Putrescine, Cadaverine, Spermine and Spermidine - Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) - viXra
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Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
1
Putrescine, Cadaverine, Spermine and Spermidine – Enhanced
Precatalyst Preparation Stabilization and Initiation (EPPSI)
Nano Molecules
◊ ☼
Alireza Heidari1 and Ricardo Gobato2
1
Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA.
2
Laboratory of Biophysics and Molecular Modeling Genesis, State Secretariat of Education of Paraná, CEJC,
St. Rocha Pombo, 953, Center, Bela Vista do Paraíso, Paraná, 86130-000, Brazil.
To cite this article:
Alireza Heidari, Ricardo Gobato, Putrescine, Cadaverine, Spermine and Spermidine – Enhanced Precatalyst
Preparation Stabilization and Initiation (EPPSI) Nano Molecules. Parana Journal of Science and Education.
Vol. 4, No. 5, 2018, pp. 1-14.
Received: June 19, 2018; Accepted: June 23, 2018; Published: July 1, 2018.
Abstract
In the current study, we study Putrescine, Cadaverine, Spermine and Spermidine–Enhanced Precatalyst
Preparation Stabilization and Initiation (EPPSI) Nano molecules incorporation into the Nano Polymeric
Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and
drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron
radiations.
Keywords: Putrescine, Cadaverine, Spermine, Spermidine, Enhanced Precatalyst Preparation Stabilization
and Initiation (EPPSI), Nano Molecules.
◊
E-mail: Scholar.Researcher.Scientist@gmail.com; Alireza.Heidari@calsu.us
☼
E-mail: ricardogobato@seed.pr.gov.br; ricardogobato@hotmail.comParana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
2
1. Introduction
In the current study, we study Putrescine,
Cadaverine, Spermine and Spermidine–Enhanced
Precatalyst Preparation Stabilization and Initiation
(EPPSI) Nano molecules incorporation into the
Nano Polymeric Matrix (NPM) by immersion of
the Nano Polymeric Modified Electrode (NPME)
as molecular enzymes and drug targets for human
cancer cells, tissues and tumors treatment under
synchrotron and synchrocyclotron radiations,
Figure (1). Putrescine originates in putrefying and
rotting flesh, and is quite literally, the smell of
death. It is one of the breakdown products of
some of the amino–acids found in animals,
including humans. Although the molecule is a
poisonous solid, as flesh decays the vapor
pressure of the Putrescine it contains becomes
sufficiently large to allow its disgusting odour to Figure 1. Molecular structure of Putrescine,
be detected. It is usually accompanied by Cadaverine, Spermine and Spermidine Nano
Cadaverine (named after the cadavers that give molecules. Source: [28]
rise to it), a poisonous syrupy liquid with an
equally disgusting smell. Putrescine and
Cadaverine also contribute towards the smells of 2. Martials, Research Methods and
some living processes. Since they are both Experimental Techniques
poisonous, the body normally excretes them in Electrochemical polymerization offers the
whatever way is quickest and most convenient.
advantage of reproducible deposition in terms of
For example, the odour of bad breath and urine Nano film thickness and loading, making the
are 'enriched' by the presence of these molecules, immobilization procedure of a metal–based
as is the 'fishy' smell of the discharge from the electrocatalyst very simple and reliable for
female medical condition bacterial vaginosis.
Putrescine, Cadaverine, Spermine and
Putrescine and Cadaverine also contribute to the
Spermidine–Enhanced Precatalyst Preparation
distinctive smell of semen, which also contains Stabilization and Initiation (EPPSI) Nano
the related molecules Spermine and Spermidine. molecules–encapsulating Carbon nanotubes
In this regard, the development of Chemical incorporation into the Nano Polymeric Matrix
Modified Electrodes (CEMs) is at present an area (NPM) by immersion of the Nano Polymeric
of great interest. CEMs can be divided broadly
Modified Electrode (NPME) as molecular
into two main categories; namely, surface enzymes and drug targets for human cancer cells,
modified and bulk modified electrodes. Methods tissues and tumors treatment under synchrotron
of surface modification include adsorption, and synchrocyclotron radiations. Also, it must be
covalent bonding, attachment of polymer Nano notice that the nature of working electrode
films, etc. Polymer Nano film coated electrodes substrate in electropreparation of polymeric Nano
can be differentiated from other modification film is very important, because properties of
methods such as adsorption and covalent bonding polymeric Nano films depend on the working
in that they usually involve multilayer as opposed electrode anti–cancer Nano materials. The ease
to monolayer frequently encountered for the latter and fast preparation and of obtaining a new
methods. The thicker Nano films imply more reproducible surface, the low residual current,
active sites which lead to larger analytical signals. porous surface and low cost of Multi–Walled
This advantage coupled with other, their Carbon Nanotubes (MWCNTs) paste are some
versatility and wide applicability, makes polymer advantages of Carbon Paste Electrode (CPE) over
Nano film modified electrodes particularly all other solid electrodes [29–93].
suitable for analytical applications [1–27].Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
3
3. Results and Discussion
On the other hand, it has been shown that, electropolymerization at the surface of Multi–
macrocyclic complexes of Putrescine, Cadaverine, Walled Carbon Nanotubes (MWCNTs) paste
Spermine and Spermidine–Enhanced Precatalyst electrode. Then, Putrescine, Cadaverine,
Preparation Stabilization and Initiation (EPPSI) Spermine and Spermidine–Enhanced Precatalyst
Nano molecules–encapsulating Carbon nanotubes Preparation Stabilization and Initiation (EPPSI)
are interest as modifying agents because in basic Nano molecules–encapsulating Carbon nanotubes
media Putrescine, Cadaverine, Spermine and were incorporated into the Nano Polymeric
Spermidine–Enhanced Precatalyst Preparation Matrix (NPM) by immersion of the Nano
Stabilization and Initiation (EPPSI) Nano Polymeric Modified Electrode (NPME) in a
molecules–encapsulating Carbon nanotubes redox solution. The modifier layer of Putrescine,
centers show high catalytic activity towards the Cadaverine, Spermine and Spermidine–Enhanced
oxidation of small organic anti–cancer Nano Precatalyst Preparation Stabilization and Initiation
compounds. The high–valence species of (EPPSI) Nano molecules–encapsulating Carbon
Putrescine, Cadaverine, Spermine and nanotubes at the electrode surface acts as a Nano
Spermidine–Enhanced Precatalyst Preparation catalyst for the treatment of human cancer cells,
Stabilization and Initiation (EPPSI) Nano tissues and tumors under synchrotron and
molecules–encapsulating Carbon nanotubes seem synchrocyclotron radiations. Suitability of this
to act as strong oxidizing agents for low– Putrescine, Cadaverine, Spermine and
electroactivity organic substrates. 1,2– Spermidine–Enhanced Precatalyst Preparation
Dioxetane (1,2–Dioxacyclobutane), 1,3– Stabilization and Initiation (EPPSI) Nano
Dioxetane (1,3–Dioxacyclobutane), DMDM molecules–encapsulating Carbon nanotubes–
Hydantoin and Sulphobe as the anti–cancer modified polymeric Multi–Walled Carbon
organic intermediate products of methanol Nanotubes (MWCNTs) paste electrode toward the
oxidation as well as formic acid, is important to electrocatalytic treatment of human cancer cells,
investigate its electrochemical oxidation behavior tissues and tumors under synchrotron and
in Putrescine, Cadaverine, Spermine and synchrocyclotron radiations in alkaline medium at
Spermidine–Enhanced Precatalyst Preparation ambient temperature was investigated.
Stabilization and Initiation (EPPSI) Nano
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DNA/RNA of Human Cancer Cells’ Membranes Technique, Fluid Mech Open Acc 4: 157, 2017.
under Synchrotron Radiations: A Payload–Based
[74] A. Heidari, Concurrent Diagnosis of
Perspective, Arch Chem Res. 1: 2, 2017.
Oncology Influence Outcomes in Emergency
[67] A. Heidari, Deficiencies in Repair of General Surgery for Colorectal Cancer and
Double–Standard DNA/RNA–Binding Molecules Multiple Sclerosis (MS) Treatment Using
Identified in Many Types of Solid and Liquid Magnetic Resonance Imaging (MRI) and
Tumors Oncology in Human Body for Advancing Au329(SR)84, Au329–xAgx(SR)84, Au144(SR)60,
Cancer Immunotherapy Using Computer Au68(SR)36, Au30(SR)18, Au102(SPh)44,Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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Au38(SPh)24, Au38(SC2H4Ph)24, Au21S(SAdm)15, [81] A. Heidari, Elimination of the Heavy Metals
Au36(pMBA)24 and Au25(pMBA)18 Nano Clusters, Toxicity and Diseases in Disruption of
J Surgery Emerg Med 1: 21, 2017. Extracellular Matrix (ECM) Proteins and Cell
Adhesion Intelligent Nanomolecules Adjustment
[75] A. Heidari, Developmental Cell Biology in
in Cancer Metastases Using Metalloenzymes and
Adult Stem Cells Death and Autophagy to Trigger
under Synchrotron Radiation, Lett Health Biol Sci
a Preventive Allergic Reaction to Common
2 (2): 1–4, 2017.
Airborne Allergens under Synchrotron Radiation
Using Nanotechnology for Therapeutic Goals in [82] A. Heidari, Treatment of Breast Cancer Brain
Particular Allergy Shots (Immunotherapy), Cell Metastases through a Targeted Nanomolecule
Biol (Henderson, NV) 6: 1, 2017. Drug Delivery System Based on Dopamine
Functionalized Multi–Wall Carbon
[76] A. Heidari, Changing Metal Powder
Nanotubes (MWCNTs) Coated with Nano
Characteristics for Elimination of the Heavy
Graphene Oxide (GO) and
Metals Toxicity and Diseases in Disruption of
Protonated Polyaniline (PANI) in Situ During the
Extracellular Matrix (ECM) Proteins Adjustment
Polymerization of Aniline Autogenic
in Cancer Metastases Induced by Osteosarcoma,
Nanoparticles for the Delivery of Anti–Cancer
Chondrosarcoma, Carcinoid, Carcinoma, Ewing’s
Nano Drugs under Synchrotron Radiation, Br J
Sarcoma, Fibrosarcoma and Secondary
Res, 4 (3): 16, 2017.
Hematopoietic Solid or Soft Tissue Tumors, J
Powder Metall Min 6: 170, 2017. [83] A. Heidari, Sedative, Analgesic and
Ultrasound–Mediated Gastrointestinal Nano
[77] A. Heidari, Nanomedicine–Based
Drugs Delivery for Gastrointestinal Endoscopic
Combination Anti–Cancer Therapy between
Procedure, Nano Drug–Induced Gastrointestinal
Nucleic Acids and Anti–Cancer Nano Drugs in
Disorders and Nano Drug Treatment of Gastric
Covalent Nano Drugs Delivery Systems for
Acidity, Res Rep Gastroenterol, 1: 1, 2017.
Selective Imaging and Treatment of Human Brain
Tumors Using Hyaluronic Acid, Alguronic Acid [84] A. Heidari, Synthesis, Pharmacokinetics,
and Sodium Hyaluronate as Anti–Cancer Nano Pharmacodynamics, Dosing, Stability, Safety and
Drugs and Nucleic Acids Delivery under Efficacy of Orphan Nano Drugs to Treat High
Synchrotron Radiation, Am J Drug Deliv 5: 2, Cholesterol and Related Conditions and to
2017. Prevent Cardiovascular Disease under
Synchrotron Radiation, J Pharm Sci Emerg Drugs
[78] A. Heidari, Clinical Trials of Dendritic Cell
5: 1, 2017.
Therapies for Cancer Exposing Vulnerabilities in
Human Cancer Cells’ Metabolism and [85] A. Heidari, Non–Linear Compact Proton
Metabolomics: New Discoveries, Unique Features Synchrotrons to Improve Human Cancer Cells
Inform New Therapeutic Opportunities, Biotech's and Tissues Treatments and Diagnostics through
Bumpy Road to the Market and Elucidating the Particle Therapy Accelerators with
Biochemical Programs that Support Cancer Monochromatic Microbeams, J Cell Biol Mol Sci
Initiation and Progression, J Biol Med Science 1: 2 (1): 1–5, 2017.
e103, 2017.
[86] A. Heidari, Design of Targeted Metal
[79] A. Heidari, The Design Graphene–Based Chelation Therapeutics Nanocapsules as Colloidal
Nanosheets as a New Nanomaterial in Anti– Carriers and Blood–Brain Barrier (BBB)
Cancer Therapy and Delivery of Translocation to Targeted Deliver Anti–Cancer
Chemotherapeutics and Biological Nano Drugs Nano Drugs into the Human Brain to Treat
for Liposomal Anti–Cancer Nano Drugs and Gene Alzheimer’s Disease under Synchrotron
Delivery, Br Biomed Bull 5: 305, 2017. Radiation, J Nanotechnol Material Sci 4 (2): 1–5,
2017.
[80] A. Heidari, Integrative Approach to
Biological Networks for Emerging Roles of [87] R. Gobato, A. Heidari, Calculations Using
Proteomics, Genomics and Transcriptomics in Quantum Chemistry for Inorganic Molecule
the Discovery and Validation of Human Simulation BeLi2SeSi, Science Journal of
Colorectal Cancer Biomarkers from DNA/RNA Analytical Chemistry, Vol. 5, No. 6, Pages 76–85,
Sequencing Data under Synchrotron Radiation, 2017.
Transcriptomics 5: e117, 2017.
[88] A. Heidari, Different High–Resolution
Simulations of Medical, Medicinal, Clinical,Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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Pharmaceutical and Therapeutics Oncology of Melphalan, Busulphan and BCNU as Anti–Cancer
Human Lung Cancer Translational Anti–Cancer Drugs, Insights Med Phys. 1: 2, 2016.
Nano Drugs Delivery Treatment Process under
[95] A. Heidari, Potency of Human Interferon β–
Synchrotron and X–Ray Radiations, J Med Oncol.
1a and Human Interferon β–1b in Enzymotherapy,
Vol. 1 No. 1: 1, 2017.
Immunotherapy, Chemotherapy, Radiotherapy,
[89] A. Heidari, A Modern Hormone Therapy and Targeted Therapy of
Ethnomedicinal Technique for Transformation, Encephalomyelitis Disseminate/Multiple Sclerosis
Prevention and Treatment of Human (MS) and Hepatitis A, B, C, D, E, F and G Virus
Malignant Gliomas Tumors into Human Benign Enter and Targets Liver Cells, J Proteomics
Gliomas Tumors under Synchrotron Enzymol 6: 1, 2017.
Radiation, Am J Ethnomed, Vol. 4 No. 1: 10,
[96] A. Heidari, Transport Therapeutic Active
2017.
Targeting of Human Brain Tumors Enable Anti–
[90] A. Heidari, Active Targeted Nanoparticles Cancer Nanodrugs Delivery across the Blood–
for Anti–Cancer Nano Drugs Delivery across the Brain Barrier (BBB) to Treat Brain Diseases
Blood–Brain Barrier for Human Brain Cancer Using Nanoparticles and Nanocarriers under
Treatment, Multiple Sclerosis (MS) and Synchrotron Radiation, J Pharm Pharmaceutics 4
Alzheimer's Diseases Using Chemical (2): 1–5, 2017.
Modifications of Anti–Cancer Nano Drugs or
[97] A. Heidari, Christopher Brown,
Drug–Nanoparticles through Zika Virus (ZIKV)
Combinatorial Therapeutic Approaches to
Nanocarriers under Synchrotron Radiation, J Med
DNA/RNA and Benzylpenicillin (Penicillin G),
Chem Toxicol, 2 (3): 1–5, 2017.
Fluoxetine Hydrochloride (Prozac and Sarafem),
[91] A. Heidari, Investigation of Medical, Propofol (Diprivan), Acetylsalicylic Acid (ASA)
Medicinal, Clinical and Pharmaceutical (Aspirin), Naproxen Sodium (Aleve and
Applications of Estradiol, Mestranol (Norlutin), Naprosyn) and Dextromethamphetamine
Norethindrone (NET), Norethisterone Acetate Nanocapsules with Surface Conjugated
(NETA), Norethisterone Enanthate (NETE) and DNA/RNA to Targeted Nano Drugs for Enhanced
Testosterone Nanoparticles as Biological Imaging, Anti–Cancer Efficacy and Targeted Cancer
Cell Labeling, Anti–Microbial Agents and Anti– Therapy Using Nano Drugs Delivery Systems,
Cancer Nano Drugs in Nanomedicines Based Ann Adv Chem. 1 (2): 061–069, 2017.
Drug Delivery Systems for Anti–Cancer
[98] A. Heidari, High–Resolution Simulations of
Targeting and Treatment, Parana J Sci Educ V.3,
Human Brain Cancer Translational Nano Drugs
n.4, (10–19) October 12, 2017.
Delivery Treatment Process under Synchrotron
[92] A. Heidari, A Comparative Computational Radiation, J Transl Res. 1 (1): 1–3, 2017.
and Experimental Study on Different Vibrational
[99] A. Heidari, Investigation of Anti–Cancer
Biospectroscopy Methods, Techniques and
Nano Drugs’ Effects’ Trend on Human Pancreas
Applications for Human Cancer Cells in Tumor
Cancer Cells and Tissues Prevention, Diagnosis
Tissues Simulation, Modeling, Research,
and Treatment Process under Synchrotron and X–
Diagnosis and Treatment, Open J Anal Bioanal
Ray Radiations with the Passage of Time Using
Chem 1 (1): 014–020, 2017.
Mathematica, Current Trends. Anal Bioanal
[93] A. Heidari, Combination of DNA/RNA Chem, 1 (1): 36–41, 2017.
Ligands and Linear/Non–Linear Visible–
[100] A. Heidari, Pros and Cons Controversy on
Synchrotron Radiation–Driven N–Doped
Molecular Imaging and Dynamics of Double–
Ordered Mesoporous Cadmium Oxide (CdO)
Standard DNA/RNA of Human Preserving Stem
Nanoparticles Photocatalysts Channels Resulted
Cells–Binding Nano Molecules with
in an Interesting Synergistic Effect Enhancing
Androgens/Anabolic Steroids (AAS) or
Catalytic Anti–Cancer Activity, Enz Eng 6: 1,
Testosterone Derivatives through Tracking of
2017.
Helium–4 Nucleus (Alpha Particle) Using
[94] A. Heidari, Combined Theoretical and Synchrotron Radiation, Arch Biotechnol Biomed.
Computational Study of the Belousov– 1 (1): 067–0100, 2017.
Zhabotinsky Chaotic Reaction and Curtius
[101] A. Heidari, Visualizing Metabolic Changes
Rearrangement for Synthesis of Mechlorethamine,
in Probing Human Cancer Cells and Tissues
Cisplatin, Streptozotocin, Cyclophosphamide,
Metabolism Using Vivo 1H or Proton NMR, 13CParana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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NMR, 15N NMR and 31P NMR Spectroscopy and Nanoparticles Sensitivity in Recurrent Ovarian
Self–Organizing Maps under Synchrotron Cancer by Extending the Cadmium Oxide (CdO)
Radiation, SOJ Mater Sci Eng 5 (2): 1–6, 2017. Nanoparticles–Free Interval Using Synchrotron
Radiation Therapy as Antibody–Drug Conjugate
[102] A. Heidari, Cavity Ring–Down
for the Treatment of Limited–Stage Small Cell
Spectroscopy (CRDS), Circular Dichroism
Diverse Epithelial Cancers, Cancer Clin Res Rep,
Spectroscopy, Cold Vapour Atomic Fluorescence
1: 2, e001, 2017.
Spectroscopy and Correlation Spectroscopy
Comparative Study on Malignant and Benign [109] A. Heidari, A Novel and Modern
Human Cancer Cells and Tissues with the Passage Experimental Imaging and Spectroscopy
of Time under Synchrotron Radiation, Enliven: Comparative Study on Malignant and Benign
Challenges Cancer Detect Ther 4 (2): e001, 2017. Human Cancer Cells and Tissues with the Passage
of Time under White Synchrotron Radiation,
[103] A. Heidari, Laser Spectroscopy, Laser–
Cancer Sci Res Open Access 4 (2): 1–8, 2017.
Induced Breakdown Spectroscopy and Laser–
Induced Plasma Spectroscopy Comparative Study [110] A. Heidari, Different High–Resolution
on Malignant and Benign Human Cancer Cells Simulations of Medical, Medicinal, Clinical,
and Tissues with the Passage of Time under Pharmaceutical and Therapeutics Oncology of
Synchrotron Radiation, Int J Hepatol Human Breast Cancer Translational Nano Drugs
Gastroenterol, 3 (4): 079–084, 2017. Delivery Treatment Process under Synchrotron
and X–Ray Radiations, J Oral Cancer Res 1 (1):
[104] A. Heidari, Time–Resolved Spectroscopy
12–17, 2017.
and Time–Stretch Spectroscopy Comparative
Study on Malignant and Benign Human Cancer [111] A. Heidari, Vibrational Decihertz (dHz),
Cells and Tissues with the Passage of Time under Centihertz (cHz), Millihertz (mHz), Microhertz
Synchrotron Radiation, Enliven: (μHz), Nanohertz (nHz), Picohertz (pHz),
Pharmacovigilance and Drug Safety 4 (2): e001, Femtohertz (fHz), Attohertz (aHz), Zeptohertz
2017. (zHz) and Yoctohertz (yHz) Imaging and
Spectroscopy Comparative Study on Malignant
[105] A. Heidari, Overview of the Role of
and Benign Human Cancer Cells and Tissues
Vitamins in Reducing Negative Effect of
under Synchrotron Radiation, International
Decapeptyl (Triptorelin Acetate or Pamoate Salts)
Journal of Biomedicine, 7 (4), 335–340, 2017.
on Prostate Cancer Cells and Tissues in Prostate
Cancer Treatment Process through [112] A. Heidari, Force Spectroscopy and
Transformation of Malignant Prostate Tumors Fluorescence Spectroscopy Comparative Study on
into Benign Prostate Tumors under Synchrotron Malignant and Benign Human Cancer Cells and
Radiation, Open J Anal Bioanal Chem 1 (1): 021– Tissues with the Passage of Time under
026, 2017. Synchrotron Radiation, EC Cancer, 2 (5), 239–
246, 2017.
[106] A. Heidari, Electron Phenomenological
Spectroscopy, Electron Paramagnetic Resonance [113] A. Heidari, Photoacoustic Spectroscopy,
(EPR) Spectroscopy and Electron Spin Resonance Photoemission Spectroscopy and Photothermal
(ESR) Spectroscopy Comparative Study on Spectroscopy Comparative Study on Malignant
Malignant and Benign Human Cancer Cells and and Benign Human Cancer Cells and Tissues with
Tissues with the Passage of Time under the Passage of Time under Synchrotron Radiation,
Synchrotron Radiation, Austin J Anal Pharm BAOJ Cancer Res Ther, 3: 3, 045–052, 2017.
Chem. 4 (3): 1091, 2017.
[114] A. Heidari, J–Spectroscopy, Exchange
[107] A. Heidari, Therapeutic Nanomedicine Spectroscopy (EXSY), Nuclear Overhauser Effect
Different High–Resolution Experimental Images Spectroscopy (NOESY) and Total Correlation
and Computational Simulations for Human Brain Spectroscopy (TOCSY) Comparative Study on
Cancer Cells and Tissues Using Nanocarriers Malignant and Benign Human Cancer Cells and
Deliver DNA/RNA to Brain Tumors under Tissues under Synchrotron Radiation, EMS Eng
Synchrotron Radiation with the Passage of Time Sci J, 1 (2): 006–013, 2017.
Using Mathematica and MATLAB, Madridge J
[115] A. Heidari, Neutron Spin Echo
Nano Tech. Sci. 2 (2): 77–83, 2017.
Spectroscopy and Spin Noise Spectroscopy
[108] A. Heidari, A Consensus and Prospective Comparative Study on Malignant and Benign
Study on Restoring Cadmium Oxide (CdO) Human Cancer Cells and Tissues with the PassageParana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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of Time under Synchrotron Radiation, Int J [123] A. Heidari, Fluorescence Spectroscopy,
Biopharm Sci, 1: 103–107, 2017. Phosphorescence Spectroscopy and Luminescence
Spectroscopy Comparative Study on Malignant
[116] A. Heidari, Vibrational Decahertz (daHz),
and Benign Human Cancer Cells and Tissues
Hectohertz (hHz), Kilohertz (kHz), Megahertz
under Synchrotron Radiation with the Passage of
(MHz), Gigahertz (GHz), Terahertz (THz),
Time, SM J Clin. Med. Imaging, 4 (1): 1018,
Petahertz (PHz), Exahertz (EHz), Zettahertz
2018.
(ZHz) and Yottahertz (YHz) Imaging and
Spectroscopy Comparative Study on Malignant [124] A. Heidari, Nuclear Inelastic Scattering
and Benign Human Cancer Cells and Tissues Spectroscopy (NISS) and Nuclear Inelastic
under Synchrotron Radiation, Madridge J Anal Absorption Spectroscopy (NIAS) Comparative
Sci Instrum, 2 (1): 41–46, 2017. Study on Malignant and Benign Human Cancer
Cells and Tissues under Synchrotron Radiation,
[117] A. Heidari, Two–Dimensional Infrared
Int J Pharm Sci, 2 (1): 1–14, 2018.
Correlation Spectroscopy, Linear Two–
Dimensional Infrared Spectroscopy and Non– [125] A. Heidari, X–Ray Diffraction (XRD),
Linear Two–Dimensional Infrared Spectroscopy Powder X–Ray Diffraction (PXRD) and Energy–
Comparative Study on Malignant and Benign Dispersive X–Ray Diffraction (EDXRD)
Human Cancer Cells and Tissues under Comparative Study on Malignant and Benign
Synchrotron Radiation with the Passage of Time, Human Cancer Cells and Tissues under
J Mater Sci Nanotechnol 6 (1): 101, 2018. Synchrotron Radiation, J Oncol Res; 2 (1): 1–14,
2018.
[118] A. Heidari, Fourier Transform Infrared
(FTIR) Spectroscopy, Near–Infrared [126] A. Heidari, Correlation Two–Dimensional
Spectroscopy (NIRS) and Mid–Infrared Nuclear Magnetic Resonance (NMR) (2D–NMR)
Spectroscopy (MIRS) Comparative Study on (COSY) Imaging and Spectroscopy Comparative
Malignant and Benign Human Cancer Cells and Study on Malignant and Benign Human Cancer
Tissues under Synchrotron Radiation with the Cells and Tissues under Synchrotron Radiation,
Passage of Time, Int J Nanotechnol Nanomed, EMS Can Sci, 1–1–001, 2018.
Volume 3, Issue 1, Pages 1–6, 2018.
[127] A. Heidari, Thermal Spectroscopy,
[119] A. Heidari, Infrared Photo Dissociation Photothermal Spectroscopy, Thermal
Spectroscopy and Infrared Correlation Table Microspectroscopy, Photothermal
Spectroscopy Comparative Study on Malignant Microspectroscopy, Thermal Macrospectroscopy
and Benign Human Cancer Cells and Tissues and Photothermal Macrospectroscopy
under Synchrotron Radiation with the Passage of Comparative Study on Malignant and Benign
Time, Austin Pharmacol Pharm, 3 (1): 1011, Human Cancer Cells and Tissues with the Passage
2018. of Time under Synchrotron Radiation, SM J
Biometrics Biostat, 3 (1): 1024, 2018.
[120] A. Heidari, Novel and Transcendental
Prevention, Diagnosis and Treatment Strategies [128] A. Heidari, A Modern and Comprehensive
for Investigation of Interaction among Human Experimental Biospectroscopic Comparative
Blood Cancer Cells, Tissues, Tumors and Study on Human Common Cancers’ Cells,
Metastases with Synchrotron Radiation under Tissues and Tumors before and after Synchrotron
Anti–Cancer Nano Drugs Delivery Efficacy Using Radiation Therapy, Open Acc J Oncol Med. 1 (1),
MATLAB Modeling and Simulation, Madridge J 2018.
Nov Drug Res, 1 (1): 18–24, 2017.
[129] A. Heidari, Heteronuclear Correlation
[121] A. Heidari, Comparative Study on Experiments such as Heteronuclear Single–
Malignant and Benign Human Cancer Cells and Quantum Correlation Spectroscopy (HSQC),
Tissues with the Passage of Time under Heteronuclear Multiple–Quantum Correlation
Synchrotron Radiation, Open Access J Trans Med Spectroscopy (HMQC) and Heteronuclear
Res, 2 (1): 00026–00032, 2018. Multiple–Bond Correlation Spectroscopy
(HMBC) Comparative Study on Malignant and
[122] M. R. R. Gobato, R. Gobato, A. Heidari,
Benign Human Endocrinology and Thyroid
Planting of Jaboticaba Trees for Landscape Repair
Cancer Cells and Tissues under Synchrotron
of Degraded Area, Landscape Architecture and
Radiation, J Endocrinol Thyroid Res, 3 (1):
Regional Planning, Vol. 3, No. 1, 2018, Pages 1–
555603, 2018.
9, 2018.Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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[130] A. Heidari, Nuclear Resonance Vibrational [137] A. Heidari, Investigation of Bladder Cancer,
Spectroscopy (NRVS), Nuclear Inelastic Breast Cancer, Colorectal Cancer, Endometrial
Scattering Spectroscopy (NISS), Nuclear Inelastic Cancer, Kidney Cancer, Leukemia, Liver, Lung
Absorption Spectroscopy (NIAS) and Nuclear Cancer, Melanoma, Non–Hodgkin Lymphoma,
Resonant Inelastic X–Ray Scattering Pancreatic Cancer, Prostate Cancer, Thyroid
Spectroscopy (NRIXSS) Comparative Study on Cancer and Non–Melanoma Skin Cancer Using
Malignant and Benign Human Cancer Cells and Synchrotron Technology for Proton Beam
Tissues under Synchrotron Radiation, Int J Bioorg Therapy: An Experimental Biospectroscopic
Chem Mol Biol. 6 (1e): 1–5, 2018. Comparative Study, Ther Res Skin Dis 1 (1),
2018.
[131] A. Heidari, A Novel and Modern
Experimental Approach to Vibrational Circular [138] A. Heidari, Attenuated Total Reflectance
Dichroism Spectroscopy and Video Spectroscopy Fourier Transform Infrared (ATR–FTIR)
Comparative Study on Malignant and Benign Spectroscopy, Micro–Attenuated Total
Human Cancer Cells and Tissues with the Passage Reflectance Fourier Transform Infrared (Micro–
of Time under White and Monochromatic ATR–FTIR) Spectroscopy and Macro–Attenuated
Synchrotron Radiation, Glob J Endocrinol Metab. Total Reflectance Fourier Transform Infrared
1 (3). GJEM. 000514–000519, 2018. (Macro–ATR–FTIR) Spectroscopy Comparative
Study on Malignant and Benign Human Cancer
[132] A. Heidari, Pros and Cons Controversy on
Cells and Tissues under Synchrotron Radiation
Heteronuclear Correlation Experiments such as
with the Passage of Time, International Journal
Heteronuclear Single–Quantum Correlation
of Chemistry Papers, 2 (1): 1–12, 2018.
Spectroscopy (HSQC), Heteronuclear Multiple–
Quantum Correlation Spectroscopy (HMQC) and [139] A. Heidari, Mössbauer Spectroscopy,
Heteronuclear Multiple–Bond Correlation Mössbauer Emission Spectroscopy and 57Fe
Spectroscopy (HMBC) Comparative Study on Mössbauer Spectroscopy Comparative Study on
Malignant and Benign Human Cancer Cells and Malignant and Benign Human Cancer Cells and
Tissues under Synchrotron Radiation, EMS Tissues under Synchrotron Radiation, Acta
Pharma J. 1 (1): 002, 2018. Scientific Cancer Biology 2.3: 17–20, 2018.
[133] A. Heidari, A Modern Comparative and [140] A. Heidari, Comparative Study on
Comprehensive Experimental Biospectroscopic Malignant and Benign Human Cancer Cells and
Study on Different Types of Infrared Tissues under Synchrotron Radiation with the
Spectroscopy of Malignant and Benign Human Passage of Time, Organic & Medicinal Chem IJ.
Cancer Cells and Tissues with the Passage of 6 (1): 555676, 2018.
Time under Synchrotron Radiation, J Analyt
[141] A. Heidari, Correlation Spectroscopy,
Molecul Tech. 3 (1): 8, 2018.
Exclusive Correlation Spectroscopy and Total
[134] A. Heidari, Investigation of Cancer Types Correlation Spectroscopy Comparative Study on
Using Synchrotron Technology for Proton Beam Malignant and Benign Human AIDS–Related
Therapy: An Experimental Biospectroscopic Cancers Cells and Tissues with the Passage of
Comparative Study, European Modern Studies Time under Synchrotron Radiation, Int J Bioanal
Journal, Vol. 2, No. 1, 13–29, 2018. Biomed. 2 (1): 001–007, 2018.
[135] A. Heidari, Saturated Spectroscopy and [142] A. Heidari, Biomedical Instrumentation and
Unsaturated Spectroscopy Comparative Study on Applications of Biospectroscopic Methods and
Malignant and Benign Human Cancer Cells and Techniques in Malignant and Benign Human
Tissues with the Passage of Time under Cancer Cells and Tissues Studies under
Synchrotron Radiation, Imaging J Clin Medical Synchrotron Radiation and Anti–Cancer Nano
Sci. 5 (1): 001–007, 2018. Drugs Delivery, Am J Nanotechnol Nanomed. 1
(1): 001–009, 2018.
[136] A. Heidari, Small–Angle Neutron Scattering
(SANS) and Wide–Angle X–Ray Diffraction [143] A. Heidari, Vivo 1H or Proton NMR, 13C
(WAXD) Comparative Study on Malignant and NMR, 15N NMR and 31P NMR Spectroscopy
Benign Human Cancer Cells and Tissues under Comparative Study on Malignant and Benign
Synchrotron Radiation, Int J Bioorg Chem Mol Human Cancer Cells and Tissues under
Biol. 6 (2e): 1–6, 2018. Synchrotron Radiation, Ann Biomet Biostat. 1 (1):
1001, 2018.Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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[144] A. Heidari, Grazing–Incidence Small– [149] A. Heidari, Grazing–Incidence Small–
Angle Neutron Scattering (GISANS) and Angle X–Ray Scattering (GISAXS) and Grazing–
Grazing–Incidence X–Ray Diffraction (GIXD) Incidence Wide–Angle X–Ray Scattering
Comparative Study on Malignant and Benign (GIWAXS) Comparative Study on Malignant and
Human Cancer Cells, Tissues and Tumors under Benign Human Cancer Cells and Tissues under
Synchrotron Radiation, Ann Cardiovasc Surg. 1 Synchrotron Radiation, Insights Pharmacol
(2): 1006, 2018. Pharm Sci 1 (1): 1–8, 2018.
[145] A. Heidari, Adsorption Isotherms and [150] A. Heidari, Acoustic Spectroscopy,
Kinetics of Multi–Walled Carbon Nanotubes Acoustic Resonance Spectroscopy and Auger
(MWCNTs), Boron Nitride Nanotubes (BNNTs), Spectroscopy Comparative Study on Anti–Cancer
Amorphous Boron Nitride Nanotubes (a–BNNTs) Nano Drugs Delivery in Malignant and Benign
and Hexagonal Boron Nitride Nanotubes (h– Human Cancer Cells and Tissues with the Passage
BNNTs) for Eliminating Carcinoma, Sarcoma, of Time under Synchrotron Radiation, Nanosci
Lymphoma, Leukemia, Germ Cell Tumor and Technol 5 (1): 1–9, 2018.
Blastoma Cancer Cells and Tissues, Clin Med Rev
[151] A. Heidari, Niobium, Technetium,
Case Rep 5: 201, 2018.
Ruthenium, Rhodium, Hafnium, Rhenium,
[146] A. Heidari, Correlation Spectroscopy Osmium and Iridium Ions Incorporation into the
(COSY), Exclusive Correlation Spectroscopy Nano Polymeric Matrix (NPM) by Immersion of
(ECOSY), Total Correlation Spectroscopy the Nano Polymeric Modified Electrode (NPME)
(TOCSY), Incredible Natural–Abundance as Molecular Enzymes and Drug Targets for
Double–Quantum Transfer Experiment Human Cancer Cells, Tissues and Tumors
(INADEQUATE), Heteronuclear Single– Treatment under Synchrotron and
Quantum Correlation Spectroscopy (HSQC), Synchrocyclotron Radiations, Nanomed
Heteronuclear Multiple–Bond Correlation Nanotechnol, 3 (2): 000138, 2018.
Spectroscopy (HMBC), Nuclear Overhauser
[152] A. Heidari, Homonuclear Correlation
Effect Spectroscopy (NOESY) and Rotating
Experiments such as Homonuclear Single–
Frame Nuclear Overhauser Effect Spectroscopy
Quantum Correlation Spectroscopy (HSQC),
(ROESY) Comparative Study on Malignant and
Homonuclear Multiple–Quantum Correlation
Benign Human Cancer Cells and Tissues under
Spectroscopy (HMQC) and Homonuclear
Synchrotron Radiation, Acta Scientific
Multiple–Bond Correlation Spectroscopy
Pharmaceutical Sciences 2.5: 30–35, 2018.
(HMBC) Comparative Study on Malignant and
[147] A. Heidari, Small–Angle X–Ray Scattering Benign Human Cancer Cells and Tissues under
(SAXS), Ultra–Small Angle X–Ray Scattering Synchrotron Radiation, Austin J Proteomics
(USAXS), Fluctuation X–Ray Scattering (FXS), Bioinform & Genomics. 5 (1): 1024, 2018.
Wide–Angle X–Ray Scattering (WAXS),
[153] A. Heidari, Atomic Force Microscopy
Grazing–Incidence Small–Angle X–Ray
Based Infrared (AFM–IR) Spectroscopy and
Scattering (GISAXS), Grazing–Incidence Wide–
Nuclear Resonance Vibrational Spectroscopy
Angle X–Ray Scattering (GIWAXS), Small–
Comparative Study on Malignant and Benign
Angle Neutron Scattering (SANS), Grazing–
Human Cancer Cells and Tissues under
Incidence Small–Angle Neutron Scattering
Synchrotron Radiation with the Passage of Time.
(GISANS), X–Ray Diffraction (XRD), Powder
J Appl Biotechnol Bioeng. 5 (3): 142‒148, 2018.
X–Ray Diffraction (PXRD), Wide–Angle X–Ray
Diffraction (WAXD), Grazing–Incidence X–Ray [154] A. Heidari, Time–Dependent Vibrational
Diffraction (GIXD) and Energy–Dispersive X– Spectral Analysis of Malignant and Benign
Ray Diffraction (EDXRD) Comparative Study on Human Cancer Cells and Tissues under
Malignant and Benign Human Cancer Cells and Synchrotron Radiation, J Cancer Oncol, 2 (2):
Tissues under Synchrotron Radiation, Oncol Res 000124, 2018.
Rev, Volume 1 (1): 1–10, 2018.
[155] A. Heidari, Palauamine and Olympiadane
[148] A. Heidari, Pump–Probe Spectroscopy and Nano Molecules Incorporation into the Nano
Transient Grating Spectroscopy Comparative Polymeric Matrix (NPM) by Immersion of the
Study on Malignant and Benign Human Cancer Nano Polymeric Modified Electrode (NPME) as
Cells and Tissues with the Passage of Time under Molecular Enzymes and Drug Targets for Human
Synchrotron Radiation, Adv Material Sci Engg, Cancer Cells, Tissues and Tumors Treatment
Volume 2, Issue 1, Pages 1–7, 2018.Parana Journal of Science and Education (PJSE) – v.4, n.5, (1-14) July 1, 2018
ISSN: 2447-6153 https://sites.google.com/site/pjsciencea
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under Synchrotron and Synchrocyclotron [160] A. Heidari, Tetrakis [3, 5–bis
Radiations, Arc Org Inorg Chem Sci 3(1), 2018. (Trifluoromethyl) Phenyl] Borate (BARF)–
Enhanced Precatalyst Preparation Stabilization
[156] R. Gobato, A. Heidari, Infrared Spectrum
and Initiation (EPPSI) Nano Molecules, Medical
and Sites of Action of Sanguinarine by Molecular
Research and Clinical Case Reports 2.1: 112–
Mechanics and ab initio Methods, International
125, 2018.
Journal of Atmospheric and Oceanic Sciences.
Vol. 2, No. 1, pp. 1–9, 2018. [161] A. Heidari, Heteronuclear Single–Quantum
Correlation Spectroscopy (HSQC) and
[157] A. Heidari, Gamma Linolenic Methyl Ester,
Heteronuclear Multiple–Bond Correlation
5–Heptadeca–5,8,11–Trienyl 1,3,4–Oxadiazole–
Spectroscopy (HMBC) Comparative Study on
2–Thiol, Sulphoquinovosyl Diacyl Glycerol,
Malignant and Benign Human Cancer Cells,
Ruscogenin, Nocturnoside B, Protodioscine B,
Tissues and Tumors under Synchrotron and
Parquisoside–B, Leiocarposide, Narangenin, 7–
Synchrocyclotron Radiations, Chronicle of
Methoxy Hespertin, Lupeol, Rosemariquinone,
Medicine and Surgery 2.3: 151–163, 2018.
Rosmanol and Rosemadiol Nano Molecules
Incorporation into the Nano Polymeric Matrix [162] A. Heidari, Sydnone, Münchnone,
(NPM) by Immersion of the Nano Polymeric Montréalone, Mogone, Montelukast, Quebecol
Modifi ed Electrode (NPME) as Molecular and Palau’amine–Enhanced Precatalyst
Enzymes and Drug Targets for Human Cancer Preparation Stabilization and Initiation (EPPSI)
Cells, Tissues and Tumors Treatment under Nano Molecules, Sur Cas Stud Op Acc J. 1 (3),
Synchrotron and Synchrocyclotron Radiations, Int 2018.
J Pharma Anal Acta. 2 (1): 007–014, 2018.
[163] A. Heidari, Fornacite, Orotic Acid,
[158] A. Heidari, Angelic Acid, Diabolic Acids, Rhamnetin, Sodium Ethyl Xanthate (SEX) and
Draculin and Miraculin Nano Molecules Spermine (Spermidine or Polyamine)
Incorporation into the Nano Polymeric Matrix Nanomolecules Incorporation into the
(NPM) by Immersion of the Nano Polymeric Nanopolymeric Matrix (NPM), International
Modified Electrode (NPME) as Molecular Journal of Biochemistry and Biomolecules, Vol.
Enzymes and Drug Targets for Human Cancer 4: Issue 1: 1–19, 2018.
Cells, Tissues and Tumors Treatment Under
[164] R. Gobato, A. Heidari, Molecular
Synchrotron and Synchrocyclotron Radiations,
Mechanics and Quantum Chemical Study on Sites
Med & Analy Chem Int J, 2 (1): 000111, 2018.
of Action of Sanguinarine Using Vibrational
[159] A. Heidari, Fourier Transform Infrared Spectroscopy Based on Molecular Mechanics and
(FTIR) Spectroscopy, Attenuated Total Quantum Chemical Calculations, Malaysian
Reflectance Fourier Transform Infrared (ATR– Journal of Chemistry, Vol. 20(1), 1–23, 2018.
FTIR) Spectroscopy, Micro–Attenuated Total
[165] A. Heidari, Vibrational Spectroscopic
Reflectance Fourier Transform Infrared (Micro–
Studies on Anti–cancer Nanopharmaceuticals
ATR–FTIR) Spectroscopy, Macro– Attenuated
(Part I), Malaysian Journal of Chemistry, Vol.
Total Reflectance Fourier Transform Infrared
20(1), 33 – 73, 2018.
(Macro–ATR–FTIR) Spectroscopy, Two–
Dimensional Infrared Correlation Spectroscopy, [166] A. Heidari, Vibrational Spectroscopic
Linear Two–Dimensional Infrared Spectroscopy, Studies on Anti–cancer Nanopharmaceuticals
Non–Linear Two–Dimensional Infrared (Part II), Malaysian Journal of Chemistry, Vol.
Spectroscopy, Atomic Force Microscopy Based 20(1), 74 – 117, 2018.
Infrared (AFM–IR) Spectroscopy, Infrared [167] A. Heidari, Modern Approaches in
Photodissociation Spectroscopy, Infrared Designing Ferritin, Ferritin Light Chain,
Correlation Table Spectroscopy, Near–Infrared Transferrin, Beta–2 Transferrin and
Spectroscopy (NIRS), Mid–Infrared Spectroscopy Bacterioferritin–Based Anti–Cancer Nano Drugs
(MIRS), Nuclear Resonance Vibrational Encapsulating Nanosphere as DNA–Binding
Spectroscopy, Thermal Infrared Spectroscopy and Proteins from Starved Cells (DPS), Mod Appro
Photothermal Infrared Spectroscopy Comparative Drug Des. 1 (1). MADD.000504. 2017.
Study on Malignant and Benign Human Cancer
Cells and Tissues under Synchrotron Radiation
with the Passage of Time, Glob Imaging Insights,
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