorylated on Ser 473 in breast tumor. The staining is much stronger than the weak basal level of
                             phosphorylation in normal breast. The staining is cytoplasmic, as in normal tissue. The phospho Ser 473 AKT
                             antibody (ab8932) is used with no pretreatment at a dilution of 1:100.


                             Clonality    Applications tested                Host       Species reactivity               Datasheet
                                P         WB, IHC-P, IF                       Rb        Hu                               www.abcam.com/ab8932




         AKT (phospho S473) antibody (ab4802)

                             IF - detection of AKT phospho S473 at a dilution of 1/200 (24h incubation at RT). Perinuclear staining observed in
                             ventral horn neurons of rat spinal cord (30µm saggital sections).

                             Clonality    Applications tested                Host       Species reactivity               Datasheet
                                P         WB, IHC-P, IHC-Fr, IF, ICC, IHC     Rb        Hu, Mm, Rt                       www.abcam.com/ab4802




         AKT (phospho T308) antibody (ab4796)

                             IHC - ab4796 at a dilution of 1/100 (2 overnight incubations at room temperature; ABC amplification). Cytoplasmic and
                             nuclear staining observed in rat spinal cord motorneurons (ventral horn) 30µm saggital spinal cord sections.



                             Clonality    Applications tested                Host       Species reactivity               Datasheet
                                P         WB, IHC                             Rb        Hu, Mm, Rt                       www.abcam.com/ab4796




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Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM)                                                                   15
Neuroscience > Growth and Development > Signal Transduction

                              Target                              Clonality    Applications tested                 Host     Species reactivity             Datasheet
                                                                                                                                                           www.abcam.com/...

                              Dab1                                     P       IP, WB                              Gt       Mm                              ab16674
                              Dab1                                     P       IF, IHC-Fr, IP, WB                  Rb       Mm                               ab7522
                              Dab1 (phospho S491)                      P       WB                                  Rb       Hu                               ab5776
                              Dab1 (phospho Y198)                      P       WB                                  Rb       Hu                               ab5673
                              Dab1 (phospho Y220)                      P       WB                                  Rb       Hu                               ab5677
                              Dispatched                               P       Fast track                          Gt       Fast track                      ab10142
                              ELAVL2 + ELAVL3 + ELAVL4 [16A11]         M       IHC-Fr, WB                          Mm       Hu, Mm, Rt, Fi                  ab14370
                              EMX2                                     P       IHC, WB                             Rb       Hu, Mm, Rt                      ab11849
                              Fetuin A                                 P       ELISA, WB                           Rb       Hu                              ab13980
                              FMR1 (Drosophila) [6A15]                 M       ELISA, IF, IP, WB                   Mm       Dm.
                                                                                                                            Does not react with Hu          ab10299
                              FOXG1                                    P       WB                                  Gt       Hu                               ab3394   Pep. avail.
                              FOXG1                                    P       IHC-P, WB                           Rb       Hu                              ab23470
                              GCNF                                     P       IHC-P                               Rb       Hu                              ab13007
                              Gemin 1 [2B1]                            M       ELISA, IF, IP, WB                   Mm       Hu, Mm, X                        ab5831
                              Gemin 2 [2E17]                           M       ELISA, IF, IP, WB                   Mm       Hu, X                            ab6084
                              Gemin 3 [12H12]                          M       ELISA, IF, IP, WB                   Mm       Hu                              ab10305
                              Gli1                                     P       IHC-P, IP, WB                       Rb       Hu, Mm                           ab7523
                              Gli2                                     P       Fast track                          Rb       Fast track                       ab7181
                              Gli2                                     P       Fast track                          Rb       Fast track                       ab7195
                              Gli3                                     P       Fast track                          Rb       Fast track                       ab6050
Growth and development




                              LIM Kinase                               P       WB                                  Rb       Mm                              ab10561
                              LIS1                                     P       IP, WB                              Rb       Hu                               ab2607
                              LIS1                                     P       WB                                  Gt       Mm                               ab2656   Pep. avail.
                              MAP4K6                                   P       IHC-P                               Rb       Hu                              ab13140
                              NCAM [123C3]                             M       IF, IHC-F, IHC-Fr, IHC-P            Mm       Rt, Hu                           ab8077
                              NCAM [B332 (123A8)]                      M       FACS, IHC-Fr, WB                    Mm       Hu                               ab8596
                              NCAM [ERIC-1]                            M       ELISA, IHC-Fr, IP, RIA, WB          Mm       Hu                               ab6123
                              NCAM [H28-123]                           M       AP, IHC-Fr, IM, WB                  Rt       Mm                              ab19782
                              NCAM [MEM-188]                           M       FACS, IP, WB                        Mm       Hu                               ab8233
                              NCAM [RNL-1]                             M       ICC, IF, IHC-Fr, WB                 Mm       Hu, Mm, Rt                       ab9018
                              Neuro D4                                 P       Fast track                          Gt       Fast track                       ab3940   Pep. avail.
                              Neuroglobin                              P       ELISA, WB                           Ch       Hu                              ab14010
                              NR2E3                                    P       IHC-P                               Rb       Hu                              ab13081
                              NRG1                                     P       WB                                  Rb       Hu, Mm                           ab2994
                              NRG1 [7D5]                               M       IHC-Fr, IHC-P, IP, WB               Mm       Rt, Mm                           ab2369
                              PAX2                                     P       IHC-P, WB                           Rb       Hu                              ab23799
                              PAX6                                     P       WB                                  Rb       Rt, Sh                           ab5790   Pep. avail.
                              PHOX2A                                   P       IHC, IP, WB                         Rb       Hu, Mm, Rt                      ab12046
                              PHOX2A                                   P       Fast track                          Gt       Fast track                       ab4511
                              PHOX2B                                   P       IHC, IP, WB                         Rb       Rt, Hu, Mm                      ab12047
                              PROX1                                    P       ELISA, IHC-Fr                       Rb       Hu, Mm, Rt, Ch, Fi              ab11941
                              RAI3                                     P       ICC, IHC-P                          Rb       Hu                              ab13274
                              ROR alpha                                P       WB                                  Rb       Hu                              ab16367
                              ROR alpha                                P       IHC-P                               Rb       Hu                              ab13109
                              ROR beta                                 P       IHC-P                               Rb       Hu                              ab13113
                              SCP1                                     P       IF                                  Rb       Hu, Mm                          ab15087
                              SCP1                                     P       IF, IHC-Fr, IHC-P                   Rb       Mm                              ab15090


                                           Ctip2 antibody [25B6] (ab18465)

                                                          IHC - using ab18465 on adult mouse hippocampus.

                                                          Clonality    Applications tested                  Host    Species reactivity               Datasheet
                                                             M         WB, IP, IHC-P, IHC-Fr, IF,            Rt     Hu, Mm, Fi                       www.abcam.com/ab18465
                                                                       ICC, IHC, ChIP




                                                                      Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                         16                                                                   Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Growth and Development > Signal Transduction

Target                          Clonality   Applications tested               Host   Species reactivity       Datasheet
                                                                                                              www.abcam.com/...

SIRP alpha                         P        IHC-P, WB                         Rb     Hu, Mk.
                                                                                     Does not react with Mm     ab2971
SIRP alpha                         P        WB                                Rb     Hu, Rt, Mm                 ab8120 Pep. avail.
SIRP [MRC OX-41 ]                  M        FACS, IHC-Fr, IHC-P, WB           Mm     Rt                         ab9295
Slit1                              P        WB                                Rb     Mm, Rt                    ab10984
Slit2                              P        Fast track                        Rb     Fast track                 ab7665
SOX2                               P        IF                                Rb     Hu, Mm                    ab15830 Pep. avail.
SOX6                               P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12054
SOX8                               P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12055
SOX13                              P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12060
SOX14                              P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12061
SOX22                              P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12062
Sprouty 2                          P        ELISA, IP, WB                     Rb     Hu                         ab1043
SynCAM                             P        WB                                Rb     Rt                         ab3910
Tenascin C                         P        WB                                Ch     Hu                        ab16290
Tenascin C [MTn-12]                M        AF, Dot, ELISA, IF, IHC, IHC-F,
                                            IHC-Fr, IP, WB                    Rt     Mm                         ab6346
TRAF6BP                            P        WB                                Rb     Hu                        ab22049
VCAM1 [14C3]                       M        IF, IHC-P                         Mm     Hu, Mm                    ab11514
VCAM1 [1G11B1]                     M        FACS, IA, ICC, IHC-Fr, IP         Mm     Hu                         ab7219
VCAM1 [M/K-2]                      M        FuncS, IF, IHC                    Rt     Mm                        ab19569




                                                                                                                                          Growth and development
VCAM1 [MVCAMA(429)]                M        FACS                              Rt     Mm                        ab23807
Zic1                               P        IHC, IP, WB                       Rb     Hu, Mm, Rt                ab12070
Zic2                               P        IHC, WB                           Rb     Hu, Mm, Rt                ab12072




                                        Neuroscience
                                          Abwire at
                                       www.abcam.com/
                                        neuroscience




Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM)                                                  17
Neuroscience > Neurodegeneration > Alzheimer’s > Amyloid

                         Target                                     Clonality   Applications tested             Host      Species reactivity            Datasheet
                                                                                                                                                        www.abcam.com/...

                         ADAM10                                         P       WB                               Rb       Hu                               ab10956
                         AMPK alpha 1                                   P       IP, WB                           Rb       B, Hu, Rt                         ab3759
                         Amyloid A Component [mcl], prediluted          M       IHC-Fr, IHC-P                    Mm       Hu                                ab7505
                         Amyloid beta Precursor Protein                 P       ELISA, IHC-Fr, IHC-P, WB         Gt       Hu                               ab17468
                         Amyloid beta Precursor Protein                 P       ICC, IP, WB                      Rb       Hu, Mk                           ab12268
                         Amyloid beta Precursor Protein                 P       ICC, IHC-P, IP, WB               Rb       Hu, Mk                           ab12269
                         Amyloid Precursor Protein                      P       ELISA, IHC-P, WB                 Gt       Hu                               ab17325
                         Amyloid Precursor Protein                      P       IHC-P, IP, WB                    Rb       Hu, Mk                           ab11117
                         Amyloid Precursor Protein                      P       WB                               Rb       Hu, Mm                            ab2073
                         Amyloid Precursor Protein                      P       ELISA, IHC-Fr, IHC-P, WB         Gt       Hu                                ab2084
                         Amyloid Precursor Protein (phospho T668)       P       ICC, IHC-P, IP, WB               Rb       Hu, Mm, Rt                       ab17417
                         Amyloid Precursor Protein [3E9]                M       IHC-P, WB                        Mm       Hu                               ab12338
                         Amyloid Precursor Protein Frameshift Mutant    P       ELISA, IHC-P, WB                 Gt       Hu                                ab2085
                         Amyloid Precursor Protein peptide                      BL                                                                          ab7874
                         APH1a                                          P       IF, IP, WB                       Rb       Hu, Mm                           ab19390
                         APH1a                                          P       WB                               Rb       Rt, Hu, Mm                       ab12104 Pep. avail.
                         beta Amyloid 1-40                              P       ELISA, IHC-Fr, RIA               Rb       Hu                               ab16218
                         beta Amyloid 1-40                              P       IP, WB                           Rb       Hu, Mm                           ab16622
                         beta Amyloid 1-40                              P       ELISA, IHC-P, WB                 Rb       Hu                               ab10147
                         beta Amyloid 1-40 [3H2]                        M       ELISA, IF, IHC-P, WB             Mm       Hu                               ab17331
                         beta Amyloid 1-40 [BAM-10]                     M       IHC-Fr, IHC-P                    Mm       Hu                                ab7501
                         beta Amyloid 1-40 [BDI350]                     M       ELISA, ICC, WB                   Mm       Hu                               ab20068
Neurodegeneration




                         beta Amyloid 1-42                              P       ELISA, IHC-P, WB                 Rb       Hu                               ab10148
                         beta Amyloid 17-42                             P       ELISA                            Rb       Hu                               ab17327
                         beta Amyloid                                   P       ELISA, IHC, WB                   Ch       Hu                               ab17472
                         beta Amyloid                                   P       IHC                              Rb       Ro                               ab14220
                         beta Amyloid                                   P       ELISA, WB                        Rb       Hu, Mm                            ab2539
                         beta Amyloid [2C8]                             M       IHC, WB                          Mm       Hu, Mm                           ab12349
                         beta Amyloid [4G8]                             M       ELISA, IHC-P, IP, WB             Mm       Hu                                ab1910
                         beta Amyloid peptide                                   BL                                                                          ab3698
                         CLACP                                          P       WB                               Rb       Hu, Mm                           ab16763
                         Factor VIII heavy chain [RFFVIIIC/8]           M       ELISA, WB                        Mm       Hu, Pi.
                                                                                                                          Does not react with Mm, Rt or D ab6345


                             Amyloid Precursor Protein antibody [MABDE2B4] (ab12266)

                                                        IHC-P- ab12266 detecting APP in Alzheimer’s disease human brain. Plaques are observed in the neuropil. Amyloid
                                                        deposits stained by DE2B4 (ab12266) can be seen around some blood vessels.



                                                        Clonality    Applications tested               Host     Species reactivity              Datasheet
                                                           M         WB, IP, IHC-P, ICC,               Mm       Hu, C, Mk, Pi                   www.abcam.com/ab12266




                                  beta Amyloid antibody [6E10] (ab10146)

                                                        IHC-P- using ab1910 [clone 4G8] and ab10146 [clone 6E10]. Stains paraffin - embedded cerebellum.


                                                        Clonality    Applications tested               Host     Species reactivity              Datasheet
                                                           M         WB, IP, ELISA, IHC-P              Mm       Hu                              www.abcam.com/ab10146




                                                                       Ordering information: www.abcam.com | Tech support: www.abcam.com/technical
                    18                                                                         Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Neurodegeneration > Alzheimer’s > Amyloid

Target                                  Clonality   Applications tested                 Host      Species reactivity           Datasheet
                                                                                                                               www.abcam.com/...

FE65                                       P        WB                                  Rb        Mm                             ab5668   Pep. avail.
FE65 [4H324]                               M        ICC, IP, WB                         Mm        Hu, Mm, Rt                    ab17469
Humanin                                    P        WB                                  Rb        Hu                            ab16758
Mint1                                      P        WB                                  Rb        Rt                             ab3448   Pep. avail.
Mint3                                      P        WB                                  Rb        Rt, Mm                         ab3450   Pep. avail.
PEN2                                       P        IP, WB                              Rb        Hu                            ab16555
RAGE                                       P        ELISA, IHC-P                        Gt        Hu                            ab20558
RAGE                                       P        IHC-Fr, WB                          Rb        Rt, Mm                         ab3611
SHC                                        P        IP, WB                              Rb        Hu, Mm, Rt                    ab15039
SHC (phospho Y239 + Y240)                  P        WB                                  Rb        Hu                             ab4890   Pep. avail.
SHC (phospho Y317)                         P        WB                                  Rb        Hu, Mm                        ab15040



Neuroscience > Neurodegeneration > Alzheimer’s > Related targets

Target                                  Clonality   Applications tested                 Host      Species reactivity           Datasheet
                                                                                                                               www.abcam.com/...

Acrolein                                   P        ELISA                               Rb        Acrolein                      ab15138
Caspase 6 (active)                         P        WB                                  Rb        Mm, Rt, Hu                     ab2326
ADAM17                                     P        Dot, WB                             Rb        Hu, Rt, Mm                     ab2051   Pep. avail.
ADAM17                                     P        WB                                  Rb        Hu, Rt, Pi                    ab11547




                                                                                                                                                             Neurodegeneration
ADAM17                                     P        WB                                  Gt        Hu                            ab13535   Pep. avail.
Als2                                       P        Fast track                          Gt        Fast track                     ab4155   Pep. avail.
ALS2CR1                                    P        WB                                  Gt        Hu                             ab4123   Pep. avail.
ALS2CR2                                    P        WB                                  Gt        Hu                             ab4122   Pep. avail.
ALS2CR2                                    P        WB                                  Rb        Hu, Mm, Rt                    ab17205
ALS2CR3                                    P        Fast track                          Gt        Fast track                     ab4200   Pep. avail.
Apolipoprotein E                           P        ELISA, IHC-P, WB                    Gt        Hu                             ab7620
Apolipoprotein E                           P        ID, IE, RID, WB                     Rb        Mm                            ab20874
Apolipoprotein E [E6D7]                    M        ELISA, IHC-Fr, IHC-P, IP, WB        Mm        Hu                             ab1907
Calpastatin                                P        ELISA, WB                           Ch        Hu                            ab16423
Calpastatin [2G11D6]                       M        ICC, WB                             Mm        Hu, Rt, C, Pi                  ab3515
Caspase 6                                  P        WB                                  Rb        Hu, Mm, Rt                     ab2552
Caspase 6                                  P        ELISA, WB                           Rb        Hu, Mm, Rt                    ab18520
Caspase 6                                  P        WB                                  Rb        Hu                            ab19920
Caspase 6 [3F51]                           M        IHC-P, IP, WB                       Mm        Hu                            ab17866
Caspase 6 [3F52]                           M        IHC-P, IP, WB                       Mm        Hu                            ab17822
Caspase 6 [6CSP01 (7165)]                  M        IP                                  Mm        Hu                             ab3245
Caspase 6 [6CSP03]                         M        WB                                  Mm        Hu                             ab4062
CCKAR                                      P        WB                                  Rb        Hu                            ab14441
Drebrin                                    P        WB                                  Rb        Rt, Hu                        ab11068
Drebrin [M2F6]                             M        IHC-Fr, IHC-P, WB                   Mm        Hu, Mm, Rt, Ch, F, Gp, Mk     ab12350
ERAB                                       P        ELISA, IF, IHC-P, WB                Rb        Hu                            ab17298
ERAB [5F3]                                 M        Dot, ELISA, IF, IHC-Fr, IHC-P, WB   Mm        Hu                            ab10260
Fyn                                        P        ELISA, WB                           Gt        Hu                              ab802   Pep. avail.


            ApoE antibody [D6E10] (ab1906)

                            IHC-P - ab1906 reactivity with Apo E of vascular amyloid beta in a Down Syndrome tissue section.


                            Clonality    Applications tested                 Host       Species reactivity             Datasheet
                               M         WB, IHC-P, IHC-Fr                   Mm         Hu                             www.abcam.com/ab1906




Customer Service
Tel: Europe +44 (0) 1223 696000 | U.S.A. 1 617 225 2272 (Toll free: 1 888 77 ABCAM)                                                                     19
Neuroscience > Neurodegeneration > Alzheimer’s > Related targets

                         Target                                    Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                                                         www.abcam.com/...

                         Fyn                                          P        WB                                Rb       Hu, Mm                           ab13955
                         Fyn [1S]                                     M        IHC-P                             Mm       Hu, Rt, Mm                        ab3116
                         Fyn [FYN-01]                                 M        ICC, IP, WB                       Mm       Hu, Mm                            ab1881
                         PHF2                                         P        WB                                Rb       Hu                                ab1138
                         Synuclein (alpha)                            P        H, ICC, IHC, IHC-Fr, IHC-P, WB    Sh       Hu                                ab6162
                         Synuclein (alpha)                            P        IHC-P                             Rb       Hu, Rt                           ab15530
                         Synuclein (alpha)                            P        ICC, WB                           Gp       Hu, Mm, Rt, B                    ab16784
                         Synuclein (alpha) (phospho Y125)             P        Fast track                        Rb       Fast track                       ab10789 Pep. avail.
                         Synuclein (alpha) [4B12]                     M        Dot, ELISA, IHC-Fr, IHC-P, WB     Mm       Hu.
                                                                                                                          Does not react with Mm or Rt      ab1904
                         Synuclein   (alpha) [4D6]                    M        ELISA, IHC-Fr, IHC-P, WB          Mm       Hu, Mm, Rt                        ab1903
                         Synuclein   (beta)                           P        ICC, IHC-Fr, IHC-P, WB            Rb       Hu                                ab6165
                         Synuclein   (beta)                           P        IHC-Fr, IHC-P                     Sh       Hu                                ab6163
                         Synuclein   (beta)                           P        WB                                Ch       Hu                               ab16420
                         Synuclein   (beta)                           P        IHC-P                             Rb       Hu, Rt                           ab15532
                         Synuclein   (gamma)                          P        IHC, IHC-Fr, IHC-P, WB            Rb       Hu, Rt                            ab6169
                         Synuclein   (gamma)                          P        IHC-Fr, IHC-P, WB                 Rb       Hu, Rt                            ab6176
                         Synuclein   (gamma)                          P        IHC-P, WB                         Rb       Hu, Rt                           ab15534
                         Ubiquitin                                    P        ELISA, IF, IHC-F, IHC-Fr,
                                                                               IHC-P, IP, WB                     Rb       Hu, Rt, H, Mm, B                  ab7780
                         Ubiquitin                                    P        ELISA, WB                         Rb       Y                                ab14372
                         Ubiquitin                                    P        WB                                Ch       Hu                               ab19310
Neurodegeneration




                         Ubiquitin [10C2-2]                           M        AP, ELISA, IHC-Fr, IHC-P, WB      Mm       All ubiquitinated proteins         ab411
                         Ubiquitin [1B4-UB]                           M        ELISA, FACS, IHC-Fr, IHC-P, WB    Mm       Hu, B                              ab122



                                            Ubiquitin antibody (ab6309)

                                                       IF - P23H mutant cells immunostained with ab6309 (1/500 dilution) showing co-localization of mutant aggregated
                                                       protein with ubiquitin.



                                                       Clonality    Applications tested                Host     Species reactivity               Datasheet
                                                          P         WB, IHC-Fr, IA, IF                  Rb      C, Sc                            www.abcam.com/ab6309




                         Neuroscience > Neurodegeneration > Alzheimer’s > Proteases

                         Target                                    Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                                                         www.abcam.com/...

                         BACE1                                        P        IHC-P                             Gt       Hu                               ab11028
                         BACE1                                        P        WB                                Rb       Hu, Rt, Mm                        ab2077 Pep. avail.
                         BACE2                                        P        WB                                Rb       Hu, Rt, Mm                        ab8025 Pep. avail.
                         BACE peptide                                          BL                                                                           ab5857
                         Cathepsin H [1D10]                           M        IHC-Fr, IHC-P, WB                 Mm       Hu                                ab7432
                         Nicastrin                                    P        WB                                Rb       Hu,   Mm                          ab3444 Pep. avail.
                         Presenilin 1                                 P        ELISA, IHC-Fr, IHC-P, WB          Gt       Hu                                ab7297
                         Presenilin 1, prediluted                     P        IHC-P                             Rb       Hu                               ab15508
                         Presenilin 1 [APS 11]                        M        ELISA, IF, IHC-P, WB              Mm       Hu,   Mm, Rt                     ab15456
                         Presenilin 1 [APS 18]                        M        ELISA, IF, WB                     Mm       Hu,   Mm, Rt                     ab15458
                         Presenilin 2                                 P        ELISA, IHC, WB                    Ch       Hu,   Mm, Rt                     ab18041
                         Presenilin 2                                 P        ELISA, IHC-Fr, IHC-P              Gt       Hu                               ab11148
                         Presenilin 2 [198C67921]                     M        WB                                Mm       Hu                               ab13926
                         Presenilin 2 [APS 26]                        M        ELISA, IF, WB                     Mm       Hu,   Mm, Rt                     ab15549




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                    20                                                                      Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Neurodegeneration > Alzheimer’s > Tangles & Tau

Target                                   Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                               www.abcam.com/...

14-3-3 tau [3B9]                            M        IP, WB                            Mm       Hu, Mm, Rt, B                    ab10439
Casein Kinase 1 delta                       P        ELISA, IHC-P                      Gt       Hu                               ab10877
ERK1                                        P        IHC-P, IP, WB                     Rb       Hu, Rt, Mm                        ab7947 Pep. avail.
ERK1                                        P        ELISA, IP, WB                     Rb       Hu, Rb, Rt, Mm, C, Pi             ab9363
ERK1 (HRP)                                  P        ELISA, IP, WB                     Rb       Hu, B, Mm, Pi, Rb, Rt             ab9364
ERK1 + ERK2 (phospho T185 + T202)           P        WB                                Rb       Hu                                ab4819 Pep. avail.
ERK1 + ERK2 (phospho T185 + T202) (FITC)    P        FACS, IHC-Fr, WB                  Rb       Hu                                ab4820
ERK1 + ERK2 (phospho T202/183 + Y204/185)   P        WB                                Rb       Hu, Mm, Rt                       ab16869
ERK1 + ERK2 (phospho T202 + Y204)           P        IF                                Rb       Hu, Mm, Rt                       ab20490
ERK1 + ERK2                                 P        IP                                Sh       Hu, Rt                           ab16573
ERK1 + ERK2                                 P        WB                                Rb       Hu, Mm, Rt, B                    ab17942
GSK3 (alpha + beta) (phospho Y216 + Y279)   P        Dot, ELISA, WB                    Rb       Hu, Mm, Rt                        ab4797
GSK3 (alpha + beta)                         P        IHC-P, WB                         Rb       Hu, Mm, Rt, Ch, Mk               ab15314
GSK3 (alpha + beta) [1H8]                   M        ELISA, WB                         Mm       Hu, Mm, Rt, Am                   ab17059
Neurofibrillary Tangle                      P        IHC-Fr, IHC-P, WB                 Rb       Hu                                ab2076
Neurofibrillary Tangle                      P        ELISA, IHC-P, WB                  Rb       Hu                               ab11093
PEN2                                        P        IP, WB                            Rb       Hu                               ab16555
Pin1                                        P        WB                                Rb       Hu                               ab12107 Pep. avail.
Prealbumin                                  P        DID, Ie, RID, RIe                 Sh       Hu, B, F, Ch, D, Gt, Gp, H,
                                                                                                Mm, Pi, Rb, Rt                    ab9015
Prealbumin                                  P        IHC, RID                          Rb       Hu, B, F, D, H                   ab16006
Prealbumin                                  P        ELISA                             Gt       Hu                               ab15007




                                                                                                                                                              Neurodegeneration
Tau (phospho S199)                          P        WB                                Rb       Hu                                ab4749   Pep. avail.
Tau (phospho S199 + S202)                   P        WB                                Rb       Hu                                ab4864
Tau (phospho S202)                          P        IHC-Fr, WB                        Rb       Hu                                ab4839   Pep. avail.
Tau (phospho S208)                          P        WB                                Rb       Hu                               ab10892   Pep. avail.
Tau (phospho S214)                          P        WB                                Rb       Hu                                ab4846   Pep. avail.
Tau (phospho S214)                          P        Fast track                        Rb       Fast track                       ab10891   Pep. avail.
Tau (phospho S356)                          P        WB                                Rb       Hu                                ab4857   Pep. avail.
Tau (phospho S262)                          P        WB                                Rb       Hu                                ab4856   Pep. avail.
Tau (phospho S396)                          P        WB                                Rb       Hu                                ab4858   Pep. avail.
Tau (phospho S400)                          P        WB                                Rb       Hu                                ab4859   Pep. avail.
Tau (phospho S404)                          P        WB                                Rb       Hu                                ab4860   Pep. avail.
Tau (phospho S409)                          P        WB                                Rb       Hu                                ab4861   Pep. avail.
Tau (phospho S422)                          P        WB                                Rb       Hu                                ab4862   Pep. avail.
Tau (phospho T181)                          P        WB                                Rb       Hu                                ab4748   Pep. avail.
Tau (phospho T212)                          P        WB                                Rb       Hu                                ab4842   Pep. avail.
Tau (phospho T217)                          P        WB                                Rb       Hu                                ab4851   Pep. avail.
Tau (phospho T231)                          P        WB                                Rb       Hu                                ab4855   Pep. avail.
Tau                                         P        IHC-P, WB                         Gt       Hu                               ab11107
Tau                                         P        IHC-F, WB                         Rb       Hu                               ab22690
Tau                                         P        IF, IHC-Fr, IHC-P                 Rb       Hu                                ab8763
Tau [T1]                                    M        WB                                Mm       Hu, Mm, Rt, B                    ab12354
Tau [Tau]                                   M        IHC-Fr, IHC-P                     Mm       Ch, B, Hu, Mk.
                                                                                                Does not react with Mm or Rt      ab8739
Tau [TAU-5]                                 M        IHC-Fr, IHC-P, WB                 Mm       Hu                                ab3931


                    Tau antibody (ab4841)

                             IF - Transgenic C. elegans first larval stage nematode expressing human wild type Tau GFP (green) and stained with
                             ab4841 (red). Neurons of the head, dorsa and ventral cords and tail region display phosphorylated Tau.




                             Clonality    Applications tested               Host      Species reactivity              Datasheet
                                P         WB, IHC-Fr, IHC (no paRtffin)      Rb       Hu                              www.abcam.com/ab4841
                                          whole animals




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Neuroscience > Neurodegeneration > Alzheimer’s > Tangles & Tau

                         Target                                         Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                                                              www.abcam.com/...

                         Ubiquitin                                         P        IA, IF, IHC-Fr, WB                Rb       C, Sc                            ab6309
                         Ubiquitin                                         P        ELISA, IF, IHC-F, IHC-Fr,
                                                                                    IHC-P, IP, WB                    Rb        Hu, Rt, H, Mm, B                 ab7780
                         Ubiquitin                                         P        ELISA, WB                        Rb        Y                               ab14372
                         Ubiquitin                                         P        WB                               Ch        Hu                              ab19310
                         Ubiquitin [10C2-2]                                M        AP, ELISA, IHC-Fr, IHC-P, WB     Mm        All ubiquitinated proteins        ab411
                         Ubiquitin [1B4-UB]                                M        ELISA, FACS, IHC-Fr, IHC-P, WB   Mm        Hu, B                             ab122



                         Neuroscience > Neurodegeneration > Huntington’s

                         Target                                         Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                                                              www.abcam.com/...

                         HAP40                                             P        IP, WB                           Rb        Mm                               ab1139
                         HAP40                                             P        ELISA, WB                        Rb        Hu                               ab1400
                         HIPPI                                             P        WB                               Rb        Hu                               ab5205
                         Huntingtin [1A771]                                M        WB                               Mm        Many                            ab13583
                         Huntingtin [HDA3E10]                              M        IF, IHC-Fr, IP, WB               Mm        Hu, Rt, Mm                       ab7668
                         Huntingtin Interacting Protein HIP1 [4B10]        M        WB                               Mm        Hu                               ab5402
                         Huntingtin Interacting Protein HIP1
                         [4B107], prediluted                               M        IHC-P                            Mm        Hu.
Neurodegeneration




                                                                                                                               Does not react with Mm          ab11841
                         Huntingtin Interacting Protein 2                  P        ELISA, WB                         Gt       Hu                              ab21728



                         Neuroscience > Neurodegeneration > Parkinson’s > Related targets

                         Target                                         Clonality   Applications tested              Host      Species reactivity             Datasheet
                                                                                                                                                              www.abcam.com/...

                         ALDH1A1                                           P        WB                                Gt       Hu, Mm.
                                                                                                                               Does not react with Rt           ab9883 Pep. avail.
                         APH1a                                             P        WB                                Rb       Rt, Hu, Mm                      ab12104 Pep. avail.
                         APH1a                                             P        IF, IP, WB                        Rb       Hu, Mm                          ab19390
                         CCKAR                                             P        WB                                Rb       Hu                              ab14441
                         DORFIN                                            P        Fast track                        Gt       Fast track                       ab3997 Pep. avail.
                         DORFIN                                            P        Fast track                        Rb       Fast track                      ab10889


                                          ALDH1A1 antibody (ab24343)

                                                            IF - staining of ALDH1A1-containing neurons in adult mouse brain sections using ab24343.


                                                            Clonality    Applications tested               Host      Species reactivity                Datasheet
                                                               P         IHC-Fr, IHC-FrFl                   Rb       Mm                                www.abcam.com/ab24343




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                    22                                                                           Neuroscience resources: www.abcam.com/neuroscience
Neuroscience > Neurodegeneration > Parkinson’s > Related targets

Target                                  Clonality   Applications tested                Host       Species reactivity               Datasheet
                                                                                                                                   www.abcam.com/...

PGP95                                      P        WB                                  Gt        Hu                                ab11145
PGP95                                      P        IHC-Fr                              Gp        Hu,   Mm, Rt                      ab10410
PGP95                                      P        IHC-P                               Rb        Hu                                ab15503
PGP95 [13C4 / I3C4]                        M        IF, IHC-F, IHC-Fr, IHC-P            Mm        Hu,   Rt, Gp                       ab8189
PGP95 [31A3]                               M        ELISA, IHC-P, WB                    Mm        Hu,   Rt                          ab20559
PINK1                                      P        IHC-P, WB                           Rb        Hu,   Mm, Rt                      ab23707
SIAH1                                      P        WB                                  Gt        Hu                                 ab2237 Pep. avail.
Synphilin 1                                P        IHC-Fr, IHC-P, WB                   Rb        Hu,   Mm, Rt                       ab6179
Synphilin 1                                P        ELISA, IHC-P, WB                    Gt        Hu                                ab11106



                    PGP9.5 antibody (ab10404)

                             IF - ab10404 at a dilution of 1/1000, detecting PGP9.5 in cortical neurons in rat brain tissue sections prepared for free
                             floating IHC (4% PFA fixed, 30µm thick coronal sections).

                             Clonality     Applications tested                  Host     Species reactivity                Datasheet
                                P          WB, IHC-Fr, IF                        Rb      Hu, Mm, Rt, Pi                    www.abcam.com/ab10404




                                                                                                                                                               Neurodegeneration
Neuroscience > Neurodegeneration > Parkinson’s > Parkin / PARK

Target                                  Clonality   Applications tested                Host       Species reactivity              Datasheet
                                                                                                                                  www.abcam.com/...

PARK7                                      P        WB                                  Gt        Hu, Mm                             ab4150 Pep. avail.
PARK7 [malphaDJ-1/E219]                    M        ICC, WB                             Mm        Hu, Fi.
                                                                                                  Does not react with Mm            ab11251
Parkin                                     P        IHC-Fr, WB                          Rb        Hu, Rt                             ab5667 Pep. avail.
Parkin                                     P        Dot, ELISA, IHC-Fr, IHC-P, WB       Rb        Hu, Rt                             ab6177
Parkin                                     P        ELISA, IHC-P, WB                    Gt        Hu                                 ab7296


                    Parkin antibody (ab15494)

                            IHC - ab15494 staining Parkin in Alzheimer’s brain (FFPE-sections).


                            Clonality    Applications tested                   Host    Species reactivity                Datasheet
                               P         IHC-P                                  Rb     Hu, Mm, Rt                        www.abcam.com/ab15494




Neuroscience > Neurodegeneration > Parkinson’s > Synuclein

Target                                  Clonality   Applications tested                Host       Species reactivity              Datasheet
                                                                                                                                  www.abcam.com/...

DORFIN                                     P        Fast track                          Rb        Fast track                        ab10889
DORFIN                                     P        Fast track                          Gt        Fast track                         ab3997 Pep. avail.
HMGB1 [4C3]                                M        WB                                  Mm        Hu, Mm, Rt, C, Pi                 ab11354
HMGB1 [HAP465]                             M        ELISA, WB                           Mm        Hu, Mm, Rt, Ch, D                 ab12029
Synphilin 1                                P        ELISA, IHC-P, WB                    Gt        Hu                                ab11106
Synphilin 1                                P        IHC-Fr, IHC-P, WB                   Rb        Hu                                 ab6179
Synuclein (alpha)                          P        ICC, WB                             Gp        Hu, Mm, Rt, B                     ab16784




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Neuroscience > Neurodegeneration > Parkinson’s > Synuclein

                         Target                                      Clonality   Applications tested              Host       Species reactivity              Datasheet
                                                                                                                                                             www.abcam.com/...

                         Synuclein   (alpha)                            P        IHC-P                             Rb        Hu, Rt                           ab15530
                         Synuclein   (alpha)                            P        H, ICC, IHC, IHC-Fr, IHC-P, WB    Sh        Hu                                ab6162
                         Synuclein   (alpha) (phospho Y125)             P        Fast track                        Rb        Fast track                       ab10789 Pep. avail.
                         Synuclein   (alpha) [4B12]                     M        Dot, ELISA, IHC-Fr, IHC-P, WB     Mm        Hu.
                                                                                                                             Does not react with Mm or Rt      ab1904
                         Synuclein   (beta)                             P        IHC-P                             Rb        Hu, Rt                           ab15532
                         Synuclein   (beta)                             P        WB                                Ch        Hu                               ab16420
                         Synuclein   (beta)                             P        IHC-Fr, IHC-P                     Sh        Hu                                ab6163
                         Synuclein   (beta)                             P        ICC, IHC-Fr, IHC-P, WB            Rb        Hu                                ab6165
                         Synuclein   (gamma)                            P        IHC, IHC-Fr, IHC-P, WB            Rb        Hu, Rt                            ab6169
                         Synuclein   (pan)                              P        IHC-P, WB                         Rb        Hu, Rt                           ab15534
                         Synuclein   (pan)                              P        IHC-Fr, IHC-P, WB                 Rb        Hu, Rt                            ab6176
                         VCP [5]                                        M        IHC-Fr, IHC-P, IP, WB             Mm        Hu, Mm, Rt                       ab11433


                                                  HMGB1 (ab11972)

                                                         ICC- labeling of HMGB1 (red) in HeLa cells using ab11972 (1/50). DNA is stained with DAPI (blue).


                                                         Clonality    Applications tested                 Host    Species reactivity              Datasheet
                                                            P         IF, WB                               Rb     Hu                              www.abcam.com/ab11972
Neurodegeneration




                                         alpha Synuclein [4D6] (ab1903)

                                                         IHC-P - ab1903 stains Lewy Bodies in a substantia nigra neuron.


                                                         Clonality    Applications tested                 Host    Species reactivity              Datasheet
                                                            M         ELISA, WB, IHC-P, IHC-Fr            Mm      Hu, Mm, Rt                      www.abcam.com/ab1903




                         Neuroscience > Neurodegeneration > Prions

                         Target                                      Clonality   Applications tested              Host       Species reactivity              Datasheet
                                                                                                                                                             www.abcam.com/...

                         67kDa Laminin Receptor                         P        ICC, IF, IHC-P, IP, WB            Rb        Hu, Mm                             ab711
                         67kDa Laminin Receptor [MLuC5]                 M        FACS, ICC, IF, IHC-P              Mm        Hu, Rt                            ab3099
                         Fyn                                            P        WB                                Rb        Hu, Mm                           ab13955
                         Fyn                                            P        ELISA, WB                         Gt        Hu                                 ab802 Pep. avail.
                         Fyn [1S]                                       M        IHC-P                             Mm        Hu, Rt, Mm                        ab3116
                         Fyn [FYN-01]                                   M        ICC, IP, WB                       Mm        Hu, Mm                            ab1881
                         Prion protease resistant protein 27-30         P        ELISA, IHC-P, WB                  Gt        Hu                                ab7303
                         Prion protein PrP                              P        ELISA, WB                         Mm        Hu, B                            ab22366
                         Prion protein PrP                              P        ELISA, WB                         Rb        Hu, Mm, B                          ab703
                         Prion protein PrP                              P        Dot, ELISA, IHC, WB               Gt        Hu, B, Sh, Ha                     ab6664
                         Prion protein PrP [1E5 / G6]                   M        ELISA, WB                         Mm        Hu, B                             ab2879
                         Prion protein PrP [1E5 / G6]                   M        ELISA, WB                         Mm        Hu, B                             ab3408
                         Prion protein PrP [3B8 / D5]                   M        ELISA, WB                         Mm        C, Sh                             ab2881
                         Prion protein PrP [7D9]                        M        ELISA, IHC, IHC-F, IHC-P, WB      Mm        Mm, B, De, El, Ha, Hu, Rt        ab14219
                         Prion protein PrP [WD3C7]                      M        ELISA, IP, WB                     Mm        B                                ab13643




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                    24                                                                        Neuroscience resources: www.abcam.com/neuroscience
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