PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
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7th Matter & Technology Meeting | 02.02.2021
PLASMED X: COMPACT TUNABLE X-RAY SOURCE
Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel,
Lucas Schaper, Theresa Staufer, Jon Wood, Kristjan Põder, Jens Osterho
Research Group for Plasma Wake eld Accelerators
Deutsches Elektronen-Synchrotron DESY, Machine Division, Hamburg, Germany
Accelerator Research and Development, Matter and Technologies
Helmholtz Association of German Research Centres, Berlin, Germany
fi
fA new light source for XFI
Innovation Pool project to unlock the many bene ts of XFI
> X-Ray Fluorescence Imaging (1) provides key advantages
> High X-Ray energy reduces dose
> No false positives
> Excellent spatial resolution
> Ability to functionalise nanoparticles
> X-Ray beam must be low divergence, narrowband, bright
> Microfocus tubes: high divergence and bandwidth
> Synchrotrons: inaccessible scale and cost
> …? 10 0
> Compact and a ordable X-ray source required!
> PLASMED X project
> BMBF InnovationPool, 2019-2020 10 -1
Transmission
> Demonstrate an all-optical X-Ray source for XFI of a mouse
phantom
10 -2
1 cm
5 cm
10 cm
10 -3
10 1 10 2
Photon energy / keV
(1) Grüner et al, Sci Rep 8, 16561 (2018) 2
Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
ff
fiThe PLASMED X light source
A unique combination of novel technologies results in a peerless light source
> Laser driven electron source - ultra-compact
> Plasma based electron optics for beam manipulation X-rays
> Allows for restricted bandwidth and tuning
n et
> Very strong focussing elds - ultra-compact ag
le m
> Thomson scattering for X-ray generation Scattering laser i p o
D
> Undulator with a period of microns - ultra-compact
> X-ray energy predominantly determined by electron
beam
> Radiation with low divergence
LPA laser
Active plasma
lens
2
Plasma 2 (1 cos ↵) 2
source ~! = ~!L ⇠ 4 ~!L
1 + a20 /2 + 2 ✓2
3
Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
fiCompact, narrowband, tunable X-ray source
First demonstration of LPA and APL combination for X-ray generation
> Commissioned a robust laser plasma accelerator electron
source (1)
> Stable operation over 8 h demonstrated
> Developed theoretical concept showing bandwidth
narrowing (2) and tuning (3) with active plasma
a lens (4)
> Constructed proof-of-principle machine with APL enabled Compton
spectrum control interaction
> First demonstration of restricted bandwidth! (5)
> First demonstration of X-ray tuning (5) Plasma lens
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LW la
se in
Gas jet
la ter
FA se
at
dr r
Sc
iv
e
b c d
(1) Bohlen et al, in preparation
(2) Brümmer et al, PRAB 23 (2020)
(3) Brümmer et al, in preparation
(4) van Tilborg et al, PRL 115 (2015)
4
Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
(5) Meisel et al, in preparationSuccessful detection of uorescence signal
PLASMED X source shown to excite uorescence in medically-used nanoparticles
> Proof-of-principle experiments with the PLASMED X
source
> Detection of uorescence from gold nanoparticles
> Detection of uorescence from gadolinium
nanoparticles
> XFI imaging of mouse phantom upcoming
> Foreseen in Q1 2021
> Custom-designed detectors to be tested in Q2 2021
5
Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
fl
fl
fl
flPLASMED X all-optical X-ray source for XFI
Successful demonstration of compact tunable light source for medical imaging
> Proof-of-principle demonstration of an all-optical X-Ray
source for XFI on a mouse phantom
> BMBF InnovationPool 2019-2020
> Aim to continue with 3rd party technology-transfer funding
> Robust laser plasma accelerator electron source commissioned
> Successfully detected uorescence from medically-used
nanoparticles
> First demonstration of bandwidth narrowing and tunability by an
APL
> Custom-designed X-ray detectors from KIT to be tested Q2 2021
> Next step: Imaging of mouse phantom
> Future: high rep rate implementation @ KALDERA
2 2 (1 cos ↵) 2
~! = ~!L ⇠4 ~!L 6
Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
1 + a20 /2 + 2 ✓2
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